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Aliases for MIRLET7F1 Gene

Subcategory (RNA class) for MIRLET7F1 Gene


Quality Score for this RNA gene is


Aliases for MIRLET7F1 Gene

  • MicroRNA Let-7f-1 2 3
  • MIRNLET7F1 3 6
  • LET7F1 3 6
  • Hsa-Let-7f-1 3
  • Let-7f-1 3

External Ids for MIRLET7F1 Gene

ORGUL Members for MIRLET7F1 Gene

Previous HGNC Symbols for MIRLET7F1 Gene


Previous GeneCards Identifiers for MIRLET7F1 Gene

  • GC09P095983
  • GC09P096939
  • GC09P096943
  • GC09P096945
  • GC09P096951
  • GC09P096956

Summaries for MIRLET7F1 Gene

Entrez Gene Summary for MIRLET7F1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIRLET7F1 Gene

MIRLET7F1 (MicroRNA Let-7f-1) is an RNA Gene, and is affiliated with the undefined RNA class. Among its related pathways are MicroRNAs in cancer and miRNAs involved in DDR.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIRLET7F1 Gene

Genomics for MIRLET7F1 Gene

Genomic Location for MIRLET7F1 Gene

94,176,333 bp from pter
94,176,442 bp from pter
110 bases
Plus strand

Genomic View for MIRLET7F1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIRLET7F1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIRLET7F1 Gene

No data available for Regulatory Elements for MIRLET7F1 Gene

Proteins for MIRLET7F1 Gene

Post-translational modifications for MIRLET7F1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIRLET7F1 Gene

Domains for MIRLET7F1 Gene

Gene Families for MIRLET7F1 Gene

  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIRLET7F1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIRLET7F1 Gene

Function for MIRLET7F1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIRLET7F1 Gene

Localization for MIRLET7F1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIRLET7F1 Gene

Pathways for MIRLET7F1 Gene

genes like me logo Genes that share pathways with MIRLET7F1: view

Pathways by source for MIRLET7F1 Gene

1 BioSystems pathway for MIRLET7F1 Gene
1 KEGG pathway for MIRLET7F1 Gene

Interacting Proteins for MIRLET7F1 Gene

Gene Ontology (GO) - Biological Process for MIRLET7F1 Gene


Transcripts for MIRLET7F1 Gene

mRNA/cDNA for MIRLET7F1 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIRLET7F1 Gene

No ASD Table

Relevant External Links for MIRLET7F1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIRLET7F1 Gene

mRNA expression in normal human tissues for MIRLET7F1 Gene

genes like me logo Genes that share expressions with MIRLET7F1: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIRLET7F1 Gene

Orthologs for MIRLET7F1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIRLET7F1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia bta-let-7f-1 36
  • 100 (a)
(Canis familiaris)
Mammalia cfa-let-7f 36
  • 100 (a)
(Monodelphis domestica)
Mammalia mdo-let-7f-1 36
  • 100 (a)
(Mus musculus)
Mammalia Gm24111 36
  • 52 (a)
(Ornithorhynchus anatinus)
Mammalia oan-let-7e 36
  • 46 (a)
(Pan troglodytes)
Mammalia ptr-let-7f-1 36
  • 100 (a)
(Gallus gallus)
Aves gga-let-7f 36
  • 88 (a)
(Anolis carolinensis)
Reptilia aca-let-7f-2 36
  • 54 (a)
(Danio rerio)
Actinopterygii dre-let-7f 36
  • 66 (a)
Species with no ortholog for MIRLET7F1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIRLET7F1 Gene

Gene Tree for MIRLET7F1 (if available)
Gene Tree for MIRLET7F1 (if available)

Paralogs for MIRLET7F1 Gene

No data available for Paralogs for MIRLET7F1 Gene

Variants for MIRLET7F1 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIRLET7F1 Gene

Variant ID Type Subtype PubMed ID
nsv831655 CNV Gain 17160897

Relevant External Links for MIRLET7F1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for MIRLET7F1 Gene

Disorders for MIRLET7F1 Gene

No disorders were found for MIRLET7F1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MIRLET7F1 Gene

Publications for MIRLET7F1 Gene

  1. Identification of novel genes coding for small expressed RNAs. (PMID: 11679670) Lagos-Quintana M. … Tuschl T. (Science 2001) 3
  2. Reduced accumulation of specific microRNAs in colorectal neoplasia. (PMID: 14573789) Michael M.Z. … James R.J. (Mol. Cancer Res. 2003) 3
  3. Altered expression profiles of microRNAs during TPA-induced differentiation of HL-60 cells. (PMID: 15325244) Kasashima K. … Kozu T. (Biochem. Biophys. Res. Commun. 2004) 3
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  5. The tumor suppressor microRNA let-7 represses the HMGA2 oncogene. (PMID: 17437991) Lee Y.S. … Dutta A. (Genes Dev. 2007) 3

Products for MIRLET7F1 Gene

Sources for MIRLET7F1 Gene

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