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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MKRN2 Gene

protein-coding   GIFtS: 55
GCID: GC03P012598

Makorin Ring Finger Protein 2

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Makorin Ring Finger Protein 21 2
RNF622 3
RING Finger Protein 622 3
Makorin RING Zinc-Finger Protein 22
Probable E3 Ubiquitin-Protein Ligase Makorin-22
EC 6.3.2.-3

External Ids:    HGNC: 71131   Entrez Gene: 236092   Ensembl: ENSG000000759757   OMIM: 6084265   UniProtKB: Q9H0003   

Export aliases for MKRN2 gene to outside databases

Previous GC identifers: GC03P012527 GC03P012573 GC03P012533


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for MKRN2 Gene:
This gene encodes a probable E3 ubiquitin ligase containing several zinc finger domains, that is a member of the
makorin RING zinc-finger protein family. This gene overlaps the v-raf-1 murine leukemia viral oncogene homolog 1
(RAF1) gene in an antisense orientation and may have a co-regulatory function with RAF1. Alternative splicing
results in multiple transcript variants. (provided by RefSeq, Nov 2012)

GeneCards Summary for MKRN2 Gene: 
MKRN2 (makorin ring finger protein 2) is a protein-coding gene. Diseases associated with MKRN2 include leukemia, and chronic lymphocytic leukemia. GO annotations related to this gene include molecular_function and ligase activity. An important paralog of this gene is MKRN3.

UniProtKB/Swiss-Prot: MKRN2_HUMAN, Q9H000
Function: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins (By
similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NC_018914.2  NT_022517.18  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MKRN2 gene promoter:
         FOXF2   Nkx2-2   Bach2   POU3F2   FOXC1   IRF-7A   FOXO1a   NF-kappaB1   Pax-4a   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMKRN2 promoter sequence
   Search SABiosciences Chromatin IP Primers for MKRN2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MKRN2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p25   Ensembl cytogenetic band:  3p25.2   HGNC cytogenetic band: 3p25

MKRN2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MKRN2 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P012598:  view genomic region     (about GC identifiers)

Start:
12,598,513 bp from pter      End:
12,625,212 bp from pter
Size:
26,700 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: MKRN2_HUMAN, Q9H000 (See protein sequence)
Recommended Name: Probable E3 ubiquitin-protein ligase makorin-2  
Size: 416 amino acids; 46940 Da
Miscellaneous: Partially overlaps and is antisense to the RAF1 proto-oncogene
Secondary accessions: A6NIA2 B3KRC5 Q8N391 Q96BD4 Q9BUY2 Q9NRY1

Explore the universe of human proteins at neXtProt for MKRN2: NX_Q9H000

Explore proteomics data for MKRN2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9H000

  • MKRN2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    MKRN2 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001258636.1  NP_054879.3  

    ENSEMBL proteins: 
     ENSP00000170447   ENSP00000396340   ENSP00000397983  

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    Cloud-Clone Corp. Proteins for MKRN2 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular IDA11597136

    MKRN2 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    RNF: RING-type (C3HC4) zinc fingers

    5/6 InterPro protein domains (see all 6):
     IPR000571 Znf_CCCH
     IPR001841 Znf_RING
     IPR026293 Makorin_2
     IPR013083 Znf_RING/FYVE/PHD
     IPR017907 Znf_RING_CS

    Graphical View of Domain Structure for InterPro Entry Q9H000

    ProtoNet protein and cluster: Q9H000

    2 Blocks protein domains:
    IPB000571 Zn-finger
    IPB001841 Zn-finger


    UniProtKB/Swiss-Prot: MKRN2_HUMAN, Q9H000
    Similarity: Contains 4 C3H1-type zinc fingers
    Similarity: Contains 1 RING-type zinc finger


    MKRN2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MKRN2_HUMAN, Q9H000
    Function: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins (By
    similarity)

         Enzyme Number (IUBMB): EC 6.3.2.-1

         Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0003676nucleic acid binding ----
    GO:0005515protein binding ----
    GO:0008270zinc ion binding IEA--
    GO:0016874ligase activity IEA--
         
    MKRN2 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for MKRN2:
     Decreased p24 protein expressi 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for MKRN2 
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    8/25 QIAGEN miScript miRNA Assays for microRNAs that regulate MKRN2 (see all 25):
    hsa-miR-548j hsa-miR-3200-5p hsa-miR-137 hsa-miR-548i hsa-miR-4275 hsa-miR-9 hsa-miR-629 hsa-miR-548a-5p
    SwitchGear 3'UTR luciferase reporter plasmidMKRN2 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    UniProtKB/Swiss-Prot: MKRN2_HUMAN, Q9H000
    Pathway: Protein modification; protein ubiquitination

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MKRN2

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    4 Interacting proteins for MKRN2 (Q9H0003 ENSP000001704474) via UniProtKB, MINT, STRING, and/or I2D

    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBE2KP610863, ENSP000002614274I2D: score=1 STRING: ENSP00000261427
    RBCK1ENSP000003486324STRING: ENSP00000348632
    UBCENSP000003448184STRING: ENSP00000344818
    --B3KSH43I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--
    GO:0016567protein ubiquitination IEA--

    MKRN2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MKRN2

    Search CenterWatch for drugs/clinical trials and news about MKRN2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    About This Section

    REFSEQ mRNAs for MKRN2 gene (2 alternative transcripts): 
    NM_001271707.1  NM_014160.4  

    Unigene Cluster for MKRN2:

    Makorin ring finger protein 2
    Hs.591666  [show with all ESTs]
    Unigene Representative Sequence: NM_014160
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000170447(uc003bxd.3 uc011aus.2) ENST00000411987 ENST00000448482

    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    8/25 QIAGEN miScript miRNA Assays for microRNAs that regulate MKRN2 (see all 25):
    hsa-miR-548j hsa-miR-3200-5p hsa-miR-137 hsa-miR-548i hsa-miR-4275 hsa-miR-9 hsa-miR-629 hsa-miR-548a-5p
    SwitchGear 3'UTR luciferase reporter plasmidMKRN2 3' UTR sequence
    Inhib. RNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MKRN2
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    Additional mRNA sequence: 

    AF302084.1 AK091318.1 AK298463.1 AL834512.1 BC001799.2 BC015715.1 

    12 DOTS entries:

    DT.92451812  DT.100669838  DT.100669840  DT.95208619  DT.92451816  DT.100669851  DT.100669848  DT.120918125 
    DT.120918142  DT.120918155  DT.87008986  DT.97769875 

    24/275 AceView cDNA sequences (see all 275):

    BE502908 CN478542 AA523200 BM786407 AA383521 AL515366 BQ016628 AI566057 
    BF434256 AL834512 R26687 AW005598 AA605183 CA417184 AL523490 AW043645 
    BG248241 BI962835 BE644801 AI218625 AA047830 BG824733 CR610136 BM804239 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for MKRN2    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8 ^ 9
    SP1:                    -                                                               
    SP2:                                                                                    
    SP3:                    -                 -     -     -                                 
    SP4:                    -     -                                                         


    ECgene alternative splicing isoforms for MKRN2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MKRN2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCACCCAAGG
    MKRN2 Expression
    About this image


    See MKRN2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MKRN2

    SOURCE GeneReport for Unigene cluster: Hs.591666

    UniProtKB/Swiss-Prot: MKRN2_HUMAN, Q9H000
    Tissue specificity: Widely expressed

        SABiosciences Expression via Pathway-Focused PCR Array including MKRN2: 
              Ubiquitin Ligases in human mouse rat

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for MKRN2 gene from 9/18 species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mkrn21 , 5 makorin, ring finger protein, 21, 5 85.18(n)1
    88.46(a)1
      6 (53.61 cM)5
    670271  NM_023290.21  NP_075779.21 
     1156019385 
    chicken
    (Gallus gallus)
    Aves MKRN21 makorin ring finger protein 2 73.33(n)
    75.12(a)
      374162  NM_204288.1  NP_989619.1 
    lizard
    (Anolis carolinensis)
    Reptilia MKRN26
    Uncharacterized protein
    72(a)
    1 ↔ 1
    2(158935445-158957033)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.161552 Xenopus laevis transcribed sequence with moderate similarity more 75(n)    BJ081466.1 
    zebrafish
    (Danio rerio)
    Actinopterygii mkrn22 makorin, ring finger protein, 2 74.41(n)   170783  AF277172.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG124773   -- 45(a)
    (best of 4)
      75D7   --
    worm
    (Caenorhabditis elegans)
    Secernentea Y55F3AM.66
    Protein Y55F3AM.6, isoform a
    30(a)
    1 → many
    IV(992289-997652)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT3G085051 E3 ubiquitin-protein ligase makorin 49.14(n)
    40.97(a)
      819998  NM_180209.1  NP_850540.1 
    rice
    (Oryza sativa)
    Liliopsida Os06g03187001 hypothetical protein 48.67(n)
    39.43(a)
      4340884  NM_001064040.1  NP_001057505.1 


    ENSEMBL Gene Tree for MKRN2 (if available)
    TreeFam Gene Tree for MKRN2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MKRN2 gene
    MKRN32  MKRN12  
    3 SIMAP similar genes for MKRN2 using alignment to 3 protein entries:     MKRN2_HUMAN (see all proteins):
    MKRN1    MKRN4P    MKRN3

    MKRN2 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for MKRN2
    PGOHUM00000243604


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/703 SNPs in MKRN2 are shown (see all 703)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1835689711,2
    --12596549(+) CTCGCC/TCGTAA 2 -- us2k10--------
    rs25968221,2
    C,F,O,A,H--12596844(-) TGCTCG/ATAAAA 2 -- us2k1 tfbs331Minor allele frequency- A:0.49NA NS EA WA CSA 2729
    rs353321441,2
    C,F--12596999(+) AAGACT/CCAATA 2 -- us2k15Minor allele frequency- C:0.12NA CSA WA 243
    rs1878134211,2
    --12597048(+) ATACAA/TAACAT 2 -- us2k10--------
    rs1385425131,2
    C--12597148(+) TTAAAC/GTAATT 2 -- us2k10--------
    rs1438044161,2
    --12597199(+) GTATTG/TCCTGG 2 -- us2k10--------
    rs1915680061,2
    --12597202(+) TTGCCA/TGGGAA 2 -- us2k10--------
    rs1845386041,2
    --12597212(+) AGGACA/CATAAG 2 -- us2k10--------
    rs343982371,2
    C,F,H--12597248(+) ATCCAG/ACCCCC 2 -- us2k117Minor allele frequency- A:0.13NS EA NA CSA WA 2217
    rs1874391761,2
    --12597250(+) CCAGCC/TCCCAC 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for MKRN2 (12598513 - 12625212 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for MKRN2:    About this table     
    Variant IDTypeSubtypePubMed ID
    dgv850e199CNV Deletion23128226
    dgv810e201CNV Deletion23290073
    nsv512796CNV Insertion21212237
    nsv876541CNV Gain21882294
    esv2751977CNV Gain17911159
    dgv597n27CNV Gain19166990
    nsv7351OTHER Inversion18451855

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 608426    OMIM disorders: --

    2 diseases for MKRN2:    About MalaCards
    leukemia    chronic lymphocytic leukemia


    MKRN2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): MKRN2
    Human Genome Epidemiology (HuGE) Navigator: MKRN2 (2 documents)

    Export disorders for MKRN2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MKRN2 gene, integrated from 9 sources (see all 19):
    (articles sorted by number of sources associating them with MKRN2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Phylogenetic conservation of the makorin-2 gene, encoding a multiple zinc-finger protein, antisense to the raf1 proto-oncogene. (PubMed id 11597136)1, 2, 3, 9 Gray T.A.... Nicholls R.D. (2001)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2 Zhang Q.-H.... Chen Z. (2000)
    5. Systematic analysis of dimeric E3-RING interactions re veals increased combinatorial complexity in human ubiquitination networks. (PubMed id 22493164)1 Woodsmith J....Sanderson C.M. (2012)
    6. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)
    7. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    8. Activity-based chemical proteomics accelerates inhibi tor development for deubiquitylating enzymes. (PubMed id 22118674)1 Altun M....Kessler B.M. (2011)
    9. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    10. Single nucleotide polymorphisms of matrix metalloprot einase 9 (MMP-9) and tumour protein 73 (TP73) interact with Epstein Barr virus in chronic lymphocytic leukemia: results from the European case-control study E piLymph. (PubMed id 21048031)1 Casabonne D....de Sanjose S. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 23609 HGNC: 7113 AceView: MKRN2 Ensembl:ENSG00000075975 euGenes: HUgn23609
    ECgene: MKRN2 H-InvDB: MKRN2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MKRN2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for MKRN2 gene:
    Search GeneIP for patents involving MKRN2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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