Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR940 Gene

Subcategory (RNA class) for MIR940 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR940 Gene

  • MicroRNA 940 2 3 5
  • Hsa-Mir-940 3
  • Mir-940 3
  • MIRN940 3

External Ids for MIR940 Gene

Previous HGNC Symbols for MIR940 Gene

  • MIRN940

Previous GeneCards Identifiers for MIR940 Gene

  • GC16P002263
  • GC16P002321

Summaries for MIR940 Gene

Entrez Gene Summary for MIR940 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR940 Gene

MIR940 (MicroRNA 940) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR940 include Tetralogy Of Fallot.

Additional gene information for MIR940 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR940 Gene

Genomics for MIR940 Gene

GeneHancer (GH) Regulatory Elements for MIR940 Gene

Promoters and enhancers for MIR940 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16I002439 Enhancer 0.5 ENCODE 10.9 +168.7 168654 0.8 ZNF217 POLR2A ETV6 ELF1 NTN3 TBC1D24 ABCA3 ABCA17P RNPS1 ECI1 MIR940 PKD1 MIR6767 GC16P002435
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR940 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR940 Gene

Genomic Locations for MIR940 Gene
chr16:2,271,747-2,271,840
(GRCh38/hg38)
Size:
94 bases
Orientation:
Plus strand
chr16:2,318,156-2,323,419
(GRCh37/hg19)

Genomic View for MIR940 Gene

Genes around MIR940 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR940 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR940 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR940 Gene

Proteins for MIR940 Gene

Post-translational modifications for MIR940 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR940 Gene

Domains & Families for MIR940 Gene

Gene Families for MIR940 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR940: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR940 Gene

Function for MIR940 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR940 Gene

Localization for MIR940 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR940 Gene

Pathways & Interactions for MIR940 Gene

SuperPathways for MIR940 Gene

No Data Available

Interacting Proteins for MIR940 Gene

Gene Ontology (GO) - Biological Process for MIR940 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR940 Gene

Drugs & Compounds for MIR940 Gene

No Compound Related Data Available

Transcripts for MIR940 Gene

mRNA/cDNA for MIR940 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR940 Gene

No ASD Table

Relevant External Links for MIR940 Gene

GeneLoc Exon Structure for
MIR940
ECgene alternative splicing isoforms for
MIR940

Expression for MIR940 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR940 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR940 Gene:

MIR940
genes like me logo Genes that share expression patterns with MIR940: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR940 Gene

Orthologs for MIR940 Gene

Evolution for MIR940 Gene

ENSEMBL:
Gene Tree for MIR940 (if available)
TreeFam:
Gene Tree for MIR940 (if available)

No data available for Orthologs for MIR940 Gene

Paralogs for MIR940 Gene

No data available for Paralogs for MIR940 Gene

Variants for MIR940 Gene

Sequence variations from dbSNP and Humsavar for MIR940 Gene

SNP ID Clin Chr 16 pos Variation AA Info Type
rs1000205570 -- 2,270,509(+) T/C upstream_transcript_variant
rs1000593807 -- 2,271,557(+) C/T upstream_transcript_variant
rs1000657372 -- 2,270,200(+) A/G upstream_transcript_variant
rs1001401232 -- 2,271,497(+) A/C upstream_transcript_variant
rs1001601714 -- 2,271,017(+) G/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR940 Gene

Variant ID Type Subtype PubMed ID
dgv4863n54 CNV loss 21841781
esv2422427 CNV duplication 17116639
nsv1052260 CNV gain 25217958
nsv457351 CNV loss 19166990
nsv457353 CNV loss 19166990
nsv471072 CNV loss 18288195
nsv571201 CNV loss 21841781
nsv952902 CNV deletion 24416366

Additional Variant Information for MIR940 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR940

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR940 Gene

Disorders for MIR940 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR940 Gene - From: GeneCards

Disorder Aliases PubMed IDs
tetralogy of fallot
  • tof
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR940

genes like me logo Genes that share disorders with MIR940: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR940 Gene

Publications for MIR940 Gene

  1. Exosomal miR-940 maintains SRC-mediated oncogenic activity in cancer cells: a possible role for exosomal disposal of tumor suppressor miRNAs. (PMID: 28423620) Rashed MH … Berestein GL (Oncotarget 2017) 3 58
  2. miR-940 Upregulation Suppresses Cell Proliferation and Induces Apoptosis by Targeting PKC-δ in Ovarian Cancer OVCAR3 Cells. (PMID: 28081739) Wang F … Cui J (Oncology research 2017) 3 58
  3. miR-940 Suppresses Tumor Cell Invasion and Migration via Regulation of CXCR2 in Hepatocellular Carcinoma. (PMID: 27807540) Ding D … Li X (BioMed research international 2016) 3 58
  4. MiR-940 Inhibited Cell Growth and Migration in Triple-Negative Breast Cancer. (PMID: 27731867) Hou L … Jiang J (Medical science monitor : international medical journal of experimental and clinical research 2016) 3 58
  5. Over-expression of microRNA-940 promotes cell proliferation by targeting GSK3β and sFRP1 in human pancreatic carcinoma. (PMID: 27459115) Yang HW … Ye H (Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016) 3 58

Products for MIR940 Gene

Sources for MIR940 Gene

Content
Loading form....