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Aliases for MIR92B Gene

Subcategory (RNA class) for MIR92B Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR92B Gene

  • MicroRNA 92b 2 3 5
  • Hsa-Mir-92b 3
  • Mir-92b 3
  • MIRN92B 3

External Ids for MIR92B Gene

ORGUL Members for MIR92B Gene

Previous HGNC Symbols for MIR92B Gene

  • MIRN92B

Previous GeneCards Identifiers for MIR92B Gene

  • GC01U902188
  • GC01P153433
  • GC01P155164

Summaries for MIR92B Gene

Entrez Gene Summary for MIR92B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR92B Gene

MIR92B (MicroRNA 92b) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR92B Gene

Genomics for MIR92B Gene

Regulatory Elements for MIR92B Gene

Enhancers for MIR92B Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01G155191 1.4 ENCODE dbSUPER 0.7 +0.0 26 6.5 CREB3L1 AGO1 ZFP64 SLC30A9 ZNF143 ZNF548 ZNF263 SP3 MEF2D ZNF610 GBAP1 KIAA0907 SYT11 ENSG00000271267 DPM3 ENSG00000231064 THBS3 MUC1 LOC105371450 MIR92B
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR92B on UCSC Golden Path with GeneCards custom track

Promoters for MIR92B Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000014041 -77 1001 PKNOX1 ATF1 CREB3L1 ZFP64 ARID4B SIN3A ZNF48 GLIS2 ZNF143 ZNF207
ENSR00000254615 -1377 801 HDGF CREB3L1 ARNT AGO1 ARID4B SIN3A ZNF2 ZNF766 ZNF207 ZNF143

Genomic Location for MIR92B Gene

Chromosome:
1
Start:
155,195,177 bp from pter
End:
155,195,272 bp from pter
Size:
96 bases
Orientation:
Plus strand

Genomic View for MIR92B Gene

Genes around MIR92B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR92B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR92B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR92B Gene

Proteins for MIR92B Gene

Post-translational modifications for MIR92B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR92B Gene

Domains & Families for MIR92B Gene

Gene Families for MIR92B Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR92B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR92B Gene

Function for MIR92B Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR92B Gene

Localization for MIR92B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR92B Gene

Pathways & Interactions for MIR92B Gene

SuperPathways for MIR92B Gene

No Data Available

Interacting Proteins for MIR92B Gene

Gene Ontology (GO) - Biological Process for MIR92B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR92B Gene

Drugs & Compounds for MIR92B Gene

No Compound Related Data Available

Transcripts for MIR92B Gene

mRNA/cDNA for MIR92B Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR92B Gene

No ASD Table

Relevant External Links for MIR92B Gene

GeneLoc Exon Structure for
MIR92B
ECgene alternative splicing isoforms for
MIR92B

Expression for MIR92B Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR92B Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR92B Gene:

MIR92B
genes like me logo Genes that share expression patterns with MIR92B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR92B Gene

Orthologs for MIR92B Gene

Evolution for MIR92B Gene

ENSEMBL:
Gene Tree for MIR92B (if available)
TreeFam:
Gene Tree for MIR92B (if available)

No data available for Orthologs for MIR92B Gene

Paralogs for MIR92B Gene

No data available for Paralogs for MIR92B Gene

Variants for MIR92B Gene

Sequence variations from dbSNP and Humsavar for MIR92B Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000779176 -- 155,195,516(+) TTTCT(A/C)TTCTA downstream-variant-500B, upstream-variant-2KB
rs1001146257 -- 155,195,125(+) CCAGC(A/G)CGCCC downstream-variant-500B, upstream-variant-2KB
rs1004177114 -- 155,193,255(+) GTCGA(C/G)GTCCT upstream-variant-2KB
rs1005182379 -- 155,194,767(+) GCGGG(A/G)TGGGG upstream-variant-2KB
rs1005297232 -- 155,194,460(+) CCAAG(A/G)GGTGT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR92B Gene

Variant ID Type Subtype PubMed ID
dgv3n68 CNV loss 17160897
esv2758971 CNV gain 17122850
nsv1010146 CNV gain 25217958
nsv2988 CNV insertion 18451855
nsv464084 CNV loss 19166990
nsv470741 CNV loss 18288195
nsv527682 CNV gain 19592680
nsv547961 CNV loss 21841781

Relevant External Links for MIR92B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR92B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR92B Gene

Disorders for MIR92B Gene

Relevant External Links for MIR92B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR92B

No disorders were found for MIR92B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR92B Gene

Publications for MIR92B Gene

  1. MicroRNA-92a Promotes Cell Proliferation in Cervical Cancer via Inhibiting p21 Expression and Promoting Cell Cycle Progression. (PMID: 28081742) Su Z. … Chen R. (Oncol. Res. 2017) 3 64
  2. miR-92b regulates glioma cells proliferation, migration, invasion, and apoptosis via PTEN/Akt signaling pathway. (PMID: 26893028) Song H. … Yuan L. (J. Physiol. Biochem. 2016) 3 64
  3. Promotion of tumour proliferation, migration and invasion by miR-92b in targeting RECK in osteosarcoma. (PMID: 26993249) Zhou Z. … Xiao J. (Clin. Sci. 2016) 3 64
  4. MicroRNA-92b promotes hepatocellular carcinoma progression by targeting Smad7 and is mediated by long non-coding RNA XIST. (PMID: 27100897) Zhuang L.K. … Qu Z.Q. (Cell Death Dis 2016) 3 64
  5. miR-92b targets DAB2IP to promote EMT in bladder cancer migration and invasion. (PMID: 27430302) Huang J. … Wu K. (Oncol. Rep. 2016) 3 64

Products for MIR92B Gene

Sources for MIR92B Gene

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