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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MIS12 Gene

protein-coding   GIFtS: 50
GCID: GC17P005390

MIS12, MIND kinetochore complex component, homolog (S. pombe)

(Previous names: MIS12, MIND kinetochore complex component, homolog (yeast)...)
  Search for MIS12
in our new
 Human Malady Compendium 
Biological research products
for MIS12
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
MIS12, MIND Kinetochore Complex Component, Homolog (S. Pombe)1 2     2510025F08Rik2
KNTC2AP1 2     HMis121
MTW11 2     Homolog Of Yeast Mis122
MGC24881     MIS12 Homolog2
HMIS121     Protein MIS12 Homolog2
MIS12, MIND Kinetochore Complex Component, Homolog (Yeast)1     

External Ids:    HGNC: 249671   Entrez Gene: 790032   Ensembl: ENSG000001678427   OMIM: 6091785   UniProtKB: Q9H0813   

Export aliases for MIS12 gene to outside databases

Previous GC identifers: GC17P005727 GC17P005334 GC17P005590 GC17P005330 GC17P005280


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: MIS12_HUMAN, Q9H081
Function: Part of the MIS12 complex which is required for normal chromosome alignment and segregation and for
kinetochore formation during mitosis

Gene Wiki entry for MIS12


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NC_018928.1  NT_010718.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MIS12 gene promoter:
         HOXA3   SREBP-1c   HNF-3beta   YY1   SREBP-1b   CREB   SREBP-1a   HSF2   deltaCREB   MRF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): MIS12 promoter sequence
   Search SABiosciences Chromatin IP Primers for MIS12

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MIS12


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17p13.2   Ensembl cytogenetic band:  17p13.2   HGNC cytogenetic band: 17p13.3

MIS12 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MIS12 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P005390:  view genomic region     (about GC identifiers)

Start:
5,389,605 bp from pter      End:
5,394,134 bp from pter
Size:
4,530 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: MIS12_HUMAN, Q9H081 (See protein sequence)
Recommended Name: Protein MIS12 homolog  
Size: 205 amino acids; 24140 Da
Subunit: Component of the MIS12 complex composed of MIS12, DSN1, NSL1 and PMF1. Also interacts with CASC5, CBX3, CBX5,
NDC80 and ZWINT
Subcellular location: Nucleus. Chromosome, centromere, kinetochore. Note=Associated with the kinetochore
Sequence caution: Sequence=AK056072; Type=Frameshift; Positions=147;
Secondary accessions: Q96N24

Explore the universe of human proteins at neXtProt for MIS12: NX_Q9H081

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9H081

  • MIS12 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (5 alternative transcripts): 
    NP_001245146.1  NP_001245147.1  NP_001245148.1  NP_001245149.1  NP_076944.1  

    ENSEMBL proteins: 
     ENSP00000461333   ENSP00000459366   ENSP00000461252   ENSP00000370557  
    Reactome Protein details: Q9H081
    Human Recombinant Protein Products: 
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    Novus Biologicals MIS12 Proteins
    Novus Biologicals MIS12 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for MIS12

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000444MIS12/MIND type complex IDA16585270
    GO:0000775chromosome, centromeric region ----
    GO:0005634nucleus IDA--
    GO:0005829cytosol TAS--


    MIS12 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for MIS12


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    MIS12 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR008685 Centromere_Mis12

    Graphical View of Domain Structure for InterPro Entry Q9H081

    ProtoNet protein and cluster: Q9H081

    UniProtKB/Swiss-Prot: MIS12_HUMAN, Q9H081
    Similarity: Belongs to the mis12 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: MIS12_HUMAN, Q9H081
    Function: Part of the MIS12 complex which is required for normal chromosome alignment and segregation and for
    kinetochore formation during mitosis

    miRNA
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    miRTarBase miRNAs that target MIS12:
    hsa-mir-192 (MIRT004855)

    OriGene 3'-UTR Clone: MIS12
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MIS12
    8/11 QIAGEN miScript miRNA Assays for microRNAs that regulate MIS12 (see all 11):
    hsa-miR-30c hsa-miR-30d hsa-miR-3617 hsa-miR-138-2* hsa-miR-7 hsa-miR-30a hsa-miR-641 hsa-miR-629*
    SwitchGear 3'UTR luciferase reporter plasmidMIS12 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MIS12 (see all 7)
    OriGene shRNA RFP: MIS12
    OriGene siRNA: MIS12
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MIS12

    Gene Editing
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    Clone
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MIS12

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI15502821


    MIS12 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for MIS12:
     Proliferating cells 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1M Phase
    M Phase1.00
    Mitotic Anaphase0.85
    Mitotic M-M/G1 phases0.88
    Separation of Sister Chromatids0.80
    Mitotic Metaphase and Anaphase0.85
    2Resolution of Sister Chromatid Cohesion
    Resolution of Sister Chromatid Cohesion1.00
    Mitotic Prometaphase0.93
    Kinetochore assembly0.96
    3Cell Cycle
    Cell Cycle1.00
    Cell Cycle, Mitotic0.84

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    5/10        Reactome Pathways for MIS12 (see all 10)
        Mitotic Metaphase and Anaphase
    Mitotic Prometaphase
    Resolution of Sister Chromatid Cohesion
    Mitotic Anaphase
    Cell Cycle



    MIS12 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for MIS12

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/95 Interacting proteins for MIS12 (Q9H0813 ENSP000003705574) via UniProtKB, MINT, STRING, and/or I2D (see all 95)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DSN1Q9H4103, ENSP000003628504I2D: score=4 STRING: ENSP00000362850
    ZWINTO952293, ENSP000003630554I2D: score=4 STRING: ENSP00000363055
    CASC5Q8NG313, ENSP000003354634I2D: score=3 STRING: ENSP00000335463
    FGAP026713, ENSP000003063614I2D: score=2 STRING: ENSP00000306361
    FGBP026753, ENSP000003060994I2D: score=2 STRING: ENSP00000306099
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000087M phase of mitotic cell cycle TAS--
    GO:0000236mitotic prometaphase TAS--
    GO:0000278mitotic cell cycle TAS--
    GO:0007059chromosome segregation IMP16585270
    GO:0007067mitosis ----


    MIS12 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MIS12
    Search CenterWatch for drugs/clinical trials and news about MIS12 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for MIS12 gene (5 alternative transcripts): 
    NM_001258217.1  NM_001258218.1  NM_001258219.1  NM_001258220.1  NM_024039.2  

    Unigene Cluster for MIS12:

    MIS12, MIND kinetochore complex component, homolog (S. pombe)
    Hs.267194  [show with all ESTs]
    Unigene Representative Sequence: NM_001258217
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000576988 ENST00000576570 ENST00000573759(uc002gcd.3) ENST00000574186
    ENST00000381165(uc002gce.3)

    miRNA
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    8/11 QIAGEN miScript miRNA Assays for microRNAs that regulate MIS12 (see all 11):
    hsa-miR-30c hsa-miR-30d hsa-miR-3617 hsa-miR-138-2* hsa-miR-7 hsa-miR-30a hsa-miR-641 hsa-miR-629*
    SwitchGear 3'UTR luciferase reporter plasmidMIS12 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MIS12 (see all 7)
    OriGene shRNA RFP: MIS12
    OriGene siRNA: MIS12
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    Clone
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MIS12
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MIS12

    Additional cDNA sequence: 

    AK056072.1 AK289939.1 AL136906.1 BC000229.1 CR533460.1 

    8 DOTS entries:

    DT.91947548  DT.100686000  DT.95082079  DT.97789599  DT.120915538  DT.97772191  DT.120915539  DT.120915568 

    24/137 AceView cDNA sequences (see all 137):

    AI469551 AI912461 AL136906 AI652652 AI024420 CR533460 BG058769 BF439391 
    AI582012 CK300602 AA417097 AA496666 AI075913 AI686983 CR617671 NM_024039 
    AA902903 BQ184651 F10309 BI837978 CA308473 CB139315 CA309471 AL712113 

    GeneLoc Exon Structure

    5/9 Alternative Splicing Database (ASD) splice patterns (SP) for MIS12 (see all 9)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b · 3c · 3d · 3e ^ 4a · 4b ^ 5a · 5b · 5c ^ 6a · 6b ^ 7a · 7b · 7c · 7d · 7e
    SP1:                          -     -     -     -     -     -     -                                                               
    SP2:              -     -     -     -     -     -     -     -     -     -     -     -                                             
    SP3:                          -     -     -     -     -     -     -     -     -     -                                             
    SP4:                                                  -     -     -     -     -     -                                             
    SP5:                          -     -     -     -     -     -     -     -     -     -     -     -                                 


    ECgene alternative splicing isoforms for MIS12

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MIS12 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AAATATGTTT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See MIS12 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MIS12

    SOURCE GeneReport for Unigene cluster: Hs.267194
        SABiosciences Custom PCR Arrays for MIS12
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MIS12

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for MIS12 gene from 4/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mis121 , 5 MIS12 homolog (yeast)1, 5 83.58(n)1
    79.31(a)1
      11 (43.21 cM)5
    671391  NM_025993.21  NP_080269.11 
     710196115 
    chicken
    (Gallus gallus)
    Aves MIS121 MIS12, MIND kinetochore complex component, homolog more 61.9(n)
    60.59(a)
      693254  NM_001044677.1  NP_001038142.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    --
    37(a)
    35(a)
    many → 1
    many → 1
    2(191809880-191810494)
    1(193607259-193610479)
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:641161 zgc:64116 50.69(n)
    39.58(a)
      393349  NM_200378.1  NP_956672.1 


    ENSEMBL Gene Tree for MIS12 (if available)
    TreeFam Gene Tree for MIS12 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/73 NCBI SNPs in MIS12 are shown (see all 73    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1414567431,2
    --5391550(+) GGACAC/TTGGCA 5 -- int1 ut510--------
    rs1508602451,2
    --5391557(+) GGCAAC/TGGAGT 5 -- ut51 int10--------
    rs739738051,2
    C,F,--5391579(+) TAGATC/TATGAG 5 -- ut51 int13Minor allele frequency- T:0.06WA CSA 122
    rs23093991,2
    C,F,A,H,--5391690(+) ATATGA/GGTAAG 5 -- ut51 int1 ese331Minor allele frequency- G:0.22NS EA NA WA CSA 2913
    rs1393141601,2
    --5391711(+) ATTGTA/GTAGGA 5 -- int1 ut510--------
    rs1847389631,2
    --5391823(+) TGAGTC/TTCTAG 5 -- int1 ut510--------
    rs58190281,2
    C,F,--5391979(+) GAGGC-/AAAGAG 5 -- int15Minor allele frequency- A:0.29NA CSA 14
    rs1427345071,2
    --5392073(+) TCTGTA/TATGTG 5 -- int10--------
    rs1898042091,2
    C,--5392152(+) TTCACG/AACTGA 5 -- ut511Minor allele frequency- A:0.00EU 1321
    rs9292611,2
    C,F,A,H,--5392161(+) GAAAAC/TAACAT 5 -- ut5130Minor allele frequency- T:0.33EA NS NA WA CSA EU 5081

    HapMap Linkage Disequilibrium report for MIS12 (5389605 - 5394134 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for MIS12: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MIS12
    DNA2.0 Custom Variant and Variant Library Synthesis for MIS12

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    MIS12 for disorders           About MalaCards

    MIS12 for disorders           About GeneDecksing

    OMIM gene information: 609178    OMIM disorders: --

    1 disease from the University of Copenhagen DISEASES database for MIS12:
    Microcephaly

    Export disorders for MIS12 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MIS12 gene, integrated from 9 sources (see all 30):
    (articles sorted by number of sources associating them with MIS12)
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    1. Human centromere chromatin protein hMis12, essential for equal segregation, is independent of CENP-A loading pathway. (PubMed id 12515822)1, 2, 3 Goshima G....Yanagida M. (2003)
    2. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2, 3 Wiemann S.... Poustka A. (2001)
    3. The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation. (PubMed id 16585270)1, 2 Kline S.L.... Desai A. (2006)
    4. A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1. (PubMed id 15502821)1, 2 Obuse C....Yanagida M. (2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    7. Aurora B controls kinetochore-microtubule attachments by inhibiting Ska complex-KMN network interaction. (PubMed id 22371557)1 Chan Y.W....Santamaria A. (2012)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    9. Protein interaction domain mapping of human kinetocho re protein Blinkin reveals a consensus motif for binding of spindle assembly ch eckpoint proteins Bub1 and BubR1. (PubMed id 21199919)1 Kiyomitsu T....Yanagida M. (2011)
    10. Direct binding of Cenp-C to the Mis12 complex joins t he inner and outer kinetochore. (PubMed id 21353556)1 Screpanti E....Musacchio A. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79003 HGNC: 24967 AceView: MIS12 Ensembl:ENSG00000167842 euGenes: HUgn79003
    ECgene: MIS12 H-InvDB: MIS12

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MIS12 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for MIS12 gene:
    Search GeneIP for patents involving MIS12

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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