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MIS18BP1 Gene

protein-coding   GIFtS: 45
GCID: GC14M045673

MIS18 Binding Protein 1

(Previous name: chromosome 14 open reading frame 106)
(Previous symbol: C14orf106)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
MIS18 Binding Protein 11 2     HSA2429772
C14orf1061 2 3     hsKNL-22
Kinetochore-Associated Protein KNL-2 Homolog2 3     Kinetochore Null 2 Homolog2
KNL22 3     Mis18-Binding Protein 12
M18BP12 3     Putative Protein P243 Which Interacts With Transcription Factor Sp12
P2432 3     HsKNL-23
Chromosome 14 Open Reading Frame 1061     KIAA19033
Kinetochore Null 2 Homolog (C. Elegans)1     

External Ids:    HGNC: 201901   Entrez Gene: 553202   Ensembl: ENSG000001295347   UniProtKB: Q6P0N03   

Export aliases for MIS18BP1 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for MIS18BP1 Gene:
MIS18BP1 (MIS18 binding protein 1) is a protein-coding gene. GO annotations related to this gene include chromatin binding.

UniProtKB/Swiss-Prot: M18BP_HUMAN, Q6P0N0
Function: Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis

Gene Wiki entry for MIS18BP1 (C14orf106) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Search for regulatory transcription factor binding sites for MIS18BP1
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMIS18BP1 promoter sequence
   Search Chromatin IP Primers for MIS18BP1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MIS18BP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q21.2   Ensembl cytogenetic band:  14q21.2   HGNC cytogenetic band: 14q21.1

MIS18BP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MIS18BP1 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14M045673:  view genomic region     (about GC identifiers)

Start:
45,672,393 bp from pter      End:
45,722,743 bp from pter
Size:
50,351 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: M18BP_HUMAN, Q6P0N0 (See protein sequence)
Recommended Name: Mis18-binding protein 1  
Size: 1132 amino acids; 129085 Da
Subunit: Interacts (via N-terminus) with FLNA (via N-terminus) (By similarity). Interacts with SP1 (Probable).
Interacts with MIS18A. Identified in a complex containing MIS18A, MIS18B, MIS18BP1, RBBP7 and RBBP4
Sequence caution: Sequence=AK002048; Type=Frameshift; Positions=157; Sequence=BAB67796.1; Type=Frameshift;
Positions=154;
1 PDB 3D structure from and Proteopedia for MIS18BP1:
1WGX (3D)    
Secondary accessions: D3DSA7 Q86V14 Q96PY4 Q9NUR5 Q9Y4X9
Alternative splicing: 2 isoforms:  Q6P0N0-1   Q6P0N0-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for MIS18BP1: NX_Q6P0N0

Explore proteomics data for MIS18BP1 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys65, Lys113, Lys458, Lys647, Lys850, Lys1066, Lys1093
  • Modification sites at PhosphoSitePlus

  • See MIS18BP1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_060823.3  
    ENSEMBL proteins: 
     ENSP00000309790   ENSP00000451783   ENSP00000398902   ENSP00000402011   ENSP00000397184  
    Reactome Protein details: Q6P0N0

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    4 InterPro protein domains:
     IPR017884 SANT_dom
     IPR001005 SANT/Myb
     IPR015216 SANTA
     IPR009057 Homeodomain-like

    Graphical View of Domain Structure for InterPro Entry Q6P0N0

    ProtoNet protein and cluster: Q6P0N0

    UniProtKB/Swiss-Prot: M18BP_HUMAN, Q6P0N0
    Similarity: Contains 1 SANT domain


    Find genes that share domains with MIS18BP1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: M18BP_HUMAN, Q6P0N0
    Function: Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0003682chromatin binding IEA--
    GO:0005515protein binding ----
         
    Find genes that share ontologies with MIS18BP1           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MIS18BP1
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    miRTarBase miRNAs that target MIS18BP1:
    hsa-mir-22-3p (MIRT030640), hsa-mir-192-5p (MIRT026637), hsa-mir-421 (MIRT016110), hsa-mir-103a-3p (MIRT027045), hsa-mir-215-5p (MIRT024369)

    Block miRNA regulation of human, mouse, rat MIS18BP1 using miScript Target Protectors
    6 qRT-PCR Assays for microRNAs that regulate MIS18BP1:
    hsa-miR-30c hsa-miR-30a hsa-miR-2117 hsa-miR-30b hsa-miR-30d hsa-miR-30e
    SwitchGear 3'UTR luciferase reporter plasmidMIS18BP1 3' UTR sequence
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    M18BP_HUMAN, Q6P0N0: Nucleus. Chromosome. Chromosome, centromere. Note=Associated with centromeres in interphase
    cells, from late anaphase to the G1 phase. Not detected on centromeres during earlier phases of mitosis.
    Associated with chromatin

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000775chromosome, centromeric region IEA--
    GO:0005654nucleoplasm TAS--

    Find genes that share ontologies with MIS18BP1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for MIS18BP1 About    
    See pathways by source

    SuperPathContained pathways About
    1Packaging Of Telomere Ends
    Chromosome Maintenance0.62
    Deposition of New CENPA-containing Nucleosomes at the Centromere0.59
    Nucleosome assembly0.59
    2Cell Cycle, Mitotic
    Cell Cycle0.90


    Find genes that share SuperPaths with MIS18BP1           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for MIS18BP1
        Deposition of new CENPA-containing nucleosomes at the centromere


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MIS18BP1
    Interactions:

        Search GeneGlobe Interaction Network for MIS18BP1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for MIS18BP1 (Q6P0N03 ENSP000003097904) via UniProtKB, MINT, STRING, and/or I2D (see all 25)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SP1P080473, ENSP000003293574I2D: score=1 STRING: ENSP00000329357
    PCBD1P614573, ENSP000002992994I2D: score=1 STRING: ENSP00000299299
    CASC5ENSP000003354634STRING: ENSP00000335463
    CENPAENSP000003368684STRING: ENSP00000336868
    CENPHENSP000002830064STRING: ENSP00000283006
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006334nucleosome assembly TAS--
    GO:0007067mitosis IEA--
    GO:0034080CENP-A containing nucleosome assembly at centromere TAS--

    Find genes that share ontologies with MIS18BP1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MIS18BP1 (M18BP)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for MIS18BP1 gene: 
    NM_018353.4  

    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000310806(uc001wwf.3 uc010anh.2) ENST00000470424 ENST00000496413
    ENST00000469020 ENST00000554093 ENST00000454990 ENST00000555653 ENST00000453142
    ENST00000494512 ENST00000492652 ENST00000451174
    miRNA
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    6 qRT-PCR Assays for microRNAs that regulate MIS18BP1:
    hsa-miR-30c hsa-miR-30a hsa-miR-2117 hsa-miR-30b hsa-miR-30d hsa-miR-30e
    SwitchGear 3'UTR luciferase reporter plasmidMIS18BP1 3' UTR sequence
    Inhib. RNA
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      QuantiTect SYBR Green Assays in human, mouse, rat MIS18BP1
      QuantiFast Probe-based Assays in human, mouse, rat MIS18BP1

    Selected AceView cDNA sequences (see all 128):

    AA732375 AA250749 AA992666 AA687275 AU137930 BE018278 BX505810 BM834225 
    BQ007537 AI868235 BU618414 BM755242 AB067490 BX110655 CB115229 AV715799 
    AA504111 BF794658 AA371063 AA284210 BF062175 BG940341 AA743026 BG941128 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for MIS18BP1 (see all 8)    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16a · 16b ^ 17a · 17b ^ 18a · 18b ^
    SP1:        -                                   -                                                                                                               
    SP2:                                                                                                                                -     -                 -   
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 19
    SP1:      
    SP2:      
    SP3:      
    SP4:      
    SP5:      


    ECgene alternative splicing isoforms for MIS18BP1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    MIS18BP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    MIS18BP1 Expression
    About this image


    MIS18BP1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 6) fully expand
     
     Ovary (Reproductive System)    fully expand to see all 2 entries
             Ovarian Mesenchymal Stroma Cells Ovary Interstitium
     
     Epithelial Cells
             Presumptive Podocytes Podocyte Layer
     
     Testis (Reproductive System)
             Pre-Sertoli Cells Testis Cord
     
     Gonad
             XX Germ Cells Ovigerous Cord
     
     Kidney (Urinary System)
             Presumptive Podocytes Podocyte Layer
    MIS18BP1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MIS18BP1 Protein Expression
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    QuantiFast Probe-based Assays in human, mouse, rat MIS18BP1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MIS18BP1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for MIS18BP1 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mis18bp11 , 5 MIS18 binding protein 11, 5 72.96(n)1
    57.03(a)1
      12 (27.21 cM)5
    2176531  NM_172578.21  NP_766166.21 
     651327345 
    chicken
    (Gallus gallus)
    Aves MIS18BP16
    MIS18 binding protein 1
    30(a)
    1 ↔ 1
    5(58605377-58623023)
    lizard
    (Anolis carolinensis)
    Reptilia MIS18BP16
    MIS18 binding protein 1
    30(a)
    1 ↔ 1
    GL343274.1(154-23575)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.158852 Transcribed sequences 74.34(n)    AL873597.2 
    zebrafish
    (Danio rerio)
    Actinopterygii MIS18BP16
    MIS18 binding protein 1
    20(a)
    1 ↔ 1
    17(28670856-28682470) ENSDARG00000042563


    ENSEMBL Gene Tree for MIS18BP1 (if available)
    TreeFam Gene Tree for MIS18BP1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for MIS18BP1 (see all 1104)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2008478181,2
    --45671899(+) CGGCA-/TTTTTT 1 -- int10--------
    rs1179663231,2
    C,F--45671944(+) ATTCTA/GTATCC 1 -- int11Minor allele frequency- G:0.04NA 120
    rs1900195831,2
    --45671972(+) CAGAAA/GTAATC 1 -- int10--------
    rs1489074681,2
    --45671981(+) TCATGA/GTAGTT 1 -- int10--------
    rs1426028571,2
    --45672001(+) AATTAC/TCTTAG 1 -- int10--------
    rs2010880211,2
    C--45672039(+) TTCCG-/TTAAGT 1 -- int10--------
    rs781864451,2
    C,F--45672112(+) GAGTCT/GCTGTT 1 -- int12Minor allele frequency- G:0.04WA NA 238
    rs2022055431,2
    C--45672333(+) CAGTC-/ATGATTTG 1 -- int10--------
    rs1146051531,2
    F--45672336(+) TCATGA/TTTTGT 1 -- int11Minor allele frequency- T:0.06WA 118
    rs1814460181,2
    --45672358(+) TCATCC/GAGTAA 1 -- int10--------

    HapMap Linkage Disequilibrium report for MIS18BP1 (45672393 - 45722743 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10 variations for MIS18BP1:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2748678CNV Deletion23290073
    esv2748677CNV Deletion23290073
    nsv901842CNV Loss21882294
    nsv832785CNV Loss17160897
    nsv901841CNV Loss21882294
    nsv901846CNV Loss21882294
    nsv901845CNV Loss21882294
    nsv901844CNV Loss21882294
    nsv901843CNV Gain21882294
    dgv631e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MIS18BP1 gene, integrated from 10 sources (see all 26):
    (articles sorted by number of sources associating them with MIS18BP1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Functional genomics identifies a Myb domain-containing protein family required for assembly of CENP-A chromatin. (PubMed id 17339379)1, 2, 3 Maddox P.S.... Desai A. (J. Cell Biol. 2007)
    2. Priming of centromere for CENP-A recruitment by human hMis18alpha, hMis18beta, and M18BP1. (PubMed id 17199038)1, 2, 3 Fujita Y....Yanagida M. (Dev. Cell 2007)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins. (PubMed id 11572484)1, 2 Nagase T.... Ohara O. (DNA Res. 2001)
    6. A set of proteins interacting with transcription factor Sp1 identified in a two-hybrid screening. (PubMed id 10976766)1, 2 Gunther M.... Brison O. (Mol. Cell. Biochem. 2000)
    7. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    8. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    9. CENP-C facilitates the recruitment of M18BP1 to centromeric chromatin. (PubMed id 22540025)1 Dambacher S....Schotta G. (Nucleus 2012)
    10. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55320 HGNC: 20190 AceView: C14orf106 Ensembl:ENSG00000129534 euGenes: HUgn55320
    ECgene: MIS18BP1 H-InvDB: MIS18BP1

    (According to HUGE)
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    HUGE: KIAA1903

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for MIS18BP1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for MIS18BP1 gene:
    Search GeneIP for patents involving MIS18BP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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