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Aliases for MIR939 Gene

Subcategory (RNA class) for MIR939 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR939 Gene

  • MicroRNA 939 2 3 5
  • Hsa-Mir-939 3
  • Mir-939 3
  • MIRN939 3

External Ids for MIR939 Gene

Previous HGNC Symbols for MIR939 Gene

  • MIRN939

Previous GeneCards Identifiers for MIR939 Gene

  • GC08M145592
  • GC08M145621
  • GC08M145626
  • GC08M145627
  • GC08M140732
  • GC08M145630
  • GC08M145631
  • GC08M145632
  • GC08M145633

Summaries for MIR939 Gene

Entrez Gene Summary for MIR939 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR939 Gene

MIR939 (MicroRNA 939) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are mRNA Splicing - Major Pathway and Gene Expression.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR939 Gene

Genomics for MIR939 Gene

Regulatory Elements for MIR939 Gene

Enhancers for MIR939 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08G144396 0.7 ENCODE 0.7 -2.8 -2841 0.2 HDGF KLF1 AGO1 SP2 REST SP1 POLR2A KLF9 ZBTB33 IRF1 CPSF1 MIR939 MIR1234
GH08G144391 0.6 ENCODE 0.7 +2.6 2632 1.0 MAZ ZNF687 NFIB AGO1 MNT CTBP1 ZBTB33 MYC RBFOX2 VPS28 MIR939 ADCK5
GH08G144372 1.1 ENCODE 0.3 +20.3 20264 3.0 HDGF PKNOX1 CREB3L1 ARID4B SIN3A DMAP1 ZBTB7B YY1 CBX5 ZNF207 CPSF1 TONSL DGAT1 ADCK5 MIR939
GH08G144386 0.8 ENCODE 0.4 +7.1 7076 1.6 SOX13 PKNOX1 TFAP4 SAP130 FEZF1 ZBTB40 RARA HIC1 ZBTB48 HSF1 CPSF1 VPS28 TONSL-AS1 TONSL DGAT1 ENSG00000254690 HSF1 BOP1 SHARPIN WDR97
GH08G144375 0.4 ENCODE 0.4 +18.6 18626 0.1 BCOR SIN3A ADCK5 MIR939
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR939 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR939 Gene

Chromosome:
8
Start:
144,394,149 bp from pter
End:
144,394,230 bp from pter
Size:
82 bases
Orientation:
Minus strand

Genomic View for MIR939 Gene

Genes around MIR939 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR939 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR939 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR939 Gene

ORGUL Member Location for MIR939 Gene

ORGUL Member Location for MIR939 gene

Proteins for MIR939 Gene

Post-translational modifications for MIR939 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR939 Gene

Domains & Families for MIR939 Gene

Gene Families for MIR939 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR939: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR939 Gene

Function for MIR939 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR939 Gene

Localization for MIR939 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR939 Gene

Drugs & Compounds for MIR939 Gene

No Compound Related Data Available

Transcripts for MIR939 Gene

mRNA/cDNA for MIR939 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR939 Gene

No ASD Table

Relevant External Links for MIR939 Gene

GeneLoc Exon Structure for
MIR939
ECgene alternative splicing isoforms for
MIR939

Expression for MIR939 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR939 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR939 Gene:

MIR939
genes like me logo Genes that share expression patterns with MIR939: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR939 Gene

Orthologs for MIR939 Gene

Evolution for MIR939 Gene

ENSEMBL:
Gene Tree for MIR939 (if available)
TreeFam:
Gene Tree for MIR939 (if available)

No data available for Orthologs for MIR939 Gene

Paralogs for MIR939 Gene

No data available for Paralogs for MIR939 Gene

Variants for MIR939 Gene

Sequence variations from dbSNP and Humsavar for MIR939 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs1007267613 -- 144,396,178(+) CCTTT(A/G)GAGCA intron-variant, upstream-variant-2KB
rs1011447019 -- 144,395,923(+) AGGAA(A/G)CACTC intron-variant, upstream-variant-2KB
rs1016420747 -- 144,396,179(+) CTTTG(A/G)AGCAA intron-variant, upstream-variant-2KB
rs1018406221 -- 144,396,053(+) ACTCA(C/G)GTCAG intron-variant, upstream-variant-2KB
rs1019909665 -- 144,395,643(+) TTGCC(C/G)TCAGC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR939 Gene

Variant ID Type Subtype PubMed ID
dgv12434n54 CNV loss 21841781
dgv12437n54 CNV loss 21841781
esv2759652 CNV gain+loss 17122850
nsv428208 CNV gain 18775914
nsv470249 CNV loss 18288195
nsv515809 CNV gain+loss 19592680
nsv612934 CNV loss 21841781
nsv824805 CNV gain 20364138
nsv831489 CNV loss 17160897

Relevant External Links for MIR939 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR939

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR939 Gene

Disorders for MIR939 Gene

Relevant External Links for MIR939

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR939

No disorders were found for MIR939 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR939 Gene

Publications for MIR939 Gene

  1. Overexpression of hsa-miR-939 follows by NGFR down-regulation and apoptosis reduction. (PMID: 28229962) Aghdaei F.H. … Soleimani M. (J. Biosci. 2017) 3 64
  2. MicroRNA-939 down-regulates CD2-associated protein by targeting promoter in HEK-293T cells. (PMID: 26895305) Huang Y.P. … Zhou G.P. (Ren Fail 2016) 3 64
  3. MiR-939 promotes the proliferation of human ovarian cancer cells by repressing APC2 expression. (PMID: 25960217) Ying X. … Ji-hong L. (Biomed. Pharmacother. 2015) 3 64
  4. miRNA-939 regulates human inducible nitric oxide synthase posttranscriptional gene expression in human hepatocytes. (PMID: 22451906) Guo Z. … Geller D.A. (Proc. Natl. Acad. Sci. U.S.A. 2012) 3 64
  5. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64

Products for MIR939 Gene

Sources for MIR939 Gene

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