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Aliases for MIR887 Gene

Subcategory (RNA class) for MIR887 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR887 Gene

  • MicroRNA 887 2 3 5
  • Hsa-Mir-887 3
  • MIRN887 3

External Ids for MIR887 Gene

Previous HGNC Symbols for MIR887 Gene

  • MIRN887

Summaries for MIR887 Gene

Entrez Gene Summary for MIR887 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR887 Gene

MIR887 (MicroRNA 887) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins..

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR887 Gene

Genomics for MIR887 Gene

Regulatory Elements for MIR887 Gene

Enhancers for MIR887 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05F015959 0.4 ENCODE 12.4 +24.4 24446 0.7 SUPT20H RAD21 MIR887 RNA5SP178
GH05F015938 0.4 ENCODE 0.8 +4.1 4087 1.4 JUN FOS MIR887 RNA5SP178
GH05F015992 1 Ensembl ENCODE 0.2 +58.2 58201 2.0 CTCF JUN MAFG RAD21 ZNF316 JUND MAFF SMARCA4 SMC3 NFE2 RNA5SP178 MIR887
GH05F015929 0.4 ENCODE 0.4 -5.2 -5166 1.3 BHLHE40 MIR887 GC05P015848
GH05F015917 0.4 FANTOM5 0.3 -17.3 -17348 0.1 ZNF366 MIR887 GC05P015848
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR887 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR887 Gene

Chromosome:
5
Start:
15,935,182 bp from pter
End:
15,935,260 bp from pter
Size:
79 bases
Orientation:
Plus strand

Genomic View for MIR887 Gene

Genes around MIR887 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR887 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR887 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR887 Gene

Proteins for MIR887 Gene

Post-translational modifications for MIR887 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR887 Gene

Domains & Families for MIR887 Gene

Gene Families for MIR887 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR887: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR887 Gene

Function for MIR887 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR887 Gene

Localization for MIR887 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR887 Gene

Pathways & Interactions for MIR887 Gene

genes like me logo Genes that share pathways with MIR887: view

Pathways by source for MIR887 Gene

1 BioSystems pathway for MIR887 Gene

Interacting Proteins for MIR887 Gene

Gene Ontology (GO) - Biological Process for MIR887 Gene

None

No data available for SIGNOR curated interactions for MIR887 Gene

Transcripts for MIR887 Gene

mRNA/cDNA for MIR887 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR887 Gene

No ASD Table

Relevant External Links for MIR887 Gene

GeneLoc Exon Structure for
MIR887
ECgene alternative splicing isoforms for
MIR887

Expression for MIR887 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR887 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR887 Gene:

MIR887
genes like me logo Genes that share expression patterns with MIR887: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR887 Gene

Orthologs for MIR887 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR887 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-887 35
  • 100 (a)
OneToOne
Species where no ortholog for MIR887 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR887 Gene

ENSEMBL:
Gene Tree for MIR887 (if available)
TreeFam:
Gene Tree for MIR887 (if available)

Paralogs for MIR887 Gene

No data available for Paralogs for MIR887 Gene

Variants for MIR887 Gene

Sequence variations from dbSNP and Humsavar for MIR887 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs111860336 -- 15,933,846(+) GTGTC(C/T)GAAGT intron-variant, upstream-variant-2KB
rs112038088 -- 15,935,319(+) GGAAT(C/T)GACTG intron-variant, downstream-variant-500B
rs112779168 -- 15,935,374(+) GAGTG(A/G)ACGGG intron-variant, downstream-variant-500B
rs114287388 -- 15,935,585(+) TGGCA(A/G)ATAGG intron-variant, downstream-variant-500B
rs114555764 -- 15,933,481(+) ATAGA(A/C)AAACA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR887 Gene

Variant ID Type Subtype PubMed ID
nsv4735 CNV deletion 18451855
nsv597292 CNV gain 21841781
nsv830216 CNV loss 17160897

Relevant External Links for MIR887 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR887

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR887 Gene

Disorders for MIR887 Gene

Relevant External Links for MIR887

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR887

No disorders were found for MIR887 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR887 Gene

Publications for MIR887 Gene

  1. Down-regulation of MicroRNAs (MiRs) 203, 887, 3619 and 182 Prevents Vimentin-triggered, Phospholipase D (PLD)-mediated Cancer Cell Invasion. (PMID: 26567912) Fite K. … Gomez-Cambronero J. (J. Biol. Chem. 2016) 3 64
  2. A genetic variant of MDM4 influences regulation by multiple microRNAs in prostate cancer. (PMID: 25670033) Stegeman S. … Batra J. (Endocr. Relat. Cancer 2015) 3 64
  3. Birth and expression evolution of mammalian microRNA genes. (PMID: 23034410) Meunier J. … Kaessmann H. (Genome Res. 2013) 3 64
  4. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3 64
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR887 Gene

Sources for MIR887 Gene

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