Aliases for MIR718 Gene
Subcategory (RNA class) for MIR718 Gene
Quality Score for this RNA gene is
External Ids for MIR718 Gene
- HGNC: 37317
- Entrez Gene: 100313781
- Ensembl: ENSG00000284286
- OMIM: 300929
- miRBase: hsa-mir-718
ORGUL Members for MIR718 Gene
Previous GeneCards Identifiers for MIR718 Gene
- GC00U930648
- GC0XM153286
Summaries for MIR718 Gene
-
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
GeneCards Summary for MIR718 Gene
MIR718 (MicroRNA 718) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Apoptosis Modulation and Signaling and IL-1 signaling pathway.
Additional gene information for MIR718 Gene
No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR718 Gene
Genomics for MIR718 Gene
GeneHancer (GH) Regulatory Elements for MIR718 Gene
Regulatory Element Products
Genomic Locations for MIR718 Gene
- chrX:154,019,920-154,019,989
- (GRCh38/hg38)
- Size:
- 70 bases
- Orientation:
- Minus strand
- chrX:153,285,371-153,285,440
- (GRCh37/hg19)
Genomic View for MIR718 Gene
- Cytogenetic band:
-
- Xq28 by Ensembl
- Xq28 by Entrez Gene
- Xq28 by HGNC


RefSeq DNA sequence for MIR718 Gene
Proteins for MIR718 Gene
Post-translational modifications for MIR718 Gene
Antibody Products
- Search GeneTex for Antibodies for MIR718
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR718
- Origene Custom Protein Services for MIR718
- Search GeneTex for Proteins for MIR718
No data available for DME Specific Peptides for MIR718 Gene
Domains & Families for MIR718 Gene
Gene Families for MIR718 Gene
- HGNC:
Graphical View of Domain Structure for InterPro Entry
No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR718 Gene
Function for MIR718 Gene
Phenotypes From GWAS Catalog for MIR718 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR718
-
- Search ViGene Biosciences for MIR718
CRISPR Products
- Browse CRISPR knockouts for MIR718
- Applied Biological Materials CRISPR for MIR718
-
Vectors and viruses for KO, Activation, Repression, and more
Inhibitory RNA Products
- Search ViGene Biosciences for MIR718
Clone Products
- GenScript: Custom all cDNA clones Services for MIR718
- VectorBuilder custom plasmid, inducible vectors for MIR718
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR718
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for MIR718
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR718 Gene
Localization for MIR718 Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR718 Gene
Pathways & Interactions for MIR718 Gene
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Activated TLR4 signalling | ||
2 | Diseases associated with the TLR signaling cascade | ||
3 | p75 NTR receptor-mediated signalling | ||
4 | IL-1 signaling pathway | ||
5 | Cytokine Signaling in Immune system |
Pathways by source for MIR718 Gene
11 BioSystems pathways for MIR718 Gene
37 Reactome pathways for MIR718 Gene
Interacting Proteins for MIR718 Gene
No data available for SIGNOR curated interactions for MIR718 Gene
Transcripts for MIR718 Gene
mRNA/cDNA for MIR718 Gene
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
- Browse CRISPR knockouts for MIR718
- Applied Biological Materials CRISPR for MIR718
-
Vectors and viruses for KO, Activation, Repression, and more
Inhibitory RNA Products
- Search ViGene Biosciences for MIR718
Clone Products
- GenScript: Custom all cDNA clones Services for MIR718
- VectorBuilder custom plasmid, inducible vectors for MIR718
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR718
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for MIR718
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for MIR718 Gene
NURSA nuclear receptor signaling pathways regulating expression of MIR718 Gene:
MIR718Primer Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR718 Gene
Orthologs for MIR718 Gene
No data available for Orthologs for MIR718 Gene
Paralogs for MIR718 Gene
No data available for Paralogs for MIR718 Gene
Variants for MIR718 Gene
SNP ID | Clin | Chr 0X pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs267608360 | benign, not specified | 154,021,864(-) | GGGGGGGGGG/GGGGGGGG/GGGGGGGGG/GGGGGGGGGGG | upstream_transcript_variant | |
rs267608391 | benign, not specified | 154,021,867(-) | G/C | upstream_transcript_variant | |
rs1005276589 | -- | 154,020,892(-) | C/T | upstream_transcript_variant | |
rs1005616683 | -- | 154,020,460(-) | C/T | upstream_transcript_variant | |
rs1012794698 | -- | 154,021,608(-) | A/G | upstream_transcript_variant |
Additional Variant Information for MIR718 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- MIR718
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR718 Gene
Disorders for MIR718 Gene
Additional Disease Information for MIR718
No disorders were found for MIR718 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR718 Gene
Publications for MIR718 Gene
- Involvement of microRNA-718, a new regulator of EGR3, in regulation of malignant phenotype of HCC cells. (PMID: 28070994) Wang ZD … Zhang HD (Journal of Zhejiang University. Science. B 2017) 3 58
- Predictive value of plasma miRNA-718 for esophageal squamous cell carcinoma. (PMID: 26756617) Sun L … He F (Cancer biomarkers : section A of Disease markers 2016) 3 58
- Identification of a bona fide microRNA biomarker in serum exosomes that predicts hepatocellular carcinoma recurrence after liver transplantation. (PMID: 25584485) Sugimachi K … Mimori K (British journal of cancer 2015) 3 58
- MiR-718 represses VEGF and inhibits ovarian cancer cell progression. (PMID: 24815691) Leng R … Tang L (FEBS letters 2014) 3 58
- miRNAminer: a tool for homologous microRNA gene search. (PMID: 18215311) Artzi S … Shomron N (BMC bioinformatics 2008) 3 58
Products for MIR718 Gene
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- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
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- Browse cDNA Clones
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- Cloud-Clone Corp. disease models service
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- Cloud-Clone Corp. primary cells service
- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR718
- VectorBuilder custom plasmid, inducible vectors for MIR718
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR718
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneTex for Antibodies for MIR718
- Search GeneTex for Proteins for MIR718
Sources for MIR718 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew