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Aliases for MKRN2OS Gene

Aliases for MKRN2OS Gene

  • MKRN2 Opposite Strand 2 3 5
  • MKRN2 Antisense Gene Protein 1 3 4
  • MKRN2 Antisense RNA 1 2 4
  • MKRN2-AS1 3 4
  • C3orf83 3 4
  • MKRN2 Antisense RNA 1 (Non-Protein Coding) 3
  • Chromosome 3 Open Reading Frame 83 2
  • MKRN2 Opposite Strand Protein 3

External Ids for MKRN2OS Gene

Previous HGNC Symbols for MKRN2OS Gene

  • MKRN2-AS1
  • C3orf83

Summaries for MKRN2OS Gene

GeneCards Summary for MKRN2OS Gene

MKRN2OS (MKRN2 Opposite Strand) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MKRN2OS Gene

Genomics for MKRN2OS Gene

Regulatory Elements for MKRN2OS Gene

Enhancers for MKRN2OS Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH03G012646 1.9 FANTOM5 Ensembl ENCODE dbSUPER 17.4 -87.0 -87042 3.4 HDGF FOXA2 PKNOX1 MLX WRNIP1 ARID4B DMAP1 ZNF48 YY1 SLC30A9 MKRN2 RAF1 MKRN2OS CRIP1P1 TSEN2 GC03M012623
GH03G012655 1.5 Ensembl ENCODE dbSUPER 17.4 -97.3 -97299 5.1 HDGF PKNOX1 FEZF1 ZNF2 KLF7 JUNB TSHZ1 ZNF592 MEF2D SMARCA4 MKRN2 MKRN2OS TSEN2 RAF1 GC03M012623
GH03G012661 1.4 ENCODE dbSUPER 17.5 -102.4 -102391 3.5 CREB3L1 DMAP1 YBX1 YY1 SLC30A9 ZNF143 ZNF263 SP3 NFYC TBX21 TAMM41 MKRN2OS MKRN2 RAF1 TSEN2 GC03M012623
GH03G012719 1.1 Ensembl ENCODE 10.5 -159.2 -159198 1.3 HDAC1 ELF3 PKNOX1 ATF1 FOXA2 RB1 ARID4B SIN3A BMI1 ZNF2 MKRN2OS ENSG00000272263 CAND2 CRIP1P1 TMEM40
GH03G012680 1.6 FANTOM5 Ensembl ENCODE dbSUPER 6.9 -120.9 -120859 2.2 ZNF384 ZIC2 YY1 NFYB NFE2 MAFK NFYA HLF CEBPB SP2 RAF1 MKRN2OS CAND2 CRIP1P1 TMEM40
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MKRN2OS on UCSC Golden Path with GeneCards custom track

Genomic Location for MKRN2OS Gene

12,514,934 bp from pter
12,561,059 bp from pter
46,126 bases
Minus strand

Genomic View for MKRN2OS Gene

Genes around MKRN2OS on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MKRN2OS Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MKRN2OS Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MKRN2OS Gene

Proteins for MKRN2OS Gene

  • Protein details for MKRN2OS Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    MKRN2 opposite strand protein
    Protein Accession:

    Protein attributes for MKRN2OS Gene

    223 amino acids
    Molecular mass:
    25451 Da
    Quaternary structure:
    No Data Available

neXtProt entry for MKRN2OS Gene

Post-translational modifications for MKRN2OS Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MKRN2OS Gene

No data available for DME Specific Peptides for MKRN2OS Gene

Domains & Families for MKRN2OS Gene

Protein Domains for MKRN2OS Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MKRN2OS: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MKRN2OS Gene

Function for MKRN2OS Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MKRN2OS Gene

Localization for MKRN2OS Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MKRN2OS Gene

Pathways & Interactions for MKRN2OS Gene

SuperPathways for MKRN2OS Gene

No Data Available

Interacting Proteins for MKRN2OS Gene

Gene Ontology (GO) - Biological Process for MKRN2OS Gene


No data available for Pathways by source and SIGNOR curated interactions for MKRN2OS Gene

Drugs & Compounds for MKRN2OS Gene

No Compound Related Data Available

Transcripts for MKRN2OS Gene

mRNA/cDNA for MKRN2OS Gene

(5) REFSEQ mRNAs :
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MKRN2OS Gene

No ASD Table

Relevant External Links for MKRN2OS Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MKRN2OS Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MKRN2OS Gene

NURSA nuclear receptor signaling pathways regulating expression of MKRN2OS Gene:

genes like me logo Genes that share expression patterns with MKRN2OS: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MKRN2OS Gene

Orthologs for MKRN2OS Gene

This gene was present in the common ancestor of animals.

Orthologs for MKRN2OS Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC100611216 34
  • 99.4 (n)
(Canis familiaris)
Mammalia LOC100688322 34
  • 83.26 (n)
C3orf83 35
  • 80 (a)
(Bos Taurus)
Mammalia LOC782327 34
  • 77.94 (n)
C3orf83 35
  • 75 (a)
(Rattus norvegicus)
Mammalia LOC100361147 34
  • 76.85 (n)
(Mus musculus)
Mammalia 2510049J12Rik 35 34
  • 75.77 (n)
Mkrn2os 16
(Monodelphis domestica)
Mammalia C3orf83 35
  • 61 (a)
(Gallus gallus)
Aves LOC415966 34
  • 59.58 (n)
C3orf83 35
  • 50 (a)
(Anolis carolinensis)
Reptilia C3orf83 35
  • 58 (a)
(Danio rerio)
Actinopterygii LOC100150803 34
  • 60.25 (n)
C3orf83 (2 of 2) 35
  • 53 (a)
C3orf83 (1 of 2) 35
  • 36 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP007899 34
  • 46.8 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG9967 34 35
  • 45.1 (n)
(Caenorhabditis elegans)
Secernentea W10D9.3 35
  • 20 (a)
Species where no ortholog for MKRN2OS was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for MKRN2OS Gene

Gene Tree for MKRN2OS (if available)
Gene Tree for MKRN2OS (if available)

Paralogs for MKRN2OS Gene

No data available for Paralogs for MKRN2OS Gene

Variants for MKRN2OS Gene

Sequence variations from dbSNP and Humsavar for MKRN2OS Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs1000022363 -- 12,548,821(+) ACAAG(A/C/T)ATCTT intron-variant
rs1000090405 -- 12,549,036(+) TTGAA(C/G)CGATC intron-variant
rs1000129221 -- 12,556,747(+) AGGAG(A/T)GGCTG intron-variant, upstream-variant-2KB
rs1000143842 -- 12,557,990(+) GCTTA(C/G)TGGTA intron-variant
rs1000368371 -- 12,561,181(+) CTTAC(A/G)GAAGT intron-variant, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for MKRN2OS Gene

Variant ID Type Subtype PubMed ID
dgv763e201 CNV deletion 23290073
dgv850e199 CNV deletion 23128226
esv2751977 CNV gain 17911159
esv3575548 CNV gain 25503493
nsv1000995 CNV gain 25217958
nsv1112379 CNV deletion 24896259
nsv1147269 CNV deletion 26484159
nsv7351 OTHER inversion 18451855

Variation tolerance for MKRN2OS Gene

Gene Damage Index Score: 2.97; 49.49% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for MKRN2OS Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MKRN2OS Gene

Disorders for MKRN2OS Gene

Relevant External Links for MKRN2OS

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MKRN2OS Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MKRN2OS Gene

Publications for MKRN2OS Gene

  1. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny D.M. … Gibbs R.A. (Nature 2006) 3 4 64

Products for MKRN2OS Gene

Sources for MKRN2OS Gene

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