Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR766 Gene

Subcategory (RNA class) for MIR766 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR766 Gene

  • MicroRNA 766 2 3 5
  • Hsa-Mir-766 3
  • Mir-766 3
  • MIRN766 3

External Ids for MIR766 Gene

Previous HGNC Symbols for MIR766 Gene

  • MIRN766

Previous GeneCards Identifiers for MIR766 Gene

  • GC0XM118665
  • GC0XM118780

Summaries for MIR766 Gene

Entrez Gene Summary for MIR766 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR766 Gene

MIR766 (MicroRNA 766) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR766 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR766 Gene

Genomics for MIR766 Gene

GeneHancer (GH) Regulatory Elements for MIR766 Gene

Promoters and enhancers for MIR766 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH0XI119646 Enhancer 1 ENCODE dbSUPER 550.8 -0.7 -739 2.8 PKNOX1 SMAD1 BMI1 BATF RAD21 KLF5 IRF4 ZNF207 ZNF143 ATF7 MIR766 GC0XM119648 GC0XM119647 CXorf56 SEPT6
GH0XI119674 Promoter/Enhancer 2.8 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 13.9 -37.9 -37856 20.2 HDGF PKNOX1 SMAD1 ARNT ZFP64 ARID4B FEZF1 IRF4 YY1 POLR2B SEPT6 NKAPP1 EEF1A1P30 CUL4B UPF3B NKAP NKRF MIR766 CXorf56 LINC01402
GH0XI119753 Promoter/Enhancer 2.2 EPDnew FANTOM5 Ensembl ENCODE 12.8 -110.2 -110204 6.9 HDGF PKNOX1 ARID4B SIN3A DMAP1 IRF4 ZNF48 ZNF121 GLIS2 ZNF143 SOWAHD RNF113A NDUFA1 MIR766 EEF1A1P30 NKAPP1 UPF3B SEPT6 ZBTB33 PIR44405
GH0XI119669 Enhancer 1.1 Ensembl ENCODE dbSUPER 14.1 -22.9 -22919 1.4 SOX13 FOXA2 SAP130 ARID4B DMAP1 ZNF644 ZNF48 TEAD3 POLR2A RCOR1 MIR766 SEPT6 GC0XM119647
GH0XI119666 Enhancer 0.9 ENCODE dbSUPER 14.1 -20.6 -20645 1.8 KLF1 MAZ USF1 ZNF189 ZNF398 FEZF1 ZIC2 ZNF335 ZFHX2 GLIS1 MIR766 GC0XM119647 SEPT6
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR766 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR766 Gene

Genomic Locations for MIR766 Gene
chrX:119,646,738-119,646,848
(GRCh38/hg38)
Size:
111 bases
Orientation:
Minus strand
chrX:118,780,701-118,780,811
(GRCh37/hg19)

Genomic View for MIR766 Gene

Genes around MIR766 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR766 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR766 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR766 Gene

Proteins for MIR766 Gene

Post-translational modifications for MIR766 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR766 Gene

Domains & Families for MIR766 Gene

Gene Families for MIR766 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR766: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR766 Gene

Function for MIR766 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR766 Gene

Localization for MIR766 Gene

Gene Ontology (GO) - Cellular Components for MIR766 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 26646931
genes like me logo Genes that share ontologies with MIR766: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR766 Gene

Pathways & Interactions for MIR766 Gene

SuperPathways for MIR766 Gene

No Data Available

Interacting Proteins for MIR766 Gene

Gene Ontology (GO) - Biological Process for MIR766 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR766 Gene

Drugs & Compounds for MIR766 Gene

No Compound Related Data Available

Transcripts for MIR766 Gene

mRNA/cDNA for MIR766 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR766 Gene

No ASD Table

Relevant External Links for MIR766 Gene

GeneLoc Exon Structure for
MIR766
ECgene alternative splicing isoforms for
MIR766

Expression for MIR766 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR766 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR766 Gene:

MIR766
genes like me logo Genes that share expression patterns with MIR766: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR766 Gene

Orthologs for MIR766 Gene

Evolution for MIR766 Gene

ENSEMBL:
Gene Tree for MIR766 (if available)
TreeFam:
Gene Tree for MIR766 (if available)

No data available for Orthologs for MIR766 Gene

Paralogs for MIR766 Gene

No data available for Paralogs for MIR766 Gene

Variants for MIR766 Gene

Sequence variations from dbSNP and Humsavar for MIR766 Gene

SNP ID Clin Chr 0X pos Variation AA Info Type
rs1002476690 -- 119,646,378(-) G/C downstream_transcript_variant
rs1002768787 -- 119,646,943(-) A/T upstream_transcript_variant
rs1003878382 -- 119,646,363(-) C/A downstream_transcript_variant
rs1005046136 -- 119,647,276(-) G/A upstream_transcript_variant
rs1009009134 -- 119,647,143(-) T/C upstream_transcript_variant

Additional Variant Information for MIR766 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR766

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR766 Gene

Disorders for MIR766 Gene

Additional Disease Information for MIR766

No disorders were found for MIR766 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR766 Gene

Publications for MIR766 Gene

  1. DNA-methylation-mediated repression of miR-766-3p promotes cell proliferation via targeting SF2 expression in renal cell carcinoma. (PMID: 28657135) Chen C … Zheng J (International journal of cancer 2017) 3 58
  2. Association of MicroRNAs and YRNAs With Platelet Function. (PMID: 26646931) Kaudewitz D … Mayr M (Circulation research 2016) 3 58
  3. MiR-339 and especially miR-766 reactivate the expression of tumor suppressor genes in colorectal cancer cell lines through DNA methyltransferase 3B gene inhibition. (PMID: 27668319) Afgar A … Teimoori-Toolabi L (Cancer biology & therapy 2016) 3 58
  4. Human aldosterone synthase gene polymorphism promotes miRNA binding and regulates gene expression. (PMID: 25351194) Maharjan S … Kumar A (Physiological genomics 2014) 3 58
  5. The role of SIRT6 protein in aging and reprogramming of human induced pluripotent stem cells. (PMID: 23653361) Sharma A … Wu JC (The Journal of biological chemistry 2013) 3 58

Products for MIR766 Gene

Sources for MIR766 Gene

Content
Loading form....