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Aliases for MIR92A2 Gene

Subcategory (RNA class) for MIR92A2 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR92A2 Gene

  • MicroRNA 92a-2 2 3
  • MicroRNA 92-2 2 3
  • Hsa-Mir-92a-2 3
  • Hsa-Mir-92-2 3
  • MIRN92A-2 3
  • MIRN92-2 3
  • MIRN92A2 3

External Ids for MIR92A2 Gene

Previous HGNC Symbols for MIR92A2 Gene

  • MIRN92-2
  • MIRN92A2

Previous GeneCards Identifiers for MIR92A2 Gene

  • GC0XM133151
  • GC0XM133158
  • GC0XM133305
  • GC0XM133310
  • GC0XM133314
  • GC0XM133318
  • GC0XM133323
  • GC0XM133327
  • GC0XM133331
  • GC0XM133335
  • GC0XM133347
  • GC0XM133372

Summaries for MIR92A2 Gene

Entrez Gene Summary for MIR92A2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR92A2 Gene

MIR92A2 (MicroRNA 92a-2) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR92A2 Gene

Genomics for MIR92A2 Gene

Genomic Location for MIR92A2 Gene

Start:
134,169,538 bp from pter
End:
134,169,612 bp from pter
Size:
75 bases
Orientation:
Minus strand

Genomic View for MIR92A2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR92A2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR92A2 Gene

No data available for Regulatory Elements for MIR92A2 Gene

Proteins for MIR92A2 Gene

Post-translational modifications for MIR92A2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR92A2 Gene

Domains for MIR92A2 Gene

Gene Families for MIR92A2 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR92A2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR92A2 Gene

Function for MIR92A2 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR92A2 Gene

Localization for MIR92A2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR92A2 Gene

Pathways for MIR92A2 Gene

SuperPathways for MIR92A2 Gene

Superpath Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR92A2: view

Pathways by source for MIR92A2 Gene

1 KEGG pathway for MIR92A2 Gene

Interacting Proteins for MIR92A2 Gene

Gene Ontology (GO) - Biological Process for MIR92A2 Gene

None

Transcripts for MIR92A2 Gene

mRNA/cDNA for MIR92A2 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR92A2 Gene

No ASD Table

Relevant External Links for MIR92A2 Gene

GeneLoc Exon Structure for
MIR92A2
ECgene alternative splicing isoforms for
MIR92A2

Expression for MIR92A2 Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR92A2 Gene

Orthologs for MIR92A2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR92A2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-92-2 36
  • 82 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-92a-2 36
  • 82 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-92a-2 36
  • 97 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir92-2 36
  • 74 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-92a-2 36
  • 51 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-92a-1 36
  • 52 (a)
OneToOne
chicken
(Gallus gallus)
Aves -- 36
  • 54 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-92a-2 36
  • 75 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dre-mir-92a-1 36
  • 64 (a)
OneToMany
dre-mir-92a-2 36
  • 47 (a)
OneToMany
Species with no ortholog for MIR92A2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR92A2 Gene

ENSEMBL:
Gene Tree for MIR92A2 (if available)
TreeFam:
Gene Tree for MIR92A2 (if available)

Paralogs for MIR92A2 Gene

No data available for Paralogs for MIR92A2 Gene

Variants for MIR92A2 Gene

Relevant External Links for MIR92A2 Gene

HapMap Linkage Disequilibrium report
MIR92A2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for MIR92A2 Gene

Disorders for MIR92A2 Gene

Relevant External Links for MIR92A2

Genetic Association Database (GAD)
MIR92A2
Human Genome Epidemiology (HuGE) Navigator
MIR92A2
genes like me logo Genes that share disorders with MIR92A2: view

No data available for UniProtKB/Swiss-Prot for MIR92A2 Gene

Publications for MIR92A2 Gene

  1. MicroRNAs and target site screening reveals a pre-microRNA-30e variant associated with schizophrenia. (PMID: 20347265) Xu Y. … Liu P. (Schizophr. Res. 2010) 3 48
  2. MicroRNA 92a-2*: a biomarker predictive for chemoresistance and prognostic for survival in patients with small cell lung cancer. (PMID: 20548249) Ranade A.R. … Weiss G.J. (J Thorac Oncol 2010) 3
  3. Downregulation of miR-92a is associated with aggressive breast cancer features and increased tumour macrophage infiltration. (PMID: 22563438) Nilsson S. … Landberg G. (PLoS ONE 2012) 3
  4. Overexpression of miR-92a correlates with tumor metastasis and poor prognosis in patients with colorectal cancer. (PMID: 22772712) Zhou T. … Tian H. (Int J Colorectal Dis 2013) 3
  5. Inhibition of miR-92a increases endothelial proliferation and migration in vitro as well as reduces neointimal proliferation in vivo after vascular injury. (PMID: 22890560) Iaconetti C. … Indolfi C. (Basic Res. Cardiol. 2012) 3

Products for MIR92A2 Gene

Sources for MIR92A2 Gene

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