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Aliases for MIRLET7F2 Gene

Subcategory (RNA class) for MIRLET7F2 Gene


Quality Score for this RNA gene is


Aliases for MIRLET7F2 Gene

  • MicroRNA Let-7f-2 2 3
  • Hsa-Let-7f-2 3
  • MIRNLET7F2 3
  • Let-7f-2 3
  • LET7F2 3

External Ids for MIRLET7F2 Gene

Previous HGNC Symbols for MIRLET7F2 Gene


Summaries for MIRLET7F2 Gene

Entrez Gene Summary for MIRLET7F2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIRLET7F2 Gene

MIRLET7F2 (MicroRNA Let-7f-2) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIRLET7F2 Gene

Genomics for MIRLET7F2 Gene

Genomic Location for MIRLET7F2 Gene

53,557,192 bp from pter
53,557,274 bp from pter
83 bases
Minus strand

Genomic View for MIRLET7F2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIRLET7F2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIRLET7F2 Gene

No data available for Regulatory Elements for MIRLET7F2 Gene

Proteins for MIRLET7F2 Gene

Post-translational modifications for MIRLET7F2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIRLET7F2 Gene

Domains & Families for MIRLET7F2 Gene

Gene Families for MIRLET7F2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIRLET7F2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIRLET7F2 Gene

Function for MIRLET7F2 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIRLET7F2 Gene

Localization for MIRLET7F2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIRLET7F2 Gene

Pathways & Interactions for MIRLET7F2 Gene

SuperPathways for MIRLET7F2 Gene

Superpath Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIRLET7F2: view

Pathways by source for MIRLET7F2 Gene

1 KEGG pathway for MIRLET7F2 Gene

Interacting Proteins for MIRLET7F2 Gene

Gene Ontology (GO) - Biological Process for MIRLET7F2 Gene


No data available for SIGNOR curated interactions for MIRLET7F2 Gene

Drugs & Compounds for MIRLET7F2 Gene

No Compound Related Data Available

Transcripts for MIRLET7F2 Gene

mRNA/cDNA for MIRLET7F2 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIRLET7F2 Gene

No ASD Table

Relevant External Links for MIRLET7F2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIRLET7F2 Gene

mRNA expression in normal human tissues for MIRLET7F2 Gene

genes like me logo Genes that share expression patterns with MIRLET7F2: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIRLET7F2 Gene

Orthologs for MIRLET7F2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIRLET7F2 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia bta-let-7f-2 36
  • 100 (a)
(Canis familiaris)
Mammalia -- 36
  • 100 (a)
(Monodelphis domestica)
Mammalia mdo-let-7f-2 36
  • 94 (a)
(Mus musculus)
Mammalia Mirlet7f-2 36
  • 100 (a)
(Ornithorhynchus anatinus)
Mammalia oan-let-7f-2 36
  • 59 (a)
(Pan troglodytes)
Mammalia ptr-let-7f-2 36
  • 100 (a)
(Gallus gallus)
Aves gga-let-7a-1 36
  • 83 (a)
(Anolis carolinensis)
Reptilia aca-let-7f-1 36
  • 78 (a)
(Danio rerio)
Actinopterygii dre-let-7a-1 36
  • 76 (a)
Species with no ortholog for MIRLET7F2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIRLET7F2 Gene

Gene Tree for MIRLET7F2 (if available)
Gene Tree for MIRLET7F2 (if available)

Paralogs for MIRLET7F2 Gene

No data available for Paralogs for MIRLET7F2 Gene

Variants for MIRLET7F2 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIRLET7F2 Gene

Variant ID Type Subtype PubMed ID
nsv435891 CNV Deletion 17901297
esv2740175 CNV Deletion 23290073

Relevant External Links for MIRLET7F2 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIRLET7F2 Gene

Disorders for MIRLET7F2 Gene

Relevant External Links for MIRLET7F2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with MIRLET7F2: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIRLET7F2 Gene

Publications for MIRLET7F2 Gene

  1. Circulating microRNAs as potential biomarkers for endometriosis. (PMID: 25772772) Cho S. … Taylor H.S. (Fertil. Steril. 2015) 67
  2. Plasma miRNAs as Diagnostic and Prognostic Biomarkers for Ovarian Cancer. (PMID: 24223734) Zheng H. … Chen K. (PLoS ONE 2013) 67
  3. IL-23 receptor regulation by Let-7f in human CD4+ memory T cells. (PMID: 21508257) Li Z. … Kwon J.H. (J. Immunol. 2011) 67
  4. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 67
  5. Analysis of deep sequencing microRNA expression profile from human embryonic stem cells derived mesenchymal stem cells reveals possible role of let-7 microRNA family in downstream targeting of hepatic nuclear factor 4 alpha. (PMID: 20158877) Koh W. … Tanavde V. (BMC Genomics 2010) 67

Products for MIRLET7F2 Gene

Sources for MIRLET7F2 Gene

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