Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR95 Gene

Subcategory (RNA class) for MIR95 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR95 Gene

  • MicroRNA 95 2 3 5
  • Hsa-Mir-95 3
  • MiR-95 3
  • MIRN95 3

External Ids for MIR95 Gene

Previous HGNC Symbols for MIR95 Gene

  • MIRN95

Previous GeneCards Identifiers for MIR95 Gene

  • GC04M008057

Summaries for MIR95 Gene

Entrez Gene Summary for MIR95 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR95 Gene

MIR95 (MicroRNA 95) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins..

Additional gene information for MIR95 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR95 Gene

Genomics for MIR95 Gene

GeneHancer (GH) Regulatory Elements for MIR95 Gene

Promoters and enhancers for MIR95 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH04I008003 Enhancer 0.6 dbSUPER 550.8 -0.6 -575 4.6 ESRRA ZNF687 CLOCK NFIB RARA ZKSCAN1 ZNF664 GATA3 POLR2A TARDBP MIR95 AFAP1 LOC389199 GC04M008013 ABLIM2
GH04I007999 Enhancer 0.5 dbSUPER 0.8 +4.2 4164 3.5 BCOR ZNF687 ZMYM3 REST ZIC2 PIR56008 MIR95 ABLIM2
GH04I008008 Enhancer 1 ENCODE dbSUPER 0.4 -5.0 -5014 2.8 PKNOX1 FOXA2 BMI1 RFX5 SCRT2 RCOR1 ZNF217 RFX3 GLIS1 RCOR2 AFAP1 LOC389199 ABLIM2 GC04M008013 MIR95
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR95 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR95 Gene

Genomic Locations for MIR95 Gene
chr4:8,005,301-8,005,381
(GRCh38/hg38)
Size:
81 bases
Orientation:
Minus strand
chr4:8,007,028-8,007,108
(GRCh37/hg19)

Genomic View for MIR95 Gene

Genes around MIR95 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR95 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR95 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR95 Gene

Proteins for MIR95 Gene

Post-translational modifications for MIR95 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR95 Gene

Domains & Families for MIR95 Gene

Gene Families for MIR95 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR95: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR95 Gene

Function for MIR95 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR95 Gene

Localization for MIR95 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR95 Gene

Pathways & Interactions for MIR95 Gene

genes like me logo Genes that share pathways with MIR95: view

Pathways by source for MIR95 Gene

1 BioSystems pathway for MIR95 Gene

Interacting Proteins for MIR95 Gene

Gene Ontology (GO) - Biological Process for MIR95 Gene

None

No data available for SIGNOR curated interactions for MIR95 Gene

Drugs & Compounds for MIR95 Gene

No Compound Related Data Available

Transcripts for MIR95 Gene

mRNA/cDNA for MIR95 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR95 Gene

No ASD Table

Relevant External Links for MIR95 Gene

GeneLoc Exon Structure for
MIR95
ECgene alternative splicing isoforms for
MIR95

Expression for MIR95 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR95 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR95 Gene:

MIR95
genes like me logo Genes that share expression patterns with MIR95: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR95 Gene

Orthologs for MIR95 Gene

Evolution for MIR95 Gene

ENSEMBL:
Gene Tree for MIR95 (if available)
TreeFam:
Gene Tree for MIR95 (if available)

No data available for Orthologs for MIR95 Gene

Paralogs for MIR95 Gene

No data available for Paralogs for MIR95 Gene

Variants for MIR95 Gene

Sequence variations from dbSNP and Humsavar for MIR95 Gene

SNP ID Clin Chr 04 pos Variation AA Info Type
rs1000186253 -- 8,006,182(-) G/A upstream_transcript_variant
rs1000793340 -- 8,006,982(-) G/A upstream_transcript_variant
rs1002561921 -- 8,005,621(-) G/T upstream_transcript_variant
rs1002809157 -- 8,005,227(-) T/A downstream_transcript_variant
rs1004450888 -- 8,006,235(-) C/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR95 Gene

Variant ID Type Subtype PubMed ID
esv34140 CNV loss 18971310
esv34196 OTHER inversion 12058347
nsv469779 CNV loss 16826518
nsv593623 CNV loss 21841781
nsv829851 CNV loss 17160897
nsv829852 CNV gain+loss 17160897

Additional Variant Information for MIR95 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR95

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR95 Gene

Disorders for MIR95 Gene

Additional Disease Information for MIR95

No disorders were found for MIR95 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR95 Gene

Publications for MIR95 Gene

  1. Examining the effect of gene reduction in miR-95 and enhanced radiosensitivity in non-small cell lung cancer. (PMID: 26915403) Ma W … Zhang YJ (Cancer gene therapy 2016) 3 58
  2. Abnormal Expression of miR-21 and miR-95 in Cancer Stem-Like Cells is Associated with Radioresistance of Lung Cancer. (PMID: 25831148) Zhang J … Chen Y (Cancer investigation 2015) 3 58
  3. Screening of differential microRNA expression in gastric signet ring cell carcinoma and gastric adenocarcinoma and target gene prediction. (PMID: 25964059) Chen J … Jiang L (Oncology reports 2015) 3 58
  4. Downregulation of miR-95-3p inhibits proliferation, and invasion promoting apoptosis of glioma cells by targeting CELF2. (PMID: 26165303) Fan B … Yang L (International journal of oncology 2015) 3 58
  5. Overexpression of microRNA-95-3p suppresses brain metastasis of lung adenocarcinoma through downregulation of cyclin D1. (PMID: 25971210) Hwang SJ … Kim HH (Oncotarget 2015) 3 58

Products for MIR95 Gene

Sources for MIR95 Gene

Content
Loading form....