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Aliases for MIR940 Gene

Subcategory (RNA class) for MIR940 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR940 Gene

  • MicroRNA 940 2 3 5
  • Hsa-Mir-940 3
  • Mir-940 3
  • MIRN940 3

External Ids for MIR940 Gene

Previous HGNC Symbols for MIR940 Gene

  • MIRN940

Previous GeneCards Identifiers for MIR940 Gene

  • GC16P002263
  • GC16P002321

Summaries for MIR940 Gene

Entrez Gene Summary for MIR940 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR940 Gene

MIR940 (MicroRNA 940) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR940 include Tetralogy Of Fallot.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR940 Gene

Genomics for MIR940 Gene

Regulatory Elements for MIR940 Gene

Enhancers for MIR940 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH16F002816 1.2 ENCODE 23.4 +549.4 549372 1.7 MLX CREB3L1 ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 ZNF766 CBX5 MIR940 ZNF263 ZNF597 ZNF213-AS1 ENSG00000200059 ENSG00000261240 ZNF598 THOC6 ENSG00000255513 SNORA64
GH16F002968 1.2 ENCODE 14.5 +701.6 701591 3.4 HDGF MLX ZFP64 ARID4B SIN3A DMAP1 ZNF2 SLC30A9 ZNF143 ZNF416 ZNF263 ZNF597 SNHG19 SNORD60 ERVK13-1 CLUAP1 CREBBP LOC107984895 ZNF205 ZNF174
GH16F002266 1.2 ENCODE 13.2 +0.1 57 3.2 HDGF PKNOX1 ARNT CREB3L1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 ENSG00000260646 ZNF205 ENSG00000226890 ENSG00000200059 ENSG00000261240 ENSG00000261123 MIR940 RNPS1 LOC105371049 IFT140
GH16F002867 1.2 ENCODE 10.8 +600.3 600322 2.0 CREB3L1 MLX WRNIP1 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF207 ZNF143 LOC101929566 ZNF263 ZNF597 ZNF213-AS1 ENSG00000200059 ENSG00000261240 ZNF598 THOC6 ENSG00000255513 FLYWCH2
GH16F002211 1.1 ENCODE 11 -53.8 -53835 5.1 HDGF PKNOX1 CREB3L1 MLX ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 PGP BRICD5 ZNF213-AS1 NME3 EME2 IFT140 MIR940 HN1L SNHG19 ENSG00000260051
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR940 on UCSC Golden Path with GeneCards custom track

Promoters for MIR940 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000502499 -55 2601 HDGF PKNOX1 ARNT CREB3L1 ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF2

Genomic Location for MIR940 Gene

Chromosome:
16
Start:
2,268,155 bp from pter
End:
2,273,418 bp from pter
Size:
5,264 bases
Orientation:
Plus strand

Genomic View for MIR940 Gene

Genes around MIR940 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR940 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR940 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR940 Gene

Proteins for MIR940 Gene

Post-translational modifications for MIR940 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR940 Gene

Domains & Families for MIR940 Gene

Gene Families for MIR940 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR940: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR940 Gene

Function for MIR940 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR940 Gene

Localization for MIR940 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR940 Gene

Pathways & Interactions for MIR940 Gene

SuperPathways for MIR940 Gene

No Data Available

Interacting Proteins for MIR940 Gene

Gene Ontology (GO) - Biological Process for MIR940 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR940 Gene

Transcripts for MIR940 Gene

mRNA/cDNA for MIR940 Gene

(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR940 Gene

No ASD Table

Relevant External Links for MIR940 Gene

GeneLoc Exon Structure for
MIR940
ECgene alternative splicing isoforms for
MIR940

Expression for MIR940 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR940 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR940 Gene:

MIR940
genes like me logo Genes that share expression patterns with MIR940: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR940 Gene

Orthologs for MIR940 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR940 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-940 35
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 35
  • 92 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-940 35
  • 91 (a)
OneToOne
Species where no ortholog for MIR940 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR940 Gene

ENSEMBL:
Gene Tree for MIR940 (if available)
TreeFam:
Gene Tree for MIR940 (if available)

Paralogs for MIR940 Gene

No data available for Paralogs for MIR940 Gene

Variants for MIR940 Gene

Sequence variations from dbSNP and Humsavar for MIR940 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs111289189 -- 2,270,872(+) CCCTT(A/G)CCTTC intron-variant, downstream-variant-500B, upstream-variant-2KB
rs112051780 -- 2,269,804(+) TGTCA(A/G)GTGTG intron-variant, upstream-variant-2KB
rs112497593 -- 2,270,885(+) AGAGC(G/T)GAGGG intron-variant, downstream-variant-500B, upstream-variant-2KB
rs112570120 -- 2,271,006(+) CCCTC(A/C)GAGGC intron-variant, downstream-variant-500B, upstream-variant-2KB
rs112802928 -- 2,271,156(+) CTGCA(C/G)TGAGG intron-variant, downstream-variant-500B, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR940 Gene

Variant ID Type Subtype PubMed ID
nsv952902 CNV deletion 24416366
nsv571201 CNV loss 21841781
nsv471072 CNV loss 18288195
nsv457353 CNV loss 19166990
nsv457351 CNV loss 19166990
nsv1052260 CNV gain 25217958
esv2422427 CNV duplication 17116639
dgv4863n54 CNV loss 21841781

Relevant External Links for MIR940 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR940

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR940 Gene

Disorders for MIR940 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR940 Gene - From: GeneCards

Disorder Aliases PubMed IDs
tetralogy of fallot
  • tetrology of fallot
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for MIR940

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR940
genes like me logo Genes that share disorders with MIR940: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR940 Gene

Publications for MIR940 Gene

  1. Salivary microRNAs show potential as a noninvasive biomarker for detecting resectable pancreatic cancer. (PMID: 25538087) Xie Z. … Li Z. (Cancer Prev Res (Phila) 2015) 3 64
  2. MiR-940 inhibited pancreatic ductal adenocarcinoma growth by targeting MyD88. (PMID: 25766528) Song B. … Liu C. (Cell. Physiol. Biochem. 2015) 3 64
  3. MiR-940 inhibits hepatocellular carcinoma growth and correlates with prognosis of hepatocellular carcinoma patients. (PMID: 25940592) Yuan B. … Luo F. (Cancer Sci. 2015) 3 64
  4. MicroRNA-940 promotes tumor cell invasion and metastasis by downregulating ZNF24 in gastric cancer. (PMID: 26317898) Liu X. … Li J. (Oncotarget 2015) 3 64
  5. miRNA-940 reduction contributes to human Tetralogy of Fallot development. (PMID: 24889693) Liang D. … Chen Y.H. (J. Cell. Mol. Med. 2014) 3 64

Products for MIR940 Gene

Sources for MIR940 Gene

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