Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR885 Gene

Subcategory (RNA class) for MIR885 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR885 Gene

  • MicroRNA 885 2 3 5
  • Hsa-Mir-885 3
  • Mir-885 3
  • MIRN885 3

External Ids for MIR885 Gene

Previous HGNC Symbols for MIR885 Gene

  • MIRN885

Summaries for MIR885 Gene

Entrez Gene Summary for MIR885 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR885 Gene

MIR885 (MicroRNA 885) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR885 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR885 Gene

Genomics for MIR885 Gene

GeneHancer (GH) Regulatory Elements for MIR885 Gene

Promoters and enhancers for MIR885 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH03I010394 Enhancer 0.6 ENCODE dbSUPER 550.8 -0.6 -612 0.8 POU5F1 CTBP2 MIR885 GHRL GC03P010586 ATP2B2
GH03I010395 Enhancer 0.4 ENCODE dbSUPER 550.8 -1.3 -1270 0.2 MIR885 GC03P010586 ATP2B2
GH03I010436 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 11.5 -43.4 -43359 2.8 PKNOX1 KLF17 RAD21 ZNF335 TCF12 EGR1 ZSCAN5C SCRT2 ATF7 ETV6 MIR885 SEC13 TATDN2 GC03P010586 GC03M010552 ATP2B2
GH03I010460 Enhancer 1 ENCODE 11.4 -65.8 -65750 0.2 CLOCK MLX ZFP64 ARID4B SIN3A DMAP1 ZBTB7B IRF4 SLC30A9 ZNF766 MIR885 GHRLOS GC03P010586 GC03M010552 ATP2B2
GH03I010370 Enhancer 0.9 ENCODE dbSUPER 11.5 +23.9 23930 0.2 HDAC1 BACH1 FOSL1 TCF12 CTBP1 ZNF316 VEZF1 CBFA2T2 FOS NFE2 MIR885 GC03M010355 MIR378B ATP2B2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR885 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR885 Gene

Genomic Locations for MIR885 Gene
chr3:10,394,489-10,394,562
(GRCh38/hg38)
Size:
74 bases
Orientation:
Minus strand
chr3:10,436,173-10,436,246
(GRCh37/hg19)

Genomic View for MIR885 Gene

Genes around MIR885 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR885 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR885 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR885 Gene

Proteins for MIR885 Gene

Post-translational modifications for MIR885 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR885 Gene

Domains & Families for MIR885 Gene

Gene Families for MIR885 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR885: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR885 Gene

Function for MIR885 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR885 Gene

Localization for MIR885 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR885 Gene

Pathways & Interactions for MIR885 Gene

SuperPathways for MIR885 Gene

No Data Available

Interacting Proteins for MIR885 Gene

Gene Ontology (GO) - Biological Process for MIR885 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR885 Gene

Drugs & Compounds for MIR885 Gene

No Compound Related Data Available

Transcripts for MIR885 Gene

mRNA/cDNA for MIR885 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR885 Gene

No ASD Table

Relevant External Links for MIR885 Gene

GeneLoc Exon Structure for
MIR885
ECgene alternative splicing isoforms for
MIR885

Expression for MIR885 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR885 Gene:

MIR885
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR885 Gene

Orthologs for MIR885 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR885 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-885 34
  • 100 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-885 34
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-885 34
  • 97 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 53 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-885 34
  • 51 (a)
OneToOne
Species where no ortholog for MIR885 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR885 Gene

ENSEMBL:
Gene Tree for MIR885 (if available)
TreeFam:
Gene Tree for MIR885 (if available)

Paralogs for MIR885 Gene

No data available for Paralogs for MIR885 Gene

Variants for MIR885 Gene

Sequence variations from dbSNP and Humsavar for MIR885 Gene

SNP ID Clin Chr 03 pos Variation AA Info Type
rs1001290257 -- 10,396,255(-) T/C upstream_transcript_variant
rs1002975303 -- 10,394,036(-) G/A downstream_transcript_variant
rs1007313780 -- 10,395,970(-) T/C upstream_transcript_variant
rs1007918602 -- 10,394,618(-) G/C upstream_transcript_variant
rs1008482568 -- 10,394,326(-) A/C downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR885 Gene

Variant ID Type Subtype PubMed ID
dgv762e201 CNV deletion 23290073
esv4117 OTHER complex 18987735
nsv1073204 CNV deletion 25765185
nsv1121603 CNV deletion 24896259
nsv436362 CNV deletion 17901297
nsv436869 CNV insertion 17901297
nsv508903 CNV insertion 20534489

Additional Variant Information for MIR885 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR885

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR885 Gene

Disorders for MIR885 Gene

Additional Disease Information for MIR885

No disorders were found for MIR885 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR885 Gene

Publications for MIR885 Gene

  1. p73 and IGF1R Regulate Emergence of Aggressive Cancer Stem-like Features via miR-885-5p Control. (PMID: 26554827) Meier C … Pützer BM (Cancer research 2016) 3 58
  2. Circulating microRNA expression profiles in pre-eclampsia: evidence of increased miR-885-5p levels. (PMID: 26853698) Sandrim VC … Cavalli RC (BJOG : an international journal of obstetrics and gynaecology 2016) 3 58
  3. Identification of a metastasis-specific MicroRNA signature in human colorectal cancer. (PMID: 25663689) Hur K … Goel A (Journal of the National Cancer Institute 2015) 3 58
  4. MicroRNA-885-3p inhibits the growth of HT-29 colon cancer cell xenografts by disrupting angiogenesis via targeting BMPR1A and blocking BMP/Smad/Id1 signaling. (PMID: 24882581) Xiao F … Ding K (Oncogene 2015) 3 58
  5. Signature of circulating microRNAs in osteoarthritis. (PMID: 24515954) Beyer C … Kiechl S (Annals of the rheumatic diseases 2015) 3 58

Products for MIR885 Gene

Sources for MIR885 Gene

Content
Loading form....