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Aliases for MIR711 Gene

Subcategory (RNA class) for MIR711 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR711 Gene

  • MicroRNA 711 2 3 5
  • Hsa-Mir-711 3

External Ids for MIR711 Gene

Previous GeneCards Identifiers for MIR711 Gene

  • GC00U924970
  • GC03M048616

Summaries for MIR711 Gene

Entrez Gene Summary for MIR711 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR711 Gene

MIR711 (MicroRNA 711) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Collagen chain trimerization and Transport to the Golgi and subsequent modification.

Additional gene information for MIR711 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR711 Gene

Genomics for MIR711 Gene

Genomic Locations for MIR711 Gene

Genomic Locations for MIR711 Gene
chr3:48,578,902-48,578,977
(GRCh38/hg38)
Size:
76 bases
Orientation:
Minus strand
chr3:48,616,335-48,616,410
(GRCh37/hg19)

Genomic View for MIR711 Gene

Genes around MIR711 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR711 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR711 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR711 Gene

ORGUL Member Location for MIR711 Gene

ORGUL Member Location for MIR711 gene

No data available for Regulatory Elements for MIR711 Gene

Proteins for MIR711 Gene

Post-translational modifications for MIR711 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR711 Gene

Domains & Families for MIR711 Gene

Gene Families for MIR711 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR711: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR711 Gene

Function for MIR711 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR711 Gene

Localization for MIR711 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR711 Gene

Pathways & Interactions for MIR711 Gene

genes like me logo Genes that share pathways with MIR711: view

Interacting Proteins for MIR711 Gene

Gene Ontology (GO) - Biological Process for MIR711 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008284 positive regulation of cell proliferation IMP 26998141
GO:0008285 negative regulation of cell proliferation IMP 26735582
GO:0030335 positive regulation of cell migration IMP 26998141
GO:0031658 negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle IDA 26735582
GO:0035195 gene silencing by miRNA IDA 26735582
genes like me logo Genes that share ontologies with MIR711: view

No data available for SIGNOR curated interactions for MIR711 Gene

Drugs & Compounds for MIR711 Gene

No Compound Related Data Available

Transcripts for MIR711 Gene

mRNA/cDNA for MIR711 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR711 Gene

No ASD Table

Relevant External Links for MIR711 Gene

GeneLoc Exon Structure for
MIR711
ECgene alternative splicing isoforms for
MIR711

Expression for MIR711 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR711 Gene

mRNA differential expression in normal tissues according to GTEx for MIR711 Gene

This gene is overexpressed in Skin - Not Sun Exposed (Suprapubic) (x7.8), Skin - Sun Exposed (Lower leg) (x5.6), and Prostate (x4.0).

NURSA nuclear receptor signaling pathways regulating expression of MIR711 Gene:

MIR711
genes like me logo Genes that share expression patterns with MIR711: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR711 Gene

Orthologs for MIR711 Gene

Evolution for MIR711 Gene

ENSEMBL:
Gene Tree for MIR711 (if available)
TreeFam:
Gene Tree for MIR711 (if available)

No data available for Orthologs for MIR711 Gene

Paralogs for MIR711 Gene

No data available for Paralogs for MIR711 Gene

Variants for MIR711 Gene

Sequence variations from dbSNP and Humsavar for MIR711 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs1057517723 Pathogenic 48,579,489(-) CCCCC(-/C)AGGCC nc-transcript-variant, upstream-variant-2KB, reference, frameshift-variant
rs121912841 Pathogenic 48,578,497(-) TCCGT(A/C/G)GAGAA nc-transcript-variant, downstream-variant-500B, reference, missense
rs121912845 Pathogenic 48,580,301(-) GGAGC(C/T)GGTGA nc-transcript-variant, upstream-variant-2KB, reference, missense
rs374718902 Pathogenic 48,579,241(+) CAGTC(C/G/T)GCTCC nc-transcript-variant, upstream-variant-2KB, reference, missense
rs760063197 Pathogenic 48,580,586(+) ATTTC(A/G)TCCAT nc-transcript-variant, upstream-variant-2KB, reference, stop-gained

Structural Variations from Database of Genomic Variants (DGV) for MIR711 Gene

Variant ID Type Subtype PubMed ID
nsv1004383 CNV loss 25217958
nsv3811 CNV deletion 18451855
nsv523981 CNV loss 19592680
nsv818138 CNV gain 17921354
nsv834685 CNV loss 17160897
nsv954484 CNV deletion 24416366

Relevant External Links for MIR711 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR711

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR711 Gene

Disorders for MIR711 Gene

Relevant External Links for MIR711

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR711

No disorders were found for MIR711 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR711 Gene

Publications for MIR711 Gene

  1. RASSF1A inhibits gastric cancer cell proliferation by miR-711- mediated downregulation of CDK4 expression. (PMID: 26735582) Liao A … Hu H (Oncotarget 2016) 3 60
  2. MicroRNA-711 is a prognostic factor for poor overall survival and has an oncogenic role in breast cancer. (PMID: 26998141) Hu JY … Wang HY (Oncology letters 2016) 3 60
  3. miRNAminer: a tool for homologous microRNA gene search. (PMID: 18215311) Artzi S … Shomron N (BMC bioinformatics 2008) 3 60
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR711 Gene

Sources for MIR711 Gene

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