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Aliases for MIR98 Gene

Subcategory (RNA class) for MIR98 Gene


Quality Score for this RNA gene is


Aliases for MIR98 Gene

  • MicroRNA 98 2 3 5
  • Hsa-Mir-98 3
  • MiR-98 3
  • MIRN98 3

External Ids for MIR98 Gene

Previous HGNC Symbols for MIR98 Gene

  • MIRN98

Previous GeneCards Identifiers for MIR98 Gene

  • GC0XM053601
  • GC0XM053589
  • GC0XM053592
  • GC0XM053561
  • GC0XM053562
  • GC0XM053563
  • GC0XM053565

Summaries for MIR98 Gene

Entrez Gene Summary for MIR98 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR98 Gene

MIR98 (MicroRNA 98) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Toll-like receptor signaling pathway.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR98 Gene

Genomics for MIR98 Gene

Genomic Location for MIR98 Gene

53,556,223 bp from pter
53,556,341 bp from pter
119 bases
Minus strand

Genomic View for MIR98 Gene

Genes around MIR98 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR98 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR98 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR98 Gene

No data available for Regulatory Elements for MIR98 Gene

Proteins for MIR98 Gene

Post-translational modifications for MIR98 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR98 Gene

Domains & Families for MIR98 Gene

Gene Families for MIR98 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR98: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR98 Gene

Function for MIR98 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR98 Gene

Localization for MIR98 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR98 Gene

Pathways & Interactions for MIR98 Gene

genes like me logo Genes that share pathways with MIR98: view

Pathways by source for MIR98 Gene

1 BioSystems pathway for MIR98 Gene

Interacting Proteins for MIR98 Gene

Gene Ontology (GO) - Biological Process for MIR98 Gene


No data available for SIGNOR curated interactions for MIR98 Gene

Transcripts for MIR98 Gene

mRNA/cDNA for MIR98 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR98 Gene

No ASD Table

Relevant External Links for MIR98 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR98 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR98 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR98 Gene:

genes like me logo Genes that share expression patterns with MIR98: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR98 Gene

Orthologs for MIR98 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR98 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ptr-mir-98 35
  • 100 (a)
(Canis familiaris)
Mammalia cfa-mir-98 35
  • 96 (a)
(Bos Taurus)
Mammalia bta-mir-98 35
  • 94 (a)
(Mus musculus)
Mammalia Mir98 35
  • 81 (a)
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 56 (a)
oan-mir-98 35
  • 55 (a)
(Gallus gallus)
Aves gga-let-7a-3 35
  • 74 (a)
(Anolis carolinensis)
Reptilia aca-mir-98 35
  • 88 (a)
(Danio rerio)
Actinopterygii dre-let-7h 35
  • 62 (a)
Species where no ortholog for MIR98 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR98 Gene

Gene Tree for MIR98 (if available)
Gene Tree for MIR98 (if available)

Paralogs for MIR98 Gene

No data available for Paralogs for MIR98 Gene

Variants for MIR98 Gene

Sequence variations from dbSNP and Humsavar for MIR98 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs142245454 -- 53,555,932(+) ACCAC(C/T)GCGCC intron-variant, downstream-variant-500B
rs148189854 -- 53,556,127(+) ACACC(A/G)TCTGT intron-variant, downstream-variant-500B
rs17276588 -- 53,557,457(+) TGTGG(A/G)ACTTT intron-variant, upstream-variant-2KB
rs182424200 -- 53,558,296(+) CCACA(C/T)TGGCA intron-variant, upstream-variant-2KB
rs184393650 -- 53,556,750(+) AAAAA(A/G)GAACA intron-variant, downstream-variant-500B, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR98 Gene

Variant ID Type Subtype PubMed ID
esv2740175 CNV deletion 23290073
esv3576879 CNV gain 25503493
nsv435891 CNV deletion 17901297

Relevant External Links for MIR98 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR98 Gene

Disorders for MIR98 Gene

Relevant External Links for MIR98

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR98 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR98 Gene

Publications for MIR98 Gene

  1. Dysregulated miR-98 Contributes to Extracellular Matrix Degradation by Targeting IL-6/STAT3 Signaling Pathway in Human Intervertebral Disc Degeneration. (PMID: 26587789) Ji M.L. … Wang C. (J. Bone Miner. Res. 2016) 3 64
  2. Peroxisome Proliferator-Activated Receptor I^ and microRNA 98 in Hypoxia-Induced Endothelin-1 Signaling. (PMID: 26098770) Kang B.Y. … Hart C.M. (Am. J. Respir. Cell Mol. Biol. 2016) 3 64
  3. miR-98 delays skeletal muscle differentiation by down-regulating E2F5. (PMID: 25422988) Kropp J. … Polesskaya A. (Biochem. J. 2015) 3 64
  4. miR-98 protects endothelial cells against hypoxia/reoxygenation induced-apoptosis by targeting caspase-3. (PMID: 26367177) Li H.W. … Yu G. (Biochem. Biophys. Res. Commun. 2015) 3 64
  5. Overexpression of miR-98 inhibits cell invasion in glioma cell lines via downregulation of IKKI/. (PMID: 26502849) Fan Y.H. … Zhu X.G. (Eur Rev Med Pharmacol Sci 2015) 3 64

Products for MIR98 Gene

Sources for MIR98 Gene

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