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Aliases for MIR9-3 Gene

Subcategory (RNA class) for MIR9-3 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR9-3 Gene

  • MicroRNA 9-3 2 3
  • MIRN9-3 3 6
  • Hsa-Mir-9-3 3
  • MiRNA9-3 3

External Ids for MIR9-3 Gene

ORGUL Members for MIR9-3 Gene

Previous Symbols for MIR9-3 Gene

  • MIRN9-3

Summaries for MIR9-3 Gene

Entrez Gene Summary for MIR9-3 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR9-3 Gene

MIR9-3 (MicroRNA 9-3) is a RNA Gene, and belongs to miRNA RNA class. Diseases associated with MIR9-3 include clear cell renal cell carcinoma and renal cell carcinoma. Among its related pathways are MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR9-3 Gene

Genomics for MIR9-3 Gene

Genomic Location for MIR9-3 Gene

Start:
89,368,017 bp from pter
End:
89,368,106 bp from pter
Size:
90 bases
Orientation:
Plus strand

Genomic View for MIR9-3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR9-3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR9-3 Gene

No data available for Regulatory Elements for MIR9-3 Gene

Proteins for MIR9-3 Gene

Post-translational modifications for MIR9-3 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR9-3 Gene

Domains for MIR9-3 Gene

Gene Families for MIR9-3 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs
genes like me logo Genes that share domains with MIR9-3: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for MIR9-3 Gene

Function for MIR9-3 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR9-3 Gene

Localization for MIR9-3 Gene

No data available for Gene Ontology (GO) - Cellular Components for MIR9-3 Gene

Pathways for MIR9-3 Gene

SuperPathways for MIR9-3 Gene

Superpath Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR9-3: view

Pathways by source for MIR9-3 Gene

1 KEGG pathway for MIR9-3 Gene

Interacting Proteins for MIR9-3 Gene

Gene Ontology (GO) - Biological Process for MIR9-3 Gene

None

Transcripts for MIR9-3 Gene

mRNA/cDNA for MIR9-3 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR9-3 Gene

No ASD Table

Relevant External Links for MIR9-3 Gene

GeneLoc Exon Structure for
MIR9-3
ECgene alternative splicing isoforms for
MIR9-3

Expression for MIR9-3 Gene

mRNA expression in normal human tissues for MIR9-3 Gene

genes like me logo Genes that share expressions with MIR9-3: view

Orthologs for MIR9-3 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR9-3 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-9-1 37
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-9-3 37
  • 99 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir9-3 37
  • 99 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-9a-1 37
  • 90 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-9-1 37
  • 51 (a)
ManyToMany
chicken
(Gallus gallus)
Aves -- 37
  • 86 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-9-1 37
  • 55 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii dre-mir-9-3 37
  • 74 (a)
OneToMany
dre-mir-9-6 37
  • 77 (a)
OneToMany
dre-mir-9-7 37
  • 77 (a)
OneToMany
Species with no ortholog for MIR9-3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR9-3 Gene

ENSEMBL:
Gene Tree for MIR9-3 (if available)
TreeFam:
Gene Tree for MIR9-3 (if available)

Paralogs for MIR9-3 Gene

No data available for Paralogs for MIR9-3 Gene

Variants for MIR9-3 Gene

Sequence variations from dbSNP and Humsavar for MIR9-3 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
rs59818966 -- 89,367,376(+) AGCAT(G/T)CTTGT upstream-variant-2KB
rs74439325 -- 89,367,073(+) TAGCA(A/G)CTTGG upstream-variant-2KB
rs75526974 -- 89,366,810(+) TTCAG(C/T)TGCCA upstream-variant-2KB
rs79570836 -- 89,366,693(+) GGGCT(C/T)AAGGC upstream-variant-2KB
rs113050806 -- 89,366,970(+) ATTTA(A/G)CCAGG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR9-3 Gene

Variant ID Type Subtype PubMed ID
nsv833086 CNV Loss 17160897
dgv2433n71 CNV Loss 21882294

Relevant External Links for MIR9-3 Gene

HapMap Linkage Disequilibrium report
MIR9-3

Disorders for MIR9-3 Gene

Relevant External Links for MIR9-3

Genetic Association Database (GAD)
MIR9-3
Human Genome Epidemiology (HuGE) Navigator
MIR9-3
genes like me logo Genes that share disorders with MIR9-3: view

No data available for UniProtKB/Swiss-Prot for MIR9-3 Gene

Publications for MIR9-3 Gene

  1. Novel genetic variants in miR-191 gene and familial ovarian cancer. (PMID: 20167074) Shen J. … Zhao H. (BMC Cancer 2010) 3 49
  2. Hsa-miR-9 methylation status is associated with cancer development and metastatic recurrence in patients with clear cell renal cell carcinoma. (PMID: 20676129) Hildebrandt M.A. … Wu X. (Oncogene 2010) 3
  3. MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. (PMID: 21368052) Shibata M. … Aizawa S. (J. Neurosci. 2011) 3
  4. Real-time PCR-based analysis of the human bile microRNAome identifies miR-9 as a potential diagnostic biomarker for biliary tract cancer. (PMID: 21858175) Shigehara K. … Uchida E. (PLoS ONE 2011) 3
  5. CpG island methylation of microRNAs is associated with tumor size and recurrence of non-small-cell lung cancer. (PMID: 21917081) Kitano K. … Takai D. (Cancer Sci. 2011) 3

Products for MIR9-3 Gene

Sources for MIR9-3 Gene

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