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Aliases for MIR9-3 Gene

Subcategory (RNA class) for MIR9-3 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR9-3 Gene

  • MicroRNA 9-3 2 3 5
  • Hsa-Mir-9-3 3
  • MiRNA9-3 3
  • Mir-9-3 3
  • MIRN9-3 3

External Ids for MIR9-3 Gene

ORGUL Members for MIR9-3 Gene

Previous HGNC Symbols for MIR9-3 Gene

  • MIRN9-3

Previous GeneCards Identifiers for MIR9-3 Gene

  • GC15P087715
  • GC15P089911

Summaries for MIR9-3 Gene

Entrez Gene Summary for MIR9-3 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR9-3 Gene

MIR9-3 (MicroRNA 9-3) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR9-3 Gene

Genomics for MIR9-3 Gene

Regulatory Elements for MIR9-3 Gene

Enhancers for MIR9-3 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MIR9-3 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR9-3 Gene

Chromosome:
15
Start:
89,368,017 bp from pter
End:
89,368,106 bp from pter
Size:
90 bases
Orientation:
Plus strand

Genomic View for MIR9-3 Gene

Genes around MIR9-3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR9-3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR9-3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR9-3 Gene

Proteins for MIR9-3 Gene

Post-translational modifications for MIR9-3 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR9-3 Gene

Domains & Families for MIR9-3 Gene

Gene Families for MIR9-3 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR9-3: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR9-3 Gene

Function for MIR9-3 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR9-3 Gene

Localization for MIR9-3 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR9-3 Gene

Pathways & Interactions for MIR9-3 Gene

SuperPathways for MIR9-3 Gene

Superpath Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR9-3: view

Pathways by source for MIR9-3 Gene

1 KEGG pathway for MIR9-3 Gene

Interacting Proteins for MIR9-3 Gene

Gene Ontology (GO) - Biological Process for MIR9-3 Gene

None

No data available for SIGNOR curated interactions for MIR9-3 Gene

Drugs & Compounds for MIR9-3 Gene

No Compound Related Data Available

Transcripts for MIR9-3 Gene

mRNA/cDNA for MIR9-3 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR9-3 Gene

No ASD Table

Relevant External Links for MIR9-3 Gene

GeneLoc Exon Structure for
MIR9-3
ECgene alternative splicing isoforms for
MIR9-3

Expression for MIR9-3 Gene

mRNA expression in normal human tissues for MIR9-3 Gene

genes like me logo Genes that share expression patterns with MIR9-3: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR9-3 Gene

Orthologs for MIR9-3 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR9-3 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia bta-mir-9-1 36
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-9-3 36
  • 99 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-9a-1 36
  • 90 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir9-3 36
  • 99 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-9-1 36
  • 51 (a)
ManyToMany
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 99 (a)
OneToOne
chicken
(Gallus gallus)
Aves -- 36
  • 86 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-9-1 36
  • 55 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii dre-mir-9-3 36
  • 74 (a)
OneToMany
dre-mir-9-6 36
  • 77 (a)
OneToMany
dre-mir-9-7 36
  • 77 (a)
OneToMany
Species with no ortholog for MIR9-3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR9-3 Gene

ENSEMBL:
Gene Tree for MIR9-3 (if available)
TreeFam:
Gene Tree for MIR9-3 (if available)

Paralogs for MIR9-3 Gene

No data available for Paralogs for MIR9-3 Gene

Variants for MIR9-3 Gene

Sequence variations from dbSNP and Humsavar for MIR9-3 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs59818966 -- 89,367,376(+) AGCAT(G/T)CTTGT upstream-variant-2KB
rs79570836 -- 89,366,693(+) GGGCT(C/T)AAGGC upstream-variant-2KB
rs141026254 -- 89,367,046(+) TCTAG(C/G)AACCG upstream-variant-2KB
rs150122244 -- 89,366,689(+) CATAG(G/T)GCTCA upstream-variant-2KB
rs74439325 -- 89,367,073(+) TAGCA(A/G)CTTGG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR9-3 Gene

Variant ID Type Subtype PubMed ID
nsv833086 CNV Loss 17160897
dgv2433n71 CNV Loss 21882294

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Variation tolerance and Relevant External Links for MIR9-3 Gene

Disorders for MIR9-3 Gene

Relevant External Links for MIR9-3

Genetic Association Database (GAD)
MIR9-3
Human Genome Epidemiology (HuGE) Navigator
MIR9-3
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR9-3

No disorders were found for MIR9-3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR9-3 Gene

Publications for MIR9-3 Gene

  1. Novel genetic variants in miR-191 gene and familial ovarian cancer. (PMID: 20167074) Shen J. … Zhao H. (BMC Cancer 2010) 3 48 67
  2. miR-9 enhances the transactivation of nuclear factor of activated T cells by targeting KPNB1 and DYRK1B. (PMID: 25696812) Zeng Y. … Gou D. (Am. J. Physiol., Cell Physiol. 2015) 3
  3. Infrequent DNA methylation of miR-9-1 and miR-9-3 in multiple myeloma. (PMID: 25855800) Zhang Q. … Chim C.S. (J. Clin. Pathol. 2015) 3
  4. Regulation of UHRF1 by microRNA-9 modulates colorectal cancer cell proliferation and apoptosis. (PMID: 25940709) Zhu M. … Yan F. (Cancer Sci. 2015) 3
  5. miR-9-3p plays a tumour-suppressor role by targeting TAZ (WWTR1) in hepatocellular carcinoma cells. (PMID: 26125451) Higashi T. … Baba H. (Br. J. Cancer 2015) 3

Products for MIR9-3 Gene

Sources for MIR9-3 Gene

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