Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR7973-2 Gene

Subcategory (RNA class) for MIR7973-2 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR7973-2 Gene

  • MicroRNA 7973-2 2 3 5
  • MicroRNA Mir-7973-2 3
  • Hsa-Mir-7973-2 3

External Ids for MIR7973-2 Gene

Previous GeneCards Identifiers for MIR7973-2 Gene

  • GC15U901672

Summaries for MIR7973-2 Gene

Entrez Gene Summary for MIR7973-2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR7973-2 Gene

MIR7973-2 (MicroRNA 7973-2) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR7973-2 Gene

Genomics for MIR7973-2 Gene

Regulatory Elements for MIR7973-2 Gene

Enhancers for MIR7973-2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH15G051314 1.4 FANTOM5 ENCODE dbSUPER 0.7 -1.5 -1528 3.0 ELF3 MLX ARID4B DMAP1 RAD21 ZNF48 ZSCAN9 RARA GATA4 CREM CYP19A1 GLDN GNB5 AP4E1 ENSG00000259306 MIR7973-2
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR7973-2 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR7973-2 Gene

Chromosome:
15
Start:
51,314,032 bp from pter
End:
51,314,107 bp from pter
Size:
76 bases
Orientation:
Minus strand

Genomic View for MIR7973-2 Gene

Genes around MIR7973-2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR7973-2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR7973-2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR7973-2 Gene

ORGUL Member Location for MIR7973-2 Gene

ORGUL Member Location for MIR7973-2 gene

Proteins for MIR7973-2 Gene

Post-translational modifications for MIR7973-2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR7973-2 Gene

Domains & Families for MIR7973-2 Gene

Gene Families for MIR7973-2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR7973-2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR7973-2 Gene

Function for MIR7973-2 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR7973-2 Gene

Localization for MIR7973-2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR7973-2 Gene

Pathways & Interactions for MIR7973-2 Gene

SuperPathways for MIR7973-2 Gene

No Data Available

Interacting Proteins for MIR7973-2 Gene

Gene Ontology (GO) - Biological Process for MIR7973-2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR7973-2 Gene

Drugs & Compounds for MIR7973-2 Gene

No Compound Related Data Available

Transcripts for MIR7973-2 Gene

mRNA/cDNA for MIR7973-2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR7973-2 Gene

No ASD Table

Relevant External Links for MIR7973-2 Gene

GeneLoc Exon Structure for
MIR7973-2
ECgene alternative splicing isoforms for
MIR7973-2

Expression for MIR7973-2 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR7973-2 Gene

Orthologs for MIR7973-2 Gene

Evolution for MIR7973-2 Gene

ENSEMBL:
Gene Tree for MIR7973-2 (if available)
TreeFam:
Gene Tree for MIR7973-2 (if available)

No data available for Orthologs for MIR7973-2 Gene

Paralogs for MIR7973-2 Gene

No data available for Paralogs for MIR7973-2 Gene

Variants for MIR7973-2 Gene

Sequence variations from dbSNP and Humsavar for MIR7973-2 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs1001739444 -- 51,313,851(+) GGGCT(-/G)GGGTG intron-variant, downstream-variant-500B, upstream-variant-2KB
rs1002782544 -- 51,316,011(+) AAGGA(A/G)AAAGC intron-variant, upstream-variant-2KB
rs1010291751 -- 51,316,030(+) AGTCC(A/G)GGAAC intron-variant, upstream-variant-2KB
rs1011465112 -- 51,315,823(+) TCTTC(A/G)TGTTT intron-variant, upstream-variant-2KB
rs1011552915 -- 51,314,712(+) CTTCT(A/G)GAAAG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR7973-2 Gene

Variant ID Type Subtype PubMed ID
dgv4526n54 CNV gain 21841781
esv2760031 CNV gain 17122850
esv34532 CNV gain 17911159
esv3636461 CNV gain 21293372
nsv1047443 CNV gain 25217958
nsv471243 CNV gain 18288195

Relevant External Links for MIR7973-2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR7973-2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR7973-2 Gene

Disorders for MIR7973-2 Gene

Relevant External Links for MIR7973-2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR7973-2

No disorders were found for MIR7973-2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR7973-2 Gene

Publications for MIR7973-2 Gene

  1. Research resource: small RNA-seq of human granulosa cells reveals miRNAs in FSHR and aromatase genes. (PMID: 23660593) Velthut-Meikas A. … Salumets A. (Mol. Endocrinol. 2013) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR7973-2 Gene

Sources for MIR7973-2 Gene

Content
Loading form....