MIR7-3HG Gene
RNA gene GIFtS : 32
GCID: GC19 P004773
MIR7-3 host gene (non-protein coding) (Previous names: chromosome 19 open reading frame 30, non-protein coding... ) (Previous symbols: C19orf30, NCRNA00306, LINC00306 )
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Aliasesfor MIR7-3HG gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Subcategory (RNA class): lncRNAQuality score for this RNA gene is 3 Aliases MIR7-3 Host Gene (Non-Protein Coding) 1 2 PGSF1b1 C19orf301 2 3 Chromosome 19 Open Reading Frame 301 LINC003061 2 3 Long Intergenic Non-Protein Coding RNA 3061 NCRNA003061 2 3 Non-Protein Coding RNA 3061 PGSF11 2 3 Pituitary Gland-Specific Factor 13 PGSF1a1
External Ids: HGNC: 30049 1 Entrez Gene: 284424 2 Ensembl: ENSG00000176840 7 UniProtKB: Q8N6C7 3 ORGUL members: NONCODE:n407680
Export aliases for MIR7-3HG gene to outside databases Previous GC identifer: GC19P004771
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Summariesfor MIR7-3HG gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section --
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Genomic Viewsfor MIR7-3HG gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000019.9 NC_018930.1 NT_011255.14 Regulatory elements: Search SABiosciences Regulatory transcription factor binding sites for MIR7-3HG Other transcription factors Search SABiosciences Chromatin IP Primers for MIR7-3HG Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MIR7-3HG
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 19p13.3 Ensembl cytogenetic band: 19p13.3 HGNC cytogenetic band: 19p13.3 MIR7-3HG Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 19 GeneLoc Exon Structure
GeneLoc location for GC19P004773: view genomic region
(about GC identifiers )
Start:
4,769,117 bp from pter
End:
4,772,568 bp from pter
Size:
3,452 bases
Orientation:
plus strand
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Proteinsfor MIR7-3HG gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: PGSF1_HUMAN, Q8N6C7 (See
protein sequence )Recommended Name: Putative uncharacterized protein encoded by MIR7-3HG Size : 128 amino acids; 14321 Da
Caution : Product of a dubious CDS prediction. May be a non-coding RNA
Secondary accessions : D6W630 Q17RJ9 Q8N6C6Alternative splicing : 2 isoforms : Q8N6C7-1 Q8N6C7-2 (May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay)Explore the universe of human proteins at neXtProt for MIR7-3HG: NX_Q8N6C7 MIR7-3HG Protein expression data from MOPED and PaxDb : --
ENSEMBL proteins: ENSP00000465983 ENSP00000465856 ENSP00000468311 ENSP00000467440 ENSP00000465836 ENSP00000467289 ENSP00000467689 ENSP00000465179 Human Recombinant Protein Products for MIR7-3HG: MIR7-3HG Antibody Products: Assay Products for MIR7-3HG:
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Protein
Domains / Familiesfor MIR7-3HG gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section ProtoNet protein and cluster: Q8N6C7
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Functionfor MIR7-3HG gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
Sirion Biotech ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Sirion Biotech ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
Sirion Biotech ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Phenotypes: 1 GenomeRNAi human phenotype for MIR7-3HG :Animal Models: In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MIR7-3HG
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Pathways & Interactionsfor MIR7-3HG gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MIR7-3HG
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Drugs & Compoundsfor MIR7-3HG gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for MIR7-3HG Search CenterWatch for drugs/clinical trials and news about MIR7-3HG
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Transcriptsfor MIR7-3HG gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
Sirion Biotech ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for MIR7-3HG gene: NM_174947.2 Unigene Cluster for MIR7-3HG:
MIR7-3 host gene (non-protein coding) Hs.326728 [show with all ESTs ] Unigene Representative Sequence: BE779752 11 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000317292 (uc002mbd.3 uc002mbe.3 uc010xii.2 ) ENST00000586721 ENST00000592709 ENST00000588711 ENST00000589639 ENST00000591008 ENST00000592663 ENST00000588758 ENST00000588923 ENST00000589368 ENST00000540211 Additional cDNA sequence: AB058892.2 BC090884.1 BC117294.1 BC117296.1 BC143983.1 NR_027148.1
5 DOTS entries : DT.75101919 DT.100779671
DT.99976914 DT.121487798 DT.91736370 24/44 AceView cDNA sequences (see all 44 ):
AI281968 AI703043 BE550197 AA977000 AW135146 BE220327 AI733168 AW205881 AI288709 AA976576 BE503154 AB058893 BX096907 AI700564 AB058892 NM_174947 BE467100 AA988634 CD106009 BE671262 CD109008 CD251059 AI498273 CD513358 GeneLoc Exon Structure 5/7 Alternative Splicing Database (ASD) splice patterns (SP) for MIR7-3HG (see all 7 ) About this scheme ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b · 6c · 6d · 6e SP1 :       -   -                 -           SP2 :       -       -         -   -   -           SP3 :       -                             SP4 :                     -     -           SP5 :       -       -   -   -   -   -   -   -          
ECgene alternative splicing isoforms for MIR7-3HG
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Expression for MIR7-3HG gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section Expression evidence for MIR7-3HG:none
MIR7-3HG expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: TGTTGAATCAAbout this image Genevestigator expression for MIR7-3HG SOURCE GeneReport for Unigene cluster: Hs.326728
UniProtKB/Swiss-Prot: PGSF1_HUMAN, Q8N6C7 Tissue specificity : High expression in pituitary gland and weak in pancreas SABiosciences Custom PCR Arrays for MIR7-3HG Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for MIR7-3HGBrowse OriGene validated miRNA SYBR primer pairs Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat MIR7-3HG QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat MIR7-3HG QIAGEN QuantiFast Probe-based Assays in human , mouse , rat MIR7-3HG In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MIR7-3HG
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Orthologsfor MIR7-3HG gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
--
ENSEMBL Gene Tree for MIR7-3HG (if available)TreeFam Gene Tree for MIR7-3HG (if available)
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Paralogsfor MIR7-3HG gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section --
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Genomic Variantsfor MIR7-3HG gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 19 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for MIR7-3HG (4769117 - 4772568 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for MIR7-3HG: --
SABiosciences Cancer Mutation PCR Assays
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Disorders
/ Diseasesfor MIR7-3HG gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
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Publicationsfor MIR7-3HG gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for MIR7-3HG gene integrated from 9 sources : (articles sorted by number of sources associating them with MIR7-3HG) Utopia : connect your pdf to the dynamic world of online information
Expression profile of active genes in the human pituitary gland. (PubMed id 11854097) 1 , 2 , 3, 9 Tanaka S....Amino N. (2002) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 1 , 2 Gerhard D.S....Malek J. (2004) Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560) 1 Kimura K.... Sugano S. (2006) The DNA sequence and biology of human chromosome 19. (PubMed id 15057824) 2 Grimwood J.... Lucas S.M. (2004) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932) 1 Strausberg R.L....Marra M.A. (2002) Maternal zinc deficiency raises plasma prolactin levels in lactating rats. (PubMed id 15173390) 9 Chowanadisai W....Lonnerdal B. (2004)
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External Searches for MIR7-3HG gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing MIR7-3HG gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing MIR7-3HG gene
(According to HUGE )
About This Section --
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Specialized Databases showing MIR7-3HG gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for MIR7-3HG Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for MIR7-3HG gene: Search GeneIP for patents involving MIR7-3HG GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor MIR7-3HG gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 and Sirion Biotech , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , LifeMap BioReagents , and Sirion Biotech , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory )About This Section
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MIR7-3HG Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MIR7-3HG QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MIR7-3HG QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat MIR7-3HG QIAGEN QuantiFast Probe-based Assays in human , mouse , rat MIR7-3HG QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat MIR7-3HG
MIR7-3HG Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MIR7-3HG
Search ThermoFisher Antibodies for MIR7-3HG
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat MIR7-3HG
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