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Aliases for MIR92A2 Gene

Subcategory (RNA class) for MIR92A2 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR92A2 Gene

  • MicroRNA 92a-2 2 3
  • MicroRNA 92-2 2 3
  • MicroRNA 19b-2 5
  • Hsa-Mir-92a-2 3
  • Hsa-Mir-92-2 3
  • MIRN92A-2 3
  • Mir-92a-2 3
  • MIRN92-2 3
  • MIRN92A2 3
  • MIR19B2 5

External Ids for MIR92A2 Gene

Previous HGNC Symbols for MIR92A2 Gene

  • MIRN92-2
  • MIRN92A2

Previous GeneCards Identifiers for MIR92A2 Gene

  • GC0XM133151
  • GC0XM133158
  • GC0XM133305
  • GC0XM133310
  • GC0XM133314
  • GC0XM133318
  • GC0XM133323
  • GC0XM133327
  • GC0XM133331
  • GC0XM133335
  • GC0XM133347
  • GC0XM133372
  • GC0XM134171
  • GC0XM134176

Summaries for MIR92A2 Gene

Entrez Gene Summary for MIR92A2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR92A2 Gene

MIR92A2 (MicroRNA 92a-2) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Parkinsons Disease Pathway and MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR92A2 Gene

Genomics for MIR92A2 Gene

Regulatory Elements for MIR92A2 Gene

Enhancers for MIR92A2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH0XF134171 1.3 FANTOM5 Ensembl ENCODE 0.8 +0.5 455 4.8 MAX ZNF76 ZIC2 ZNF664 ZFHX2 GLIS2 POLR2A PATZ1 ZNF143 PRDM10 CCDC160 GPC3 PHF6 GC0XM134196 GC0XM134201 MIR92A2 MIR106A MIR18B MIR19B2 MIR20B
GH0XF134179 0.2 ENCODE 0.4 -6.9 -6879 2.4 ZNF133 MIR106A MIR18B MIR19B2 MIR20B MIR363 MIR92A2 LARP1BP3
GH0XF134187 0.2 Ensembl 0.4 -13.2 -13212 0.2 CBX8 CCDC160 MIR106A MIR18B MIR19B2 MIR20B MIR363 MIR92A2 LARP1BP3
GH0XF134186 0.4 ENCODE 0.4 -12.9 -12857 0.2 CBX8 CCDC160 MIR106A MIR18B MIR19B2 MIR20B MIR363 MIR92A2 LARP1BP3
GH0XF134188 0.2 Ensembl 0.4 -12.4 -12412 0.2 CCDC160 MIR106A MIR18B MIR19B2 MIR20B MIR363 MIR92A2 LARP1BP3
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR92A2 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR92A2 Gene

Chromosome:
X
Start:
134,168,911 bp from pter
End:
134,174,089 bp from pter
Size:
5,179 bases
Orientation:
Minus strand

Genomic View for MIR92A2 Gene

Genes around MIR92A2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR92A2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR92A2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR92A2 Gene

Proteins for MIR92A2 Gene

Post-translational modifications for MIR92A2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR92A2 Gene

Domains & Families for MIR92A2 Gene

Gene Families for MIR92A2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR92A2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR92A2 Gene

Function for MIR92A2 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR92A2 Gene

Localization for MIR92A2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR92A2 Gene

Pathways & Interactions for MIR92A2 Gene

genes like me logo Genes that share pathways with MIR92A2: view

Pathways by source for MIR92A2 Gene

1 BioSystems pathway for MIR92A2 Gene
1 KEGG pathway for MIR92A2 Gene

Interacting Proteins for MIR92A2 Gene

Gene Ontology (GO) - Biological Process for MIR92A2 Gene

None

No data available for SIGNOR curated interactions for MIR92A2 Gene

Transcripts for MIR92A2 Gene

mRNA/cDNA for MIR92A2 Gene

(7) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR92A2 Gene

No ASD Table

Relevant External Links for MIR92A2 Gene

GeneLoc Exon Structure for
MIR92A2
ECgene alternative splicing isoforms for
MIR92A2

Expression for MIR92A2 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR92A2 Gene:

MIR92A2
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR92A2 Gene

Orthologs for MIR92A2 Gene

Evolution for MIR92A2 Gene

ENSEMBL:
Gene Tree for MIR92A2 (if available)
TreeFam:
Gene Tree for MIR92A2 (if available)

No data available for Orthologs for MIR92A2 Gene

Paralogs for MIR92A2 Gene

No data available for Paralogs for MIR92A2 Gene

Variants for MIR92A2 Gene

Sequence variations from dbSNP and Humsavar for MIR92A2 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs113658998 -- 134,170,166(+) CACAA(A/G)CTACA downstream-variant-500B, upstream-variant-2KB
rs137881717 -- 134,171,170(+) TAAAC(A/G)AGTGA upstream-variant-2KB
rs142112727 -- 134,171,521(+) TCTGG(C/T)ATCCC upstream-variant-2KB
rs142600536 -- 134,169,291(+) ATTAT(C/T)TTTTA downstream-variant-500B
rs142900355 -- 134,169,185(+) TGAGG(C/T)TCATT downstream-variant-500B

Relevant External Links for MIR92A2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR92A2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR92A2 Gene

Disorders for MIR92A2 Gene

Relevant External Links for MIR92A2

Genetic Association Database (GAD)
MIR92A2
Human Genome Epidemiology (HuGE) Navigator
MIR92A2
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR92A2

No disorders were found for MIR92A2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR92A2 Gene

Publications for MIR92A2 Gene

  1. MicroRNAs and target site screening reveals a pre-microRNA-30e variant associated with schizophrenia. (PMID: 20347265) Xu Y. … Liu P. (Schizophr. Res. 2010) 3 46 64
  2. miR-92a is upregulated in cervical cancer and promotes cell proliferation and invasion by targeting FBXW7. (PMID: 25623537) Zhou C. … Yu H. (Biochem. Biophys. Res. Commun. 2015) 3 64
  3. High concentrations of uric acid inhibit angiogenesis via regulation of the KrA1ppel-like factor 2-vascular endothelial growth factor-A axis by miR-92a. (PMID: 26299712) Yu S. … Wu D. (Circ. J. 2015) 3 64
  4. Overexpression of miR-92a correlates with tumor metastasis and poor prognosis in patients with colorectal cancer. (PMID: 22772712) Zhou T. … Tian H. (Int J Colorectal Dis 2013) 3 64
  5. Downregulation of miR-92a is associated with aggressive breast cancer features and increased tumour macrophage infiltration. (PMID: 22563438) Nilsson S. … Landberg G. (PLoS ONE 2012) 3 64

Products for MIR92A2 Gene

Sources for MIR92A2 Gene

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