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Aliases for MIR877 Gene

Subcategory (RNA class) for MIR877 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR877 Gene

  • MicroRNA 877 2 3
  • MIRN877 3 6
  • Hsa-Mir-877 3
  • MiRNA877 3

External Ids for MIR877 Gene

Previous HGNC Symbols for MIR877 Gene

  • MIRN877

Previous GeneCards Identifiers for MIR877 Gene

  • GC06P030662
  • GC06P030663
  • GC06P030552
  • GC06P030354

Summaries for MIR877 Gene

Entrez Gene Summary for MIR877 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR877 Gene

MIR877 (MicroRNA 877) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR877 Gene

Genomics for MIR877 Gene

Genomic Location for MIR877 Gene

Start:
30,584,312 bp from pter
End:
30,584,425 bp from pter
Size:
114 bases
Orientation:
Plus strand

Genomic View for MIR877 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR877 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

No data available for Regulatory Elements for MIR877 Gene

Proteins for MIR877 Gene

Post-translational modifications for MIR877 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR877 Gene

Domains for MIR877 Gene

Gene Families for MIR877 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR877: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR877 Gene

Function for MIR877 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR877 Gene

Localization for MIR877 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR877 Gene

Pathways for MIR877 Gene

SuperPathways for MIR877 Gene

No Data Available

Interacting Proteins for MIR877 Gene

Gene Ontology (GO) - Biological Process for MIR877 Gene

None

No data available for Pathways by source for MIR877 Gene

Transcripts for MIR877 Gene

mRNA/cDNA for MIR877 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR877 Gene

No ASD Table

Relevant External Links for MIR877 Gene

GeneLoc Exon Structure for
MIR877
ECgene alternative splicing isoforms for
MIR877

Expression for MIR877 Gene

mRNA expression in normal human tissues for MIR877 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

genes like me logo Genes that share expressions with MIR877: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR877 Gene

Orthologs for MIR877 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR877 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 83 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-877 36
  • 75 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 36
  • 73 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir877 36
  • 84 (a)
OneToOne
Species with no ortholog for MIR877:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR877 Gene

ENSEMBL:
Gene Tree for MIR877 (if available)
TreeFam:
Gene Tree for MIR877 (if available)

Paralogs for MIR877 Gene

No data available for Paralogs for MIR877 Gene

Variants for MIR877 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR877 Gene

Variant ID Type Subtype PubMed ID
esv2731791 CNV Deletion 23290073
nsv884086 CNV Gain 21882294
esv2670269 CNV Deletion 23128226
nsv884091 CNV Loss 21882294
nsv5244 CNV Loss 18451855

Relevant External Links for MIR877 Gene

HapMap Linkage Disequilibrium report
MIR877

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for MIR877 Gene

Disorders for MIR877 Gene

No disorders were found for MIR877 Gene.

No data available for UniProtKB/Swiss-Prot for MIR877 Gene

Publications for MIR877 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis. (PMID: 16954537) Berezikov E. … Cuppen E. (Genome Res. 2006) 3
  3. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  4. Mammalian mirtron genes. (PMID: 17964270) Berezikov E. … Lai E.C. (Mol. Cell 2007) 3

Products for MIR877 Gene

Sources for MIR877 Gene

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