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Aliases for MKRN2OS Gene

Aliases for MKRN2OS Gene

  • MKRN2 Opposite Strand 2 3 5
  • MKRN2 Antisense Gene Protein 1 3 4
  • MKRN2 Antisense RNA 1 2 4
  • MKRN2-AS1 3 4
  • C3orf83 3 4
  • MKRN2 Antisense RNA 1 (Non-Protein Coding) 3
  • Chromosome 3 Open Reading Frame 83 2
  • MKRN2 Opposite Strand Protein 3

External Ids for MKRN2OS Gene

Previous HGNC Symbols for MKRN2OS Gene

  • MKRN2-AS1
  • C3orf83

Summaries for MKRN2OS Gene

GeneCards Summary for MKRN2OS Gene

MKRN2OS (MKRN2 Opposite Strand) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MKRN2OS Gene

Genomics for MKRN2OS Gene

Regulatory Elements for MKRN2OS Gene

Enhancers for MKRN2OS Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH03F012661 0.4 ENCODE 17.5 -102.4 -102391 3.5 PKNOX1 ARNT CREB3L1 ARID4B SIN3A DMAP1 YBX1 ZNF2 YY1 SLC30A9 TAMM41 MKRN2OS RAF1 MKRN2 TSEN2 GC03M012623
GH03F012642 1.4 FANTOM5 Ensembl ENCODE 17.4 -85.4 -85442 7.8 HDGF PKNOX1 MLX WRNIP1 ARID4B DMAP1 ZNF48 YY1 SLC30A9 ZNF121 MKRN2 RAF1 MKRN2OS CRIP1P1 TAMM41 TSEN2 GC03M012623
GH03F012653 0.2 Ensembl 17.4 -92.8 -92842 1.4 BCOR KLF1 ZMYM3 CEBPG NFXL1 ZNF664 ADNP ZSCAN29 SMARCA5 SCRT1 MKRN2 MKRN2OS TSEN2 RAF1 GC03M012623
GH03F012657 0.2 ENCODE 17 -98.3 -98323 3.1 HDGF PKNOX1 FEZF1 ZNF2 KLF7 JUNB TSHZ1 ZNF264 MEF2D SMARCA4 MKRN2 TAMM41 VGLL4 MKRN2OS TSEN2 RAF1 GC03M012623
GH03F012575 0.7 ENCODE 11.9 -15.4 -15417 1.3 ZNF121 ZNF341 BHLHE40 FOS MKRN2OS RAF1 TSEN2 ENSG00000274514
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MKRN2OS on UCSC Golden Path with GeneCards custom track

Genomic Location for MKRN2OS Gene

Chromosome:
3
Start:
12,514,934 bp from pter
End:
12,561,059 bp from pter
Size:
46,126 bases
Orientation:
Minus strand

Genomic View for MKRN2OS Gene

Genes around MKRN2OS on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MKRN2OS Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MKRN2OS Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MKRN2OS Gene

Proteins for MKRN2OS Gene

  • Protein details for MKRN2OS Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    H3BPM6-MKROS_HUMAN
    Recommended name:
    MKRN2 opposite strand protein
    Protein Accession:
    H3BPM6

    Protein attributes for MKRN2OS Gene

    Size:
    223 amino acids
    Molecular mass:
    25451 Da
    Quaternary structure:
    No Data Available

neXtProt entry for MKRN2OS Gene

Post-translational modifications for MKRN2OS Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MKRN2OS Gene

No data available for DME Specific Peptides for MKRN2OS Gene

Domains & Families for MKRN2OS Gene

Protein Domains for MKRN2OS Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MKRN2OS: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MKRN2OS Gene

Function for MKRN2OS Gene

Animal Model Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MKRN2OS Gene

Localization for MKRN2OS Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MKRN2OS Gene

Pathways & Interactions for MKRN2OS Gene

SuperPathways for MKRN2OS Gene

No Data Available

Interacting Proteins for MKRN2OS Gene

Gene Ontology (GO) - Biological Process for MKRN2OS Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MKRN2OS Gene

Transcripts for MKRN2OS Gene

mRNA/cDNA for MKRN2OS Gene

(5) REFSEQ mRNAs :
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MKRN2OS Gene

No ASD Table

Relevant External Links for MKRN2OS Gene

GeneLoc Exon Structure for
MKRN2OS
ECgene alternative splicing isoforms for
MKRN2OS

Expression for MKRN2OS Gene

mRNA expression in normal human tissues for MKRN2OS Gene

NURSA nuclear receptor signaling pathways regulating expression of MKRN2OS Gene:

MKRN2OS
genes like me logo Genes that share expression patterns with MKRN2OS: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MKRN2OS Gene

Orthologs for MKRN2OS Gene

This gene was present in the common ancestor of animals.

Orthologs for MKRN2OS Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC100611216 34
  • 99.4 (n)
dog
(Canis familiaris)
Mammalia LOC100688322 34
  • 83.26 (n)
C3orf83 35
  • 80 (a)
OneToOne
cow
(Bos Taurus)
Mammalia LOC782327 34
  • 77.94 (n)
C3orf83 35
  • 75 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC100361147 34
  • 76.85 (n)
mouse
(Mus musculus)
Mammalia 2510049J12Rik 34 35
  • 75.77 (n)
Mkrn2os 16
oppossum
(Monodelphis domestica)
Mammalia C3orf83 35
  • 61 (a)
OneToOne
chicken
(Gallus gallus)
Aves LOC415966 34
  • 59.58 (n)
C3orf83 35
  • 50 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C3orf83 35
  • 58 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii LOC100150803 34
  • 60.25 (n)
C3orf83 (2 of 2) 35
  • 53 (a)
OneToMany
C3orf83 (1 of 2) 35
  • 36 (a)
OneToMany
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP007899 34
  • 46.8 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG9967 34 35
  • 45.1 (n)
worm
(Caenorhabditis elegans)
Secernentea W10D9.3 35
  • 20 (a)
OneToOne
Species where no ortholog for MKRN2OS was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for MKRN2OS Gene

ENSEMBL:
Gene Tree for MKRN2OS (if available)
TreeFam:
Gene Tree for MKRN2OS (if available)

Paralogs for MKRN2OS Gene

No data available for Paralogs for MKRN2OS Gene

Variants for MKRN2OS Gene

Sequence variations from dbSNP and Humsavar for MKRN2OS Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs10539183 -- 12,543,909(+) AAAAA(-/A)TAACA intron-variant, upstream-variant-2KB
rs10588626 -- 12,543,893(+) GTCTC(-/AA)AAAAA intron-variant, upstream-variant-2KB
rs10651248 -- 12,560,478(+) AATGT(-/AAA)AAAAA intron-variant
rs10670373 -- 12,558,537(+) ACACA(-/TT)TTTAT intron-variant
rs111431662 -- 12,552,057(+) GCTCA(C/T)GCCTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for MKRN2OS Gene

Variant ID Type Subtype PubMed ID
dgv763e201 CNV deletion 23290073
dgv850e199 CNV deletion 23128226
esv2751977 CNV gain 17911159
esv3575548 CNV gain 25503493
nsv1000995 CNV gain 25217958
nsv1112379 CNV deletion 24896259
nsv1147269 CNV deletion 26484159
nsv7351 OTHER inversion 18451855

Variation tolerance for MKRN2OS Gene

Gene Damage Index Score: 2.97; 49.49% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for MKRN2OS Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MKRN2OS

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MKRN2OS Gene

Disorders for MKRN2OS Gene

Relevant External Links for MKRN2OS

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MKRN2OS

No disorders were found for MKRN2OS Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MKRN2OS Gene

Publications for MKRN2OS Gene

  1. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny D.M. … Gibbs R.A. (Nature 2006) 3 4 64

Products for MKRN2OS Gene

Sources for MKRN2OS Gene

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