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Aliases for MIR7-3HG Gene

Subcategory (RNA class) for MIR7-3HG Gene

miRNA

Quality Score for this RNA gene is

13

Aliases for MIR7-3HG Gene

  • MIR7-3 Host Gene 2 3 5
  • Long Intergenic Non-Protein Coding RNA 306 2 3
  • MIR7-3 Host Gene (Non-Protein Coding) 2 3
  • NCRNA00306 3 4
  • LINC00306 3 4
  • C19orf30 3 4
  • PGSF1 3 4
  • Chromosome 19 Open Reading Frame 30 2
  • Pituitary Gland Specific Factor 1a 2
  • Pituitary Gland Specific Factor 1b 2
  • Pituitary Gland Specific Factor 1 3
  • Pituitary Gland-Specific Factor 1 4
  • Non-Protein Coding RNA 306 2
  • Uc002mbe.2 3
  • Huh7 3

External Ids for MIR7-3HG Gene

Previous HGNC Symbols for MIR7-3HG Gene

  • C19orf30
  • NCRNA00306
  • LINC00306

Previous GeneCards Identifiers for MIR7-3HG Gene

  • GC19P004771
  • GC19P004773
  • GC19P004775
  • GC19P004778
  • GC19P004777
  • GC19P004779
  • GC19P004780
  • GC19P004781
  • GC19P004782

Summaries for MIR7-3HG Gene

GeneCards Summary for MIR7-3HG Gene

MIR7-3HG (MIR7-3 Host Gene) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR7-3HG include Gastrointestinal System Cancer.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR7-3HG Gene

Genomics for MIR7-3HG Gene

Regulatory Elements for MIR7-3HG Gene

Enhancers for MIR7-3HG Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19G004759 1.3 Ensembl ENCODE 12.6 -9.3 -9276 1.1 HDGF ARID4B DMAP1 ZNF48 ZNF143 FOS ZNF263 SP5 NFYC MXD4 MIR7-3HG ENSG00000268536 GC19M004737 TRV-CAC3-1
GH19G004828 1.3 ENCODE dbSUPER 11.5 +62.1 62062 4.6 HDGF ARNT SIN3A ARID4B DMAP1 YY1 SLC30A9 ZNF143 ZNF207 ZNF548 SAFB2 PLIN3 SAFB ARRDC5 FEM1A MIR7-3 MIR7-3HG SNRPEP4 ENSG00000269807 DPP9-AS1
GH19G004744 1.1 Ensembl ENCODE 13.5 -24.0 -24008 1.1 FOXA2 SIN3A INSM2 KLF17 EGR1 ZNF366 ZMIZ1 FOS CREM EGR2 MIR7-3HG MIR7-3 FEM1A DPP9 PLIN3 GC19M004737 TRV-CAC3-1
GH19G004741 0.7 ENCODE 13.5 -26.4 -26391 1.4 MXI1 ZNF473 ZSCAN4 CEBPG ZIC2 ZNF48 RAD21 ZFHX2 ZBTB48 SMC3 MIR7-3 MIR7-3HG FEM1A PLIN3 TRV-CAC3-1 GC19M004737
GH19G004769 1.1 ENCODE 6 +0.6 589 0.2 FOXA2 CREB3L1 MLX ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 SLC30A9 SAFB2 HDGFL2 SAFB ENSG00000267980 MIR7-3HG GC19P004784
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR7-3HG on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR7-3HG Gene

Chromosome:
19
Start:
4,769,105 bp from pter
End:
4,772,556 bp from pter
Size:
3,452 bases
Orientation:
Plus strand

Genomic View for MIR7-3HG Gene

Genes around MIR7-3HG on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR7-3HG Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR7-3HG Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR7-3HG Gene

Proteins for MIR7-3HG Gene

  • Protein details for MIR7-3HG Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N6C7-PGSF1_HUMAN
    Recommended name:
    Putative uncharacterized protein encoded by MIR7-3HG
    Protein Accession:
    Q8N6C7
    Secondary Accessions:
    • D6W630
    • Q17RJ9
    • Q8N6C6

    Protein attributes for MIR7-3HG Gene

    Size:
    128 amino acids
    Molecular mass:
    14321 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for MIR7-3HG Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for MIR7-3HG Gene

Post-translational modifications for MIR7-3HG Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR7-3HG Gene

Domains & Families for MIR7-3HG Gene

Protein Domains for MIR7-3HG Gene

ProtoNet:

Suggested Antigen Peptide Sequences for MIR7-3HG Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR7-3HG: view

No data available for Gene Families and UniProtKB/Swiss-Prot for MIR7-3HG Gene

Function for MIR7-3HG Gene

Phenotypes for MIR7-3HG Gene

GenomeRNAi human phenotypes for MIR7-3HG:
genes like me logo Genes that share phenotypes with MIR7-3HG: view

Animal Model Products

miRNA for MIR7-3HG Gene

miRTarBase miRNAs that target MIR7-3HG

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MIR7-3HG Gene

Localization for MIR7-3HG Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR7-3HG Gene

Pathways & Interactions for MIR7-3HG Gene

SuperPathways for MIR7-3HG Gene

No Data Available

Interacting Proteins for MIR7-3HG Gene

Gene Ontology (GO) - Biological Process for MIR7-3HG Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR7-3HG Gene

Transcripts for MIR7-3HG Gene

Unigene Clusters for MIR7-3HG Gene

MIR7-3 host gene (non-protein coding):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for MIR7-3HG Gene

No ASD Table

Relevant External Links for MIR7-3HG Gene

GeneLoc Exon Structure for
MIR7-3HG
ECgene alternative splicing isoforms for
MIR7-3HG

Expression for MIR7-3HG Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR7-3HG Gene

mRNA differential expression in normal tissues according to GTEx for MIR7-3HG Gene

This gene is overexpressed in Pituitary (x48.2).

SOURCE GeneReport for Unigene cluster for MIR7-3HG Gene:

Hs.326728

mRNA Expression by UniProt/SwissProt for MIR7-3HG Gene:

Q8N6C7-PGSF1_HUMAN
Tissue specificity: High expression in pituitary gland and weak in pancreas.

Evidence on tissue expression from TISSUES for MIR7-3HG Gene

  • Liver(3.5)
genes like me logo Genes that share expression patterns with MIR7-3HG: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR7-3HG Gene

Orthologs for MIR7-3HG Gene

Evolution for MIR7-3HG Gene

ENSEMBL:
Gene Tree for MIR7-3HG (if available)
TreeFam:
Gene Tree for MIR7-3HG (if available)

No data available for Orthologs for MIR7-3HG Gene

Paralogs for MIR7-3HG Gene

No data available for Paralogs for MIR7-3HG Gene

Variants for MIR7-3HG Gene

Sequence variations from dbSNP and Humsavar for MIR7-3HG Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1000538097 -- 4,771,641(+) CAATA(C/T)AGTGA intron-variant
rs1000914634 -- 4,767,509(+) TTTGT(C/T)CTGGC upstream-variant-2KB
rs1001444042 -- 4,768,952(+) CTAGC(C/T)CAGTT upstream-variant-2KB
rs1001647487 -- 4,773,036(+) GAGGA(C/G)GACAT downstream-variant-500B
rs1001791878 -- 4,769,179(+) GGCAC(A/G)CAGAG nc-transcript-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR7-3HG Gene

Variant ID Type Subtype PubMed ID
nsv1062709 CNV loss 25217958
nsv578452 CNV loss 21841781

Relevant External Links for MIR7-3HG Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR7-3HG

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR7-3HG Gene

Disorders for MIR7-3HG Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR7-3HG Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
gastrointestinal system cancer
  • digestive system cancer
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for MIR7-3HG

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR7-3HG
genes like me logo Genes that share disorders with MIR7-3HG: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR7-3HG Gene

Publications for MIR7-3HG Gene

  1. Expression profile of active genes in the human pituitary gland. (PMID: 11854097) Tanaka S. … Amino N. (J. Mol. Endocrinol. 2002) 2 3 4 22 64
  2. Induction of the liver cancer-down-regulated long noncoding RNA uc002mbe.2 mediates trichostatin-induced apoptosis of liver cancer cells. (PMID: 23643933) Yang H. … Wan Y.J. (Biochem. Pharmacol. 2013) 2 3 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  4. MicroRNA-7 downregulates the oncogene VDAC1 to influence hepatocellular carcinoma proliferation and metastasis. (PMID: 26831666) Wang F. … Chen Z. (Tumour Biol. 2016) 3 64
  5. Inhibition of miR-7 promotes angiogenesis in human umbilical vein endothelial cells by upregulating VEGF via KLF4. (PMID: 27431648) Li Y.Z. … Liu W.C. (Oncol. Rep. 2016) 3 64

Products for MIR7-3HG Gene

Sources for MIR7-3HG Gene

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