Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR922 Gene

Subcategory (RNA class) for MIR922 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR922 Gene

  • MicroRNA 922 2 3 5
  • Hsa-Mir-922 3
  • MIRN922 3

External Ids for MIR922 Gene

Previous HGNC Symbols for MIR922 Gene

  • MIRN922

Previous GeneCards Identifiers for MIR922 Gene

  • GC03M198888
  • GC03M197401

Summaries for MIR922 Gene

Entrez Gene Summary for MIR922 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR922 Gene

MIR922 (MicroRNA 922) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR922 include Spinocerebellar Ataxia, Autosomal Recessive 15.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR922 Gene

Genomics for MIR922 Gene

Regulatory Elements for MIR922 Gene

Enhancers for MIR922 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH03G197515 1.9 FANTOM5 Ensembl ENCODE dbSUPER 9.5 +154.9 154928 7.5 HDGF PKNOX1 FOXA2 ARID4B SIN3A DMAP1 ZNF48 YY1 SLC30A9 CBX5 MIR922 BDH1 GC03P197515
GH03G197729 1.5 Ensembl ENCODE dbSUPER 10.2 -55.7 -55720 1.5 ATF1 CREB3L1 ZFP64 ARID4B SIN3A DMAP1 ZNF48 YY1 ELK1 MXD4 MIR922 LOC220729 FYTTD1 PIR54031
GH03G197572 1 ENCODE 10.2 +100.3 100336 3.4 FOXA2 PKNOX1 ATF1 MLX ARID4B DMAP1 ZNF48 YY1 SLC30A9 ZNF766 BDH1 MIR922 RPL36P7
GH03G197592 0.9 ENCODE 10.7 +81.7 81748 1.1 HDAC1 ATF1 CBX3 NFRKB ZBTB40 TCF12 CBX5 ETV6 SMARCA5 ZBTB2 MIR922 PIR46687 RPL36P7
GH03G197701 0.8 ENCODE 11.7 -27.5 -27456 1.6 ZNF2 ZNF335 ZNF366 SCRT2 KLF7 KLF13 DEK SP3 ZNF341 NBN LOC220729 MIR922 SENP5 FYTTD1 RUBCN LMLN MELTF-AS1 PIR54031
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR922 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR922 Gene

Chromosome:
3
Start:
197,674,496 bp from pter
End:
197,674,576 bp from pter
Size:
81 bases
Orientation:
Minus strand

Genomic View for MIR922 Gene

Genes around MIR922 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR922 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR922 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR922 Gene

ORGUL Member Location for MIR922 Gene

ORGUL Member Location for MIR922 gene

Proteins for MIR922 Gene

Post-translational modifications for MIR922 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR922 Gene

Domains & Families for MIR922 Gene

Gene Families for MIR922 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR922: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR922 Gene

Function for MIR922 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR922 Gene

Localization for MIR922 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR922 Gene

Pathways & Interactions for MIR922 Gene

SuperPathways for MIR922 Gene

No Data Available

Interacting Proteins for MIR922 Gene

Gene Ontology (GO) - Biological Process for MIR922 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR922 Gene

Drugs & Compounds for MIR922 Gene

No Compound Related Data Available

Transcripts for MIR922 Gene

mRNA/cDNA for MIR922 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR922 Gene

No ASD Table

Relevant External Links for MIR922 Gene

GeneLoc Exon Structure for
MIR922
ECgene alternative splicing isoforms for
MIR922

Expression for MIR922 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR922 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR922 Gene:

MIR922
genes like me logo Genes that share expression patterns with MIR922: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR922 Gene

Orthologs for MIR922 Gene

Evolution for MIR922 Gene

ENSEMBL:
Gene Tree for MIR922 (if available)
TreeFam:
Gene Tree for MIR922 (if available)

No data available for Orthologs for MIR922 Gene

Paralogs for MIR922 Gene

No data available for Paralogs for MIR922 Gene

Variants for MIR922 Gene

Sequence variations from dbSNP and Humsavar for MIR922 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs28562770 Likely benign 197,675,081(+) TAGTC(C/T)GACAG upstream-variant-2KB, reference, synonymous-codon
rs1000722337 -- 197,675,486(+) CAGAA(C/T)TCACA upstream-variant-2KB, reference, synonymous-codon
rs1001519712 -- 197,676,055(+) CTGCA(C/T)TTTCA intron-variant, upstream-variant-2KB
rs1001892842 -- 197,675,447(+) TGGAG(C/T)TCAAA upstream-variant-2KB, reference, synonymous-codon
rs1001913678 -- 197,675,257(+) TAGAG(A/G)TCAGT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR922 Gene

Variant ID Type Subtype PubMed ID
dgv5042n100 CNV gain 25217958
esv2759214 CNV gain+loss 17122850
esv3575646 CNV gain 25503493
esv3599313 CNV gain 21293372
esv3599318 CNV gain 21293372
esv3599319 CNV gain 21293372
nsv1011831 CNV gain 25217958
nsv428433 CNV gain+loss 18775914
nsv508983 CNV insertion 20534489
nsv829831 CNV loss 17160897

Relevant External Links for MIR922 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR922

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR922 Gene

Disorders for MIR922 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR922 Gene - From: GeneCards

Disorder Aliases PubMed IDs
spinocerebellar ataxia, autosomal recessive 15
  • autosomal recessive spinocerebellar ataxia 15
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for MIR922

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR922
genes like me logo Genes that share disorders with MIR922: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR922 Gene

Publications for MIR922 Gene

  1. miR-922 regulates CYLD expression and promotes the cell proliferation of human hepatocellular carcinoma. (PMID: 28184924) Liu J. … Liu G. (Oncol. Rep. 2017) 3 64
  2. MicroRNA-922 promotes tau phosphorylation by downregulating ubiquitin carboxy-terminal hydrolase L1 (UCHL1) expression in the pathogenesis of Alzheimer's disease. (PMID: 24950120) Zhao Z.B. … Chen S.D. (Neuroscience 2014) 3 64
  3. Regulated microRNAs in the CSF of patients with multiple sclerosis: a case-control study. (PMID: 23077021) Haghikia A. … Gold R. (Neurology 2012) 3 64
  4. Analysis of gene expression in normal and neoplastic human testis: new roles of RNA. (PMID: 17573847) Novotny G.W. … Leffers H. (Int. J. Androl. 2007) 3 64
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR922 Gene

Sources for MIR922 Gene

Content
Loading form....