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Aliases for MIR762 Gene

Subcategory (RNA class) for MIR762 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR762 Gene

  • MicroRNA 762 2 3 5
  • Hsa-Mir-762 3

External Ids for MIR762 Gene

Previous GeneCards Identifiers for MIR762 Gene

  • GC00U923293
  • GC16M030846
  • GC16P030909

Summaries for MIR762 Gene

Entrez Gene Summary for MIR762 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR762 Gene

MIR762 (MicroRNA 762) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR762 Gene

Genomics for MIR762 Gene

Regulatory Elements for MIR762 Gene

Enhancers for MIR762 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH16G030813 1.7 FANTOM5 Ensembl ENCODE 11.7 -79.7 -79712 2.1 HDGF HNRNPUL1 FOXA2 MLX CREB3L1 AGO1 ZFP64 SIN3A ARID4B DMAP1 HSD3B7 ZNF629 MIR762 CTF1 BCL7C ENSG00000274848
GH16G030805 1.4 Ensembl ENCODE 11.4 -87.6 -87587 2.6 HDGF MLX CREB3L1 ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 ZBTB7B ZNF720 HSD3B7 CCDC189 RNF40 ZNF785 MIR762 BCL7C CTF1 ZNF668 SRCAP
GH16G030939 1.3 Ensembl ENCODE 11.3 +47.6 47634 3.6 HDGF PKNOX1 AGO1 WRNIP1 ARID4B ZNF2 YY1 ZNF416 ZNF207 ZNF143 HSD3B7 ZNF668 ZNF720 ZNF785 KAT8 ZNF646 CTF1 MIR762 BCL7C RNF40
GH16G030865 1.1 FANTOM5 12.3 -28.7 -28676 0.1 HDGF PKNOX1 ARNT TCF12 ZNF766 GATA2 KLF13 DEK NCOA1 TBX21 MIR762 BCL7C CTF1 ZNF629 SRCAP SNORA30 MIR762HG LOC647086
GH16G030808 1.1 Ensembl ENCODE 11.7 -85.1 -85138 1.5 HDAC1 ELF3 HDGF PKNOX1 ATF1 FOXA2 TBL1XR1 ZSCAN9 RARA ZNF121 ZNF629 CCDC189 RNF40 MIR762 CTF1 BCL7C SRCAP SNORA30 ENSG00000274848
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR762 on UCSC Golden Path with GeneCards custom track

Promoters for MIR762 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000280305 -3 1001 HDGF FOXA2 MLX ARNT CREB3L1 AGO1 ZFP64 ARID4B SIN3A DMAP1

Genomic Location for MIR762 Gene

Chromosome:
16
Start:
30,893,903 bp from pter
End:
30,893,985 bp from pter
Size:
83 bases
Orientation:
Plus strand

Genomic View for MIR762 Gene

Genes around MIR762 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR762 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR762 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR762 Gene

Proteins for MIR762 Gene

Post-translational modifications for MIR762 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR762 Gene

Domains & Families for MIR762 Gene

Gene Families for MIR762 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR762: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR762 Gene

Function for MIR762 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR762 Gene

Localization for MIR762 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR762 Gene

Pathways & Interactions for MIR762 Gene

SuperPathways for MIR762 Gene

No Data Available

Interacting Proteins for MIR762 Gene

Gene Ontology (GO) - Biological Process for MIR762 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR762 Gene

Drugs & Compounds for MIR762 Gene

No Compound Related Data Available

Transcripts for MIR762 Gene

mRNA/cDNA for MIR762 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR762 Gene

No ASD Table

Relevant External Links for MIR762 Gene

GeneLoc Exon Structure for
MIR762
ECgene alternative splicing isoforms for
MIR762

Expression for MIR762 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR762 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR762 Gene:

MIR762
genes like me logo Genes that share expression patterns with MIR762: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR762 Gene

Orthologs for MIR762 Gene

Evolution for MIR762 Gene

ENSEMBL:
Gene Tree for MIR762 (if available)
TreeFam:
Gene Tree for MIR762 (if available)

No data available for Orthologs for MIR762 Gene

Paralogs for MIR762 Gene

No data available for Paralogs for MIR762 Gene

Variants for MIR762 Gene

Sequence variations from dbSNP and Humsavar for MIR762 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs1000000851 -- 30,894,082(+) CGTCC(A/C)CAACG intron-variant, downstream-variant-500B, upstream-variant-2KB, utr-variant-5-prime
rs1000096903 -- 30,894,283(+) GACGG(A/G)CGCGC intron-variant, downstream-variant-500B, upstream-variant-2KB, utr-variant-5-prime
rs1000768790 -- 30,893,148(+) GTCAG(C/T)GTGGG intron-variant, upstream-variant-2KB
rs1001222389 -- 30,893,497(+) TATGA(C/T)TTGGG intron-variant, upstream-variant-2KB
rs1001958088 -- 30,893,570(+) TCAGA(A/G)CCCTG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR762 Gene

Variant ID Type Subtype PubMed ID
dgv35n68 CNV loss 17160897
nsv457483 CNV loss 19166990
nsv571820 CNV loss 21841781
nsv833189 CNV loss 17160897
nsv953802 CNV deletion 24416366

Relevant External Links for MIR762 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR762

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR762 Gene

Disorders for MIR762 Gene

Relevant External Links for MIR762

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR762

No disorders were found for MIR762 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR762 Gene

Publications for MIR762 Gene

  1. microRNA-762 promotes breast cancer cell proliferation and invasion by targeting IRF7 expression. (PMID: 26597380) Li Y. … Yun J. (Cell Prolif. 2015) 3 64
  2. MicroRNA-762 is upregulated in human corneal epithelial cells in response to tear fluid and Pseudomonas aeruginosa antigens and negatively regulates the expression of host defense genes encoding RNase7 and ST2. (PMID: 23469087) Mun J. … Fleiszig S. (PLoS ONE 2013) 3 64
  3. miRNAminer: a tool for homologous microRNA gene search. (PMID: 18215311) Artzi S. … Shomron N. (BMC Bioinformatics 2008) 3 64
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64
  5. Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis. (PMID: 16954537) Berezikov E. … Cuppen E. (Genome Res. 2006) 3 64

Products for MIR762 Gene

Sources for MIR762 Gene

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