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Aliases for MIR9-1 Gene

Subcategory (RNA class) for MIR9-1 Gene

miRNA

Quality Score for this RNA gene is

10

Aliases for MIR9-1 Gene

  • MicroRNA 9-1 2 3 5
  • Hsa-Mir-9-1 3
  • MiRNA9-1 3
  • Mir-9-1 3
  • MIRN9-1 3

External Ids for MIR9-1 Gene

Previous HGNC Symbols for MIR9-1 Gene

  • MIRN9-1

Previous GeneCards Identifiers for MIR9-1 Gene

  • GC01M154657
  • GC01M156390

Summaries for MIR9-1 Gene

Entrez Gene Summary for MIR9-1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR9-1 Gene

MIR9-1 (MicroRNA 9-1) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Cell Differentiation - Index and Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins..

fRNAdb sequence ontologies for MIR9-1 Gene

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR9-1

Additional gene information for MIR9-1 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR9-1 Gene

Genomics for MIR9-1 Gene

GeneHancer (GH) Regulatory Elements for MIR9-1 Gene

Promoters and enhancers for MIR9-1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01I156419 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE dbSUPER 550.8 -1.5 -1498 4.3 ATF1 SIN3A ZNF2 TCF12 ZNF121 GLIS2 FOS ATF7 RUNX3 SP3 MIR9-1 C1orf61 KHDC4 GON4L RRNAD1 ENSG00000271267 MSTO1 MSTO2P CCT3 PRCC
GH01I156420 Enhancer 0.3 dbSUPER 550.8 +0.9 927 0.2 EZH2 MIR9-1 C1orf61 GC01M156396
GH01I156281 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 10.1 +137.2 137171 4.4 CLOCK MLX ZFP64 DMAP1 IRF4 YY1 ZNF213 E2F8 ZNF143 SP3 SMG5 TMEM79 GLMP KHDC4 GON4L RRNAD1 YY1AP1 SLC25A44 PAQR6 BGLAP
GH01I156111 Promoter/Enhancer 2.7 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 9.3 +299.0 299040 19.4 CLOCK MLX ZFP64 FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 LMNA GON4L CLK2 RRNAD1 KHDC4 LOC246784 MSTO1 MSTO2P PRCC ISG20L2
GH01I156456 Promoter/Enhancer 2.1 FANTOM5 Ensembl ENCODE dbSUPER 11.7 -36.9 -36947 2.7 CLOCK MLX FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 ZNF416 ZNF143 ENSG00000236947 KHDC4 GON4L ENSG00000271267 RRNAD1 LOC246784 LMNA ASH1L MSTO2P PRCC
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR9-1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR9-1 Gene

Genomic Locations for MIR9-1 Gene
chr1:156,420,341-156,420,429
(GRCh38/hg38)
Size:
89 bases
Orientation:
Minus strand
chr1:156,390,133-156,390,221
(GRCh37/hg19)

Genomic View for MIR9-1 Gene

Genes around MIR9-1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR9-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR9-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR9-1 Gene

ORGUL Member Location for MIR9-1 Gene

ORGUL Member Location for MIR9-1 gene

Proteins for MIR9-1 Gene

Post-translational modifications for MIR9-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR9-1 Gene

Domains & Families for MIR9-1 Gene

Gene Families for MIR9-1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR9-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR9-1 Gene

Function for MIR9-1 Gene

Phenotypes From GWAS Catalog for MIR9-1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR9-1 Gene

Localization for MIR9-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR9-1 Gene

Pathways & Interactions for MIR9-1 Gene

genes like me logo Genes that share pathways with MIR9-1: view

Pathways by source for MIR9-1 Gene

2 BioSystems pathways for MIR9-1 Gene
1 KEGG pathway for MIR9-1 Gene

Interacting Proteins for MIR9-1 Gene

Gene Ontology (GO) - Biological Process for MIR9-1 Gene

None

No data available for SIGNOR curated interactions for MIR9-1 Gene

Drugs & Compounds for MIR9-1 Gene

No Compound Related Data Available

Transcripts for MIR9-1 Gene

fRNAdb Secondary structures for MIR9-1 Gene

  • hsa-mir-9-1_MI0000466_Homo_sapiens_miR-9-1_stem-loop_hairpin

mRNA/cDNA for MIR9-1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR9-1 Gene

No ASD Table

Relevant External Links for MIR9-1 Gene

GeneLoc Exon Structure for
MIR9-1
ECgene alternative splicing isoforms for
MIR9-1

Expression for MIR9-1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR9-1 Gene

genes like me logo Genes that share expression patterns with MIR9-1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR9-1 Gene

Orthologs for MIR9-1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR9-1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia -- 34
  • 100 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-9-1 34
  • 100 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-9-1 34
  • 100 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm25641 34
  • 100 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-9a-3 34
  • 65 (a)
ManyToMany
mdo-mir-9b 34
  • 50 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-9-1 34
  • 46 (a)
ManyToMany
chicken
(Gallus gallus)
Aves -- 34
  • 93 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-9-2 34
  • 76 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dre-mir-9-1 34
  • 68 (a)
ManyToMany
dre-mir-9-4 34
  • 64 (a)
ManyToMany
Species where no ortholog for MIR9-1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR9-1 Gene

ENSEMBL:
Gene Tree for MIR9-1 (if available)
TreeFam:
Gene Tree for MIR9-1 (if available)

Paralogs for MIR9-1 Gene

No data available for Paralogs for MIR9-1 Gene

Variants for MIR9-1 Gene

Sequence variations from dbSNP and Humsavar for MIR9-1 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1004590681 -- 156,419,847(-) T/A downstream_transcript_variant
rs1006116158 -- 156,422,272(-) T/C upstream_transcript_variant
rs1007235849 -- 156,421,327(-) A/T upstream_transcript_variant
rs1008118244 -- 156,421,468(-) C/T upstream_transcript_variant
rs1011486615 -- 156,421,904(-) C/T upstream_transcript_variant

Additional Variant Information for MIR9-1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR9-1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR9-1 Gene

Disorders for MIR9-1 Gene

Additional Disease Information for MIR9-1

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for MIR9-1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR9-1 Gene

Publications for MIR9-1 Gene

  1. Novel genetic variants in miR-191 gene and familial ovarian cancer. (PMID: 20167074) Shen J … Zhao H (BMC cancer 2010) 3 44 58
  2. Identification of tissue-specific microRNAs from mouse. (PMID: 12007417) Lagos-Quintana M … Tuschl T (Current biology : CB 2002) 1 3 58
  3. Prognostic value of microRNA-9 and microRNA-155 expression in triple-negative breast cancer. (PMID: 28882698) Jang MH … Park SY (Human pathology 2017) 3 58
  4. miR-34a and miR-9 are overexpressed and SIRT genes are downregulated in peripheral blood mononuclear cells of aging humans. (PMID: 28699360) Owczarz M … Puzianowska-Kuznicka M (Experimental biology and medicine (Maywood, N.J.) 2017) 3 58
  5. miR-9 regulates the multidrug resistance of chronic myelogenous leukemia by targeting ABCB1. (PMID: 28260112) Li Y … Jia L (Oncology reports 2017) 3 58

Products for MIR9-1 Gene

Sources for MIR9-1 Gene

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