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Aliases for MIR7-3HG Gene

Subcategory (RNA class) for MIR7-3HG Gene

miRNA

Quality Score for this RNA gene is

13

Aliases for MIR7-3HG Gene

  • MIR7-3 Host Gene 2 3 5
  • Long Intergenic Non-Protein Coding RNA 306 2 3
  • MIR7-3 Host Gene (Non-Protein Coding) 2 3
  • NCRNA00306 3 4
  • LINC00306 3 4
  • C19orf30 3 4
  • PGSF1 3 4
  • Chromosome 19 Open Reading Frame 30 2
  • Pituitary Gland Specific Factor 1a 2
  • Pituitary Gland Specific Factor 1b 2
  • Pituitary Gland Specific Factor 1 3
  • Pituitary Gland-Specific Factor 1 4
  • Non-Protein Coding RNA 306 2
  • Uc002mbe.2 3
  • Huh7 3

External Ids for MIR7-3HG Gene

Previous HGNC Symbols for MIR7-3HG Gene

  • C19orf30
  • NCRNA00306
  • LINC00306

Previous GeneCards Identifiers for MIR7-3HG Gene

  • GC19P004771
  • GC19P004773
  • GC19P004775
  • GC19P004778
  • GC19P004777
  • GC19P004779
  • GC19P004780
  • GC19P004781
  • GC19P004782
  • GC19P004783
  • GC19P004784

Summaries for MIR7-3HG Gene

GeneCards Summary for MIR7-3HG Gene

MIR7-3HG (MIR7-3 Host Gene) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR7-3HG include Gastrointestinal System Cancer.

Additional gene information for MIR7-3HG Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR7-3HG Gene

Genomics for MIR7-3HG Gene

GeneHancer (GH) Regulatory Elements for MIR7-3HG Gene

Promoters and enhancers for MIR7-3HG Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I004769 Enhancer 1.1 ENCODE 556.1 +0.6 589 0.2 FOXA2 MLX ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 IRF4 SLC30A9 MIR7-3HG GC19P004774 GC19P004786 MIR7-3 ENSG00000267030 ENSG00000267769 SAFB PTPRS CCDC94 DPP9-AS1
GH19I004770 Enhancer 0.6 ENCODE 550.8 0.0 -21 0.2 MXI1 YY2 SP2 REST ATF2 SP1 ZFHX2 POLR2A MYNN BCL6B GC19P004774 GC19P004786 MIR7-3 MIR7-3HG GC19M004737 TRV-CAC3-1
GH19I004828 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE dbSUPER 11.5 +62.1 62061 4.6 HDGF SMAD1 ARNT ARID4B SIN3A DMAP1 IRF4 YY1 SLC30A9 POLR2B TICAM1 GC19P004832 SAFB2 PLIN3 SAFB ARRDC5 FEM1A MIR7-3 MIR7-3HG SNRPEP4
GH19I004759 Enhancer 1.2 Ensembl ENCODE 12.6 -9.3 -9276 1.1 HDGF ARID4B SIN3A DMAP1 ZNF48 FOS SP5 NFYC MXD4 MIER2 MIR7-3HG ENSG00000268536 GC19M004737 TRV-CAC3-1
GH19I004744 Enhancer 1 Ensembl ENCODE 13.5 -24.0 -24008 1.1 HDAC1 FOXA2 INSM2 KLF17 ZNF366 EGR1 FOS CREM EGR2 PHF21A MIR7-3HG MIR7-3 FEM1A DPP9 PLIN3 GC19M004737 TRV-CAC3-1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR7-3HG on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR7-3HG Gene

Genomic Locations for MIR7-3HG Gene
chr19:4,769,105-4,772,556
(GRCh38/hg38)
Size:
3,452 bases
Orientation:
Plus strand
chr19:4,769,117-4,772,568
(GRCh37/hg19)

Genomic View for MIR7-3HG Gene

Genes around MIR7-3HG on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR7-3HG Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR7-3HG Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR7-3HG Gene

Proteins for MIR7-3HG Gene

  • Protein details for MIR7-3HG Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N6C7-PGSF1_HUMAN
    Recommended name:
    Putative uncharacterized protein encoded by MIR7-3HG
    Protein Accession:
    Q8N6C7
    Secondary Accessions:
    • D6W630
    • Q17RJ9
    • Q8N6C6

    Protein attributes for MIR7-3HG Gene

    Size:
    128 amino acids
    Molecular mass:
    14321 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for MIR7-3HG Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for MIR7-3HG Gene

Post-translational modifications for MIR7-3HG Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR7-3HG Gene

Domains & Families for MIR7-3HG Gene

Protein Domains for MIR7-3HG Gene

ProtoNet:

Suggested Antigen Peptide Sequences for MIR7-3HG Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR7-3HG: view

No data available for Gene Families and UniProtKB/Swiss-Prot for MIR7-3HG Gene

Function for MIR7-3HG Gene

Phenotypes From GWAS Catalog for MIR7-3HG Gene

Phenotypes for MIR7-3HG Gene

GenomeRNAi human phenotypes for MIR7-3HG:
genes like me logo Genes that share phenotypes with MIR7-3HG: view

miRNA for MIR7-3HG Gene

miRTarBase miRNAs that target MIR7-3HG

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MIR7-3HG Gene

Localization for MIR7-3HG Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR7-3HG Gene

Pathways & Interactions for MIR7-3HG Gene

SuperPathways for MIR7-3HG Gene

No Data Available

Interacting Proteins for MIR7-3HG Gene

Gene Ontology (GO) - Biological Process for MIR7-3HG Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR7-3HG Gene

Drugs & Compounds for MIR7-3HG Gene

No Compound Related Data Available

Transcripts for MIR7-3HG Gene

Unigene Clusters for MIR7-3HG Gene

MIR7-3 host gene (non-protein coding):
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR7-3HG Gene

No ASD Table

Relevant External Links for MIR7-3HG Gene

GeneLoc Exon Structure for
MIR7-3HG
ECgene alternative splicing isoforms for
MIR7-3HG

Expression for MIR7-3HG Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR7-3HG Gene

mRNA differential expression in normal tissues according to GTEx for MIR7-3HG Gene

This gene is overexpressed in Pituitary (x48.2).

SOURCE GeneReport for Unigene cluster for MIR7-3HG Gene:

Hs.326728

mRNA Expression by UniProt/SwissProt for MIR7-3HG Gene:

Q8N6C7-PGSF1_HUMAN
Tissue specificity: High expression in pituitary gland and weak in pancreas.

Evidence on tissue expression from TISSUES for MIR7-3HG Gene

  • Liver(3.5)
genes like me logo Genes that share expression patterns with MIR7-3HG: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR7-3HG Gene

Orthologs for MIR7-3HG Gene

Evolution for MIR7-3HG Gene

ENSEMBL:
Gene Tree for MIR7-3HG (if available)
TreeFam:
Gene Tree for MIR7-3HG (if available)

No data available for Orthologs for MIR7-3HG Gene

Paralogs for MIR7-3HG Gene

No data available for Paralogs for MIR7-3HG Gene

Variants for MIR7-3HG Gene

Sequence variations from dbSNP and Humsavar for MIR7-3HG Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000538097 -- 4,771,641(+) T/C intron_variant
rs1000914634 -- 4,767,509(+) C/T upstream_transcript_variant
rs1001444042 -- 4,768,952(+) C/T upstream_transcript_variant
rs1001647487 -- 4,773,036(+) G/C downstream_transcript_variant
rs1001791878 -- 4,769,179(+) A/G non_coding_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR7-3HG Gene

Variant ID Type Subtype PubMed ID
nsv1062709 CNV loss 25217958
nsv578452 CNV loss 21841781

Additional Variant Information for MIR7-3HG Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR7-3HG

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR7-3HG Gene

Disorders for MIR7-3HG Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR7-3HG Gene - From: DISEASES

Disorder Aliases PubMed IDs
gastrointestinal system cancer
  • digestive system cancer
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR7-3HG

genes like me logo Genes that share disorders with MIR7-3HG: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR7-3HG Gene

Publications for MIR7-3HG Gene

  1. Expression profile of active genes in the human pituitary gland. (PMID: 11854097) Tanaka S … Amino N (Journal of molecular endocrinology 2002) 2 3 4 22 58
  2. Induction of the liver cancer-down-regulated long noncoding RNA uc002mbe.2 mediates trichostatin-induced apoptosis of liver cancer cells. (PMID: 23643933) Yang H … Wan YJ (Biochemical pharmacology 2013) 2 3 58
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  4. MIR7-3HG, a MYC-dependent modulator of cell proliferation, inhibits autophagy by a regulatory loop involving AMBRA1. (PMID: 28059583) Capizzi M … Cecconi F (Autophagy 2017) 3 58
  5. MicroRNA-7 downregulates the oncogene VDAC1 to influence hepatocellular carcinoma proliferation and metastasis. (PMID: 26831666) Wang F … Chen Z (Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016) 3 58

Products for MIR7-3HG Gene

Sources for MIR7-3HG Gene

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