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Aliases for MIR9-1 Gene

Subcategory (RNA class) for MIR9-1 Gene

miRNA

Quality Score for this RNA gene is

10

Aliases for MIR9-1 Gene

  • MicroRNA 9-1 2 3 5
  • Hsa-Mir-9-1 3
  • MiRNA9-1 3
  • Mir-9-1 3
  • MIRN9-1 3

External Ids for MIR9-1 Gene

Previous HGNC Symbols for MIR9-1 Gene

  • MIRN9-1

Previous GeneCards Identifiers for MIR9-1 Gene

  • GC01M154657
  • GC01M156390

Summaries for MIR9-1 Gene

Entrez Gene Summary for MIR9-1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR9-1 Gene

MIR9-1 (MicroRNA 9-1) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer and Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins..

fRNAdb sequence ontologies for MIR9-1 Gene

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR9-1

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR9-1 Gene

Genomics for MIR9-1 Gene

Regulatory Elements for MIR9-1 Gene

Enhancers for MIR9-1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01G156456 1.8 FANTOM5 ENCODE dbSUPER 11.6 -36.9 -36948 2.7 MLX CREB3L1 FEZF1 DMAP1 YY1 SLC30A9 ZNF416 ZNF143 ZNF548 ZNF263 KIAA0907 RRNAD1 ENSG00000271267 LOC246784 ARHGEF2 C1orf61 MIR9-1 SSR2 NAXE GPATCH4
GH01G156281 1.8 FANTOM5 ENCODE dbSUPER 10.1 +137.2 137172 4.4 MLX CREB3L1 ZFP64 DMAP1 YY1 ZNF143 ZNF263 SP3 NFYC TBX21 GLMP SMG5 SLC25A44 PAQR6 BGLAP ENSG00000252236 SEMA4A TSACC CCT3 KIAA0907
GH01G156111 1.9 FANTOM5 ENCODE dbSUPER 9.3 +299.0 299040 19.4 CREB3L1 MLX AGO1 ZFP64 DMAP1 FEZF1 YY1 SLC30A9 ZNF416 ZNF143 KIAA0907 MSTO2P ENSG00000271267 RRNAD1 LMNA ASH1L BGLAP LOC246784 SYT11 MEX3A
GH01G156523 1.7 FANTOM5 Ensembl ENCODE dbSUPER 10.1 -104.5 -104540 2.4 HDAC1 PKNOX1 CBX3 RAD21 YY1 TCF12 ZNF121 GATA2 EGR2 CEBPB NAXE IQGAP3 C1orf61 MIR9-1 GPATCH4 ENSG00000260460 MEF2D RRNAD1 GC01P156524
GH01G156460 1.4 Ensembl ENCODE dbSUPER 11.6 -41.3 -41334 1.7 PKNOX1 ATF1 CBX3 TBL1XR1 ZNF133 CHAMP1 TCF12 ZNF766 EGR1 GATA2 C1orf61 MIR9-1 NAXE GPATCH4 HAPLN2 MRPL24 HDGF GC01M156440 ENSG00000206651 GC01M156484
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR9-1 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR9-1 Gene

Chromosome:
1
Start:
156,420,341 bp from pter
End:
156,420,429 bp from pter
Size:
89 bases
Orientation:
Minus strand

Genomic View for MIR9-1 Gene

Genes around MIR9-1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR9-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR9-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR9-1 Gene

ORGUL Member Location for MIR9-1 Gene

ORGUL Member Location for MIR9-1 gene

Proteins for MIR9-1 Gene

Post-translational modifications for MIR9-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR9-1 Gene

Domains & Families for MIR9-1 Gene

Gene Families for MIR9-1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR9-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR9-1 Gene

Function for MIR9-1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR9-1 Gene

Localization for MIR9-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR9-1 Gene

Pathways & Interactions for MIR9-1 Gene

genes like me logo Genes that share pathways with MIR9-1: view

Pathways by source for MIR9-1 Gene

2 BioSystems pathways for MIR9-1 Gene
1 KEGG pathway for MIR9-1 Gene

Interacting Proteins for MIR9-1 Gene

Gene Ontology (GO) - Biological Process for MIR9-1 Gene

None

No data available for SIGNOR curated interactions for MIR9-1 Gene

Drugs & Compounds for MIR9-1 Gene

No Compound Related Data Available

Transcripts for MIR9-1 Gene

fRNAdb Secondary structures for MIR9-1 Gene

  • hsa-mir-9-1_MI0000466_Homo_sapiens_miR-9-1_stem-loop_hairpin

mRNA/cDNA for MIR9-1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR9-1 Gene

No ASD Table

Relevant External Links for MIR9-1 Gene

GeneLoc Exon Structure for
MIR9-1
ECgene alternative splicing isoforms for
MIR9-1

Expression for MIR9-1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR9-1 Gene

genes like me logo Genes that share expression patterns with MIR9-1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR9-1 Gene

Orthologs for MIR9-1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR9-1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia -- 35
  • 100 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-9-1 35
  • 100 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm25641 35
  • 100 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-9-1 35
  • 100 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-9a-3 35
  • 65 (a)
ManyToMany
mdo-mir-9b 35
  • 50 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-9-1 35
  • 46 (a)
ManyToMany
chicken
(Gallus gallus)
Aves -- 35
  • 93 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-9-2 35
  • 76 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dre-mir-9-1 35
  • 68 (a)
ManyToMany
dre-mir-9-4 35
  • 64 (a)
ManyToMany
Species where no ortholog for MIR9-1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR9-1 Gene

ENSEMBL:
Gene Tree for MIR9-1 (if available)
TreeFam:
Gene Tree for MIR9-1 (if available)

Paralogs for MIR9-1 Gene

No data available for Paralogs for MIR9-1 Gene

Variants for MIR9-1 Gene

Sequence variations from dbSNP and Humsavar for MIR9-1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1004590681 -- 156,419,847(+) CCGAC(A/T)TAAGC intron-variant, downstream-variant-500B, upstream-variant-2KB
rs1006116158 -- 156,422,272(+) CCTTT(C/T)AGAAT intron-variant, upstream-variant-2KB
rs1007235849 -- 156,421,327(+) CCCGG(A/T)TAAAC intron-variant, upstream-variant-2KB, utr-variant-5-prime
rs1008118244 -- 156,421,468(+) GGGCT(C/T)GGCCG intron-variant, upstream-variant-2KB, utr-variant-5-prime
rs1011486615 -- 156,421,904(+) CGGGC(C/T)GGCCG intron-variant, upstream-variant-2KB

Relevant External Links for MIR9-1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR9-1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR9-1 Gene

Disorders for MIR9-1 Gene

Relevant External Links for MIR9-1

Genetic Association Database (GAD)
MIR9-1
Human Genome Epidemiology (HuGE) Navigator
MIR9-1
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR9-1

No disorders were found for MIR9-1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR9-1 Gene

Publications for MIR9-1 Gene

  1. Novel genetic variants in miR-191 gene and familial ovarian cancer. (PMID: 20167074) Shen J. … Zhao H. (BMC Cancer 2010) 3 46 64
  2. Identification of tissue-specific microRNAs from mouse. (PMID: 12007417) Lagos-Quintana M. … Tuschl T. (Curr. Biol. 2002) 1 3 64
  3. A minicircuitry of microRNA-9-1 and RUNX1-RUNX1T1 contributes to leukemogenesis in t(8;21) acute myeloid leukemia. (PMID: 27770540) Fu L. … Yu L. (Int. J. Cancer 2017) 3 64
  4. MicroRNA-9 inhibits the gastric cancer cell proliferation by targeting TNFAIP8. (PMID: 28127811) Gao H.Y. … Pei D.S. (Cell Prolif. 2017) 3 64
  5. miR-9 regulates the multidrug resistance of chronic myelogenous leukemia by targeting ABCB1. (PMID: 28260112) Li Y. … Jia L. (Oncol. Rep. 2017) 3 64

Products for MIR9-1 Gene

Sources for MIR9-1 Gene

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