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Aliases for MIR99B Gene

Subcategory (RNA class) for MIR99B Gene


Quality Score for this RNA gene is


Aliases for MIR99B Gene

  • MicroRNA 99b 2 3
  • Hsa-Mir-99b 3
  • Mir-99b 3
  • MIRN99B 3

External Ids for MIR99B Gene

ORGUL Members for MIR99B Gene

Previous HGNC Symbols for MIR99B Gene

  • MIRN99B

Previous GeneCards Identifiers for MIR99B Gene

  • GC19P056922
  • GC19P056926
  • GC19P052195

Summaries for MIR99B Gene

Entrez Gene Summary for MIR99B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR99B Gene

MIR99B (MicroRNA 99b) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR99B Gene

Genomics for MIR99B Gene

Genomic Location for MIR99B Gene

51,692,612 bp from pter
51,692,681 bp from pter
70 bases
Plus strand

Genomic View for MIR99B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR99B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR99B Gene

No data available for Regulatory Elements for MIR99B Gene

Proteins for MIR99B Gene

Post-translational modifications for MIR99B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR99B Gene

Domains & Families for MIR99B Gene

Gene Families for MIR99B Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR99B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR99B Gene

Function for MIR99B Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR99B Gene

Localization for MIR99B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR99B Gene

Pathways & Interactions for MIR99B Gene

SuperPathways for MIR99B Gene

No Data Available

Interacting Proteins for MIR99B Gene

Gene Ontology (GO) - Biological Process for MIR99B Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR99B Gene

Drugs & Compounds for MIR99B Gene

No Compound Related Data Available

Transcripts for MIR99B Gene

mRNA/cDNA for MIR99B Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR99B Gene

No ASD Table

Relevant External Links for MIR99B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR99B Gene

No Expression Related Data Available

Primer Products

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR99B Gene

Orthologs for MIR99B Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR99B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia bta-mir-99b 36
  • 100 (a)
(Canis familiaris)
Mammalia cfa-mir-99b 36
  • 95 (a)
(Monodelphis domestica)
Mammalia mdo-mir-10a 36
  • 42 (a)
(Mus musculus)
Mammalia Mir99b 36
  • 100 (a)
(Ornithorhynchus anatinus)
Mammalia oan-mir-100 36
  • 60 (a)
(Pan troglodytes)
Mammalia ptr-mir-99b 36
  • 100 (a)
(Gallus gallus)
Aves gga-mir-100 36
  • 59 (a)
(Anolis carolinensis)
Reptilia aca-mir-99b 36
  • 60 (a)
(Danio rerio)
Actinopterygii dre-mir-10d 36
  • 28 (a)
Species with no ortholog for MIR99B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR99B Gene

Gene Tree for MIR99B (if available)
Gene Tree for MIR99B (if available)

Paralogs for MIR99B Gene

No data available for Paralogs for MIR99B Gene

Variants for MIR99B Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR99B Gene

Variant ID Type Subtype PubMed ID
dgv1109e1 CNV Complex 17122850
esv638 CNV CNV 17122850
dgv1110e1 CNV Complex 17122850
nsv912296 CNV Loss 21882294
nsv9742 CNV Gain+Loss 18304495

Relevant External Links for MIR99B Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR99B Gene

Disorders for MIR99B Gene

Relevant External Links for MIR99B

Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with MIR99B: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR99B Gene

Publications for MIR99B Gene

  1. miR-99a and -99b inhibit cervical cancer cell proliferation and invasion by targeting mTOR signaling pathway. (PMID: 24668416) Wang L. … Li M. (Med. Oncol. 2014) 67
  2. MicroRNA-99 family targets AKT/mTOR signaling pathway in dermal wound healing. (PMID: 23724047) Jin Y. … Zhou X. (PLoS ONE 2013) 67
  3. miR-99b-targeted mTOR induction contributes to irradiation resistance in pancreatic cancer. (PMID: 23886294) Wei F. … Lu Z. (Mol. Cancer 2013) 67
  4. Role of microRNAs 99b, 181a, and 181b in the differentiation of human embryonic stem cells to vascular endothelial cells. (PMID: 22232059) Kane N.M. … Baker A.H. (Stem Cells 2012) 67
  5. miR-99 family of MicroRNAs suppresses the expression of prostate-specific antigen and prostate cancer cell proliferation. (PMID: 21212412) Sun D. … Dutta A. (Cancer Res. 2011) 67

Products for MIR99B Gene

Sources for MIR99B Gene

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