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Aliases for MIR7-3 Gene

Subcategory (RNA class) for MIR7-3 Gene


Quality Score for this RNA gene is


Aliases for MIR7-3 Gene

  • MicroRNA 7-3 2 3 5
  • Hsa-Mir-7-3 3
  • MiR-7-5p 3
  • Mir-7-3 3
  • MIRN7-3 3

External Ids for MIR7-3 Gene

ORGUL Members for MIR7-3 Gene

Previous HGNC Symbols for MIR7-3 Gene

  • MIRN7-3

Previous GeneCards Identifiers for MIR7-3 Gene

  • GC19P004726

Summaries for MIR7-3 Gene

Entrez Gene Summary for MIR7-3 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR7-3 Gene

MIR7-3 (MicroRNA 7-3) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR7-3 Gene

Genomics for MIR7-3 Gene

Regulatory Elements for MIR7-3 Gene

Enhancers for MIR7-3 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19F004744 1 Ensembl ENCODE 13.4 -25.6 -25573 1.1 INSM2 KLF17 SIN3A ZNF366 FOS ZMIZ1 CREM EGR2 REST ZEB2 MIR7-3HG MIR7-3 FEM1A DPP9 PLIN3 TRV-CAC3-1 GC19M004737
GH19F004741 0.2 ENCODE 13.4 -28.0 -27956 1.4 ZBTB10 MAZ REST CEBPG MNT ZIC2 ZNF48 PRDM2 ZFHX2 ZBTB48 MIR7-3 MIR7-3HG FEM1A PLIN3 GC19M004737 TRV-CAC3-1
GH19F004828 0.2 ENCODE 11.5 +60.5 60497 4.6 HDGF ARNT ARID4B SIN3A DMAP1 YY1 SLC30A9 ZNF143 ZNF207 ZNF548 SAFB2 PLIN3 SAFB ARRDC5 FEM1A MIR7-3 MIR7-3HG SNRPEP4 ENSG00000269807 DPP9-AS1
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR7-3 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR7-3 Gene

4,770,670 bp from pter
4,770,779 bp from pter
110 bases
Plus strand

Genomic View for MIR7-3 Gene

Genes around MIR7-3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR7-3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR7-3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR7-3 Gene

Proteins for MIR7-3 Gene

Post-translational modifications for MIR7-3 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR7-3 Gene

Domains & Families for MIR7-3 Gene

Gene Families for MIR7-3 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR7-3: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR7-3 Gene

Function for MIR7-3 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR7-3 Gene

Localization for MIR7-3 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR7-3 Gene

Pathways & Interactions for MIR7-3 Gene

SuperPathways for MIR7-3 Gene

SuperPathway Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR7-3: view

Pathways by source for MIR7-3 Gene

1 KEGG pathway for MIR7-3 Gene

Interacting Proteins for MIR7-3 Gene

Gene Ontology (GO) - Biological Process for MIR7-3 Gene


No data available for SIGNOR curated interactions for MIR7-3 Gene

Transcripts for MIR7-3 Gene

mRNA/cDNA for MIR7-3 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR7-3 Gene

No ASD Table

Relevant External Links for MIR7-3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR7-3 Gene

mRNA expression in normal human tissues for MIR7-3 Gene

genes like me logo Genes that share expression patterns with MIR7-3: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR7-3 Gene

Orthologs for MIR7-3 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR7-3 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ptr-mir-7-3 35
  • 100 (a)
(Canis familiaris)
Mammalia cfa-mir-7-3 35
  • 84 (a)
(Mus musculus)
Mammalia Mir7b 35
  • 73 (a)
(Bos Taurus)
Mammalia bta-mir-7-3 35
  • 70 (a)
(Monodelphis domestica)
Mammalia -- 35
  • 68 (a)
(Gallus gallus)
Aves gga-mir-7-3 35
  • 76 (a)
(Danio rerio)
Actinopterygii CR933818.1 35
  • 63 (a)
sea squirt
(Ciona savignyi)
Ascidiacea csa-mir-7 35
  • 51 (a)
Species where no ortholog for MIR7-3 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR7-3 Gene

Gene Tree for MIR7-3 (if available)
Gene Tree for MIR7-3 (if available)

Paralogs for MIR7-3 Gene

No data available for Paralogs for MIR7-3 Gene

Variants for MIR7-3 Gene

Sequence variations from dbSNP and Humsavar for MIR7-3 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs112767210 -- 4,770,037(+) ATCTG(C/G)GATTA intron-variant, upstream-variant-2KB
rs113847618 -- 4,769,550(+) CGGGG(-/A)AAAGA intron-variant, upstream-variant-2KB
rs114054957 -- 4,770,911(+) AAGGA(C/T)ATACA intron-variant, downstream-variant-500B
rs114145113 -- 4,769,743(+) ACCCT(C/G)GACAG nc-transcript-variant, upstream-variant-2KB
rs116475299 -- 4,771,069(+) TGACA(C/T)TTAAA intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR7-3 Gene

Variant ID Type Subtype PubMed ID
nsv1062709 CNV loss 25217958
nsv578452 CNV loss 21841781

Relevant External Links for MIR7-3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR7-3 Gene

Disorders for MIR7-3 Gene

Relevant External Links for MIR7-3

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR7-3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR7-3 Gene

Publications for MIR7-3 Gene

  1. miR-7-5p suppresses cell proliferation and induces apoptosis of breast cancer cells mainly by targeting REGI^. (PMID: 25511742) Shi Y. … Ren G. (Cancer Lett. 2015) 3 64
  2. MicroRNA-7 Promotes Glycolysis to Protect against 1-Methyl-4-phenylpyridinium-induced Cell Death. (PMID: 25814668) Chaudhuri A.D. … Junn E. (J. Biol. Chem. 2015) 3 64
  3. miR-7 modulates chemoresistance of small cell lung cancer by repressing MRP1/ABCC1. (PMID: 26108539) Liu H. … Guo L. (Int J Exp Pathol 2015) 3 64
  4. MicroRNA-7 inhibits the stemness of prostate cancer stem-like cells and tumorigenesis by repressing KLF4/PI3K/Akt/p21 pathway. (PMID: 26172296) Chang Y.L. … Gao W.Q. (Oncotarget 2015) 3 64
  5. MicroRNA-7 activates Nrf2 pathway by targeting Keap1 expression. (PMID: 26453926) Kabaria S. … Junn E. (Free Radic. Biol. Med. 2015) 3 64

Products for MIR7-3 Gene

Sources for MIR7-3 Gene

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