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Aliases for MIR769 Gene

Subcategory (RNA class) for MIR769 Gene

miRNA

Quality Score for this RNA gene is

13

Aliases for MIR769 Gene

  • MicroRNA 769 2 3 5
  • Hsa-Mir-769 3
  • Mir-769 3
  • MIRN769 3

External Ids for MIR769 Gene

ORGUL Members for MIR769 Gene

Previous HGNC Symbols for MIR769 Gene

  • MIRN769

Previous GeneCards Identifiers for MIR769 Gene

  • GC19P051215
  • GC19P046522

Summaries for MIR769 Gene

Entrez Gene Summary for MIR769 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR769 Gene

MIR769 (MicroRNA 769) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins..

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR769 Gene

Genomics for MIR769 Gene

Regulatory Elements for MIR769 Gene

Enhancers for MIR769 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19F046065 0.7 ENCODE 11.5 +46.8 46786 0.2 CTCF STAT1 BDP1 JUN CEBPB DPF2 JUND GATA3 POLR3A STAT3 IRF2BP1 PPP1R37 PGLYRP1 MIR769 HIF3A PIR33092 PIR35316
GH19F045952 0.9 Ensembl ENCODE 11.3 -64.2 -64244 4.7 ATF1 ZNF133 ARID4B SIN3A GLI4 ZNF2 GLIS2 CBX5 ZNF143 SP3 IGFL4 CCDC61 LOC105372421 PPP5D1 MYPOP MIR769 PGLYRP1 FOXA3 SYMPK HIF3A
GH19F046262 1.1 Ensembl ENCODE 11.1 +244.3 244269 0.8 HDGF FEZF1 ELK1 ZNF143 FOS ZNF263 SP3 YY2 JUNB TSHZ1 CCDC61 CCDC9 FBXO46 ZC3H4 ENSG00000269148 SLC1A5 HIF3A IGFL4 ENSG00000268810 PGLYRP1
GH19F046265 0.4 ENCODE 11.1 +246.5 246507 0.2 CTCF MAX RAD21 SCRT2 ZNF143 SMC3 ZBTB20 SCRT1 ZNF654 TRIM22 HIF3A IGFL4 MIR769 PGLYRP1 CCDC61 NOVA2 IGFL1P2
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR769 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR769 Gene

Chromosome:
19
Start:
46,018,932 bp from pter
End:
46,019,049 bp from pter
Size:
118 bases
Orientation:
Plus strand

Genomic View for MIR769 Gene

Genes around MIR769 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR769 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR769 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR769 Gene

Proteins for MIR769 Gene

Post-translational modifications for MIR769 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR769 Gene

Domains & Families for MIR769 Gene

Gene Families for MIR769 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR769: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR769 Gene

Function for MIR769 Gene

Animal Model Products

miRNA for MIR769 Gene

miRTarBase miRNAs that target MIR769

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MIR769 Gene

Localization for MIR769 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR769 Gene

Pathways & Interactions for MIR769 Gene

genes like me logo Genes that share pathways with MIR769: view

Pathways by source for MIR769 Gene

1 BioSystems pathway for MIR769 Gene

Interacting Proteins for MIR769 Gene

Gene Ontology (GO) - Biological Process for MIR769 Gene

None

No data available for SIGNOR curated interactions for MIR769 Gene

Transcripts for MIR769 Gene

mRNA/cDNA for MIR769 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR769 Gene

No ASD Table

Relevant External Links for MIR769 Gene

GeneLoc Exon Structure for
MIR769
ECgene alternative splicing isoforms for
MIR769

Expression for MIR769 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR769 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR769 Gene:

MIR769
genes like me logo Genes that share expression patterns with MIR769: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR769 Gene

Orthologs for MIR769 Gene

Evolution for MIR769 Gene

ENSEMBL:
Gene Tree for MIR769 (if available)
TreeFam:
Gene Tree for MIR769 (if available)

No data available for Orthologs for MIR769 Gene

Paralogs for MIR769 Gene

No data available for Paralogs for MIR769 Gene

Variants for MIR769 Gene

Sequence variations from dbSNP and Humsavar for MIR769 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1054881 -- 46,018,518(+) GGGGT(C/T)TCAGG upstream-variant-2KB, utr-variant-3-prime
rs1054882 -- 46,018,548(+) GCCCT(C/T)TCCCC upstream-variant-2KB, utr-variant-3-prime
rs11083793 -- 46,017,687(+) GCACC(A/T)GGCCT intron-variant, upstream-variant-2KB
rs111751953 -- 46,016,969(+) GCGGT(C/T)ACGCC intron-variant, upstream-variant-2KB
rs112534560 -- 46,019,320(+) CCCGG(C/T)GTCCT downstream-variant-500B, reference, missense

Relevant External Links for MIR769 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR769

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR769 Gene

Disorders for MIR769 Gene

Relevant External Links for MIR769

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR769

No disorders were found for MIR769 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR769 Gene

Publications for MIR769 Gene

  1. MicroRNA-769-3p down-regulates NDRG1 and enhances apoptosis in MCF-7 cells during reoxygenation. (PMID: 25081069) Luo E.C. … Lai L.C. (Sci Rep 2014) 3 64
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64
  4. Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis. (PMID: 16954537) Berezikov E. … Cuppen E. (Genome Res. 2006) 3 64

Products for MIR769 Gene

Sources for MIR769 Gene

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