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Aliases for MIR9-3 Gene

Subcategory (RNA class) for MIR9-3 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR9-3 Gene

  • MicroRNA 9-3 2 3
  • MIR9-3 Host Gene 5
  • Hsa-Mir-9-3 3
  • MiRNA9-3 3
  • MIR9-3HG 5
  • Mir-9-3 3
  • MIRN9-3 3

External Ids for MIR9-3 Gene

Previous HGNC Symbols for MIR9-3 Gene

  • MIRN9-3

Previous GeneCards Identifiers for MIR9-3 Gene

  • GC15P087715
  • GC15P089911
  • GC15P089368

Summaries for MIR9-3 Gene

Entrez Gene Summary for MIR9-3 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR9-3 Gene

MIR9-3 (MicroRNA 9-3) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer and Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins..

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR9-3 Gene

Genomics for MIR9-3 Gene

Regulatory Elements for MIR9-3 Gene

Enhancers for MIR9-3 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH15F089411 0.4 ENCODE 12.7 +50.1 50066 0.2 SIN3A RAD21 ELK1 ZNF143 CREM HCFC1 USF2 MIER2 REST ZNF592 MIR9-3 MIR9-3HG POLG LOC105371031 GC15M089390
GH15F089416 0.5 ENCODE 12.3 +54.9 54906 0.2 CBX3 ZBTB40 ZNF2 RAD21 ZNF366 ZNF143 CREM ZNF263 ZNF362 MIER1 MIR9-3 MIR9-3HG GC15M089390 LOC105371031
GH15F089412 1.1 ENCODE 12.3 +51.7 51690 0.8 JUND ZNF366 ZZZ3 ENSG00000173867 RPL36AP43 MIR9-3 MIR9-3HG DET1 ARPIN GC15M089390 LOC105371031
GH15F089441 1 Ensembl ENCODE 11.7 +80.2 80199 1.2 HDGF KLF1 ESRRA ZIC2 ZBTB40 ZKSCAN1 HIC1 GATA3 CTBP1 GLIS2 MIR9-3 MIR9-3HG GC15M089390 GC15P089452
GH15F089442 0.6 ENCODE 11.7 +81.3 81326 0.2 CTCF SMC3 TRIM22 ZBTB8A REST ZNF48 RAD21 MIR9-3 MIR9-3HG GC15P089452 GC15M089390
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR9-3 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR9-3 Gene

Chromosome:
15
Start:
89,361,579 bp from pter
End:
89,398,487 bp from pter
Size:
36,909 bases
Orientation:
Plus strand

Genomic View for MIR9-3 Gene

Genes around MIR9-3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR9-3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR9-3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR9-3 Gene

Proteins for MIR9-3 Gene

Post-translational modifications for MIR9-3 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR9-3 Gene

Domains & Families for MIR9-3 Gene

Gene Families for MIR9-3 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR9-3: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR9-3 Gene

Function for MIR9-3 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR9-3 Gene

Localization for MIR9-3 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR9-3 Gene

Pathways & Interactions for MIR9-3 Gene

genes like me logo Genes that share pathways with MIR9-3: view

Pathways by source for MIR9-3 Gene

1 BioSystems pathway for MIR9-3 Gene
1 KEGG pathway for MIR9-3 Gene

Interacting Proteins for MIR9-3 Gene

Gene Ontology (GO) - Biological Process for MIR9-3 Gene

None

No data available for SIGNOR curated interactions for MIR9-3 Gene

Transcripts for MIR9-3 Gene

mRNA/cDNA for MIR9-3 Gene

(13) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR9-3 Gene

No ASD Table

Relevant External Links for MIR9-3 Gene

GeneLoc Exon Structure for
MIR9-3
ECgene alternative splicing isoforms for
MIR9-3

Expression for MIR9-3 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR9-3 Gene

genes like me logo Genes that share expression patterns with MIR9-3: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR9-3 Gene

Orthologs for MIR9-3 Gene

Evolution for MIR9-3 Gene

ENSEMBL:
Gene Tree for MIR9-3 (if available)
TreeFam:
Gene Tree for MIR9-3 (if available)

No data available for Orthologs for MIR9-3 Gene

Paralogs for MIR9-3 Gene

No data available for Paralogs for MIR9-3 Gene

Variants for MIR9-3 Gene

Sequence variations from dbSNP and Humsavar for MIR9-3 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs113050806 -- 89,366,970(+) ATTTA(A/G)CCAGG intron-variant, upstream-variant-2KB
rs113563465 -- 89,366,230(+) CCACA(A/G)ACAAG intron-variant, upstream-variant-2KB
rs115363896 -- 89,367,042(+) TGTGT(A/C)TAGGA intron-variant, upstream-variant-2KB
rs117451939 -- 89,366,717(+) CAGCA(A/G)CAAGG intron-variant, upstream-variant-2KB
rs118085761 -- 89,366,072(+) TCCAG(A/C)CCTTG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR9-3 Gene

Variant ID Type Subtype PubMed ID
nsv1038140 CNV gain 25217958
nsv833086 CNV loss 17160897

Relevant External Links for MIR9-3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR9-3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR9-3 Gene

Disorders for MIR9-3 Gene

Relevant External Links for MIR9-3

Genetic Association Database (GAD)
MIR9-3
Human Genome Epidemiology (HuGE) Navigator
MIR9-3
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR9-3

No disorders were found for MIR9-3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR9-3 Gene

Publications for MIR9-3 Gene

  1. Novel genetic variants in miR-191 gene and familial ovarian cancer. (PMID: 20167074) Shen J. … Zhao H. (BMC Cancer 2010) 3 46 64
  2. Down-regulation of microRNA-9 leads to activation of IL-6/Jak/STAT3 pathway through directly targeting IL-6 in HeLa cell. (PMID: 25809226) Zhang J. … Lu F. (Mol. Carcinog. 2016) 3 64
  3. Association of Decreased Expression of Serum miR-9 with Poor Prognosis of Oral Squamous Cell Carcinoma Patients. (PMID: 26813876) Sun L. … Shi Y. (Med. Sci. Monit. 2016) 3 64
  4. MicroRNA-9 inhibits hyperglycemia-induced pyroptosis in human ventricular cardiomyocytes by targeting ELAVL1. (PMID: 26898797) Jeyabal P. … Krishnamurthy P. (Biochem. Biophys. Res. Commun. 2016) 3 64
  5. miR-9 enhances the transactivation of nuclear factor of activated T cells by targeting KPNB1 and DYRK1B. (PMID: 25696812) Zeng Y. … Gou D. (Am. J. Physiol., Cell Physiol. 2015) 3 64

Products for MIR9-3 Gene

Sources for MIR9-3 Gene

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