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Aliases for MIR7-2 Gene

Subcategory (RNA class) for MIR7-2 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR7-2 Gene

  • MicroRNA 7-2 2 3 5
  • Hsa-Mir-7-2 3
  • MiR-7-5p 3
  • Mir-7-2 3
  • MIRN7-2 3

External Ids for MIR7-2 Gene

ORGUL Members for MIR7-2 Gene

Previous HGNC Symbols for MIR7-2 Gene

  • MIRN7-2

Previous GeneCards Identifiers for MIR7-2 Gene

  • GC15P086959
  • GC15P089155

Summaries for MIR7-2 Gene

Entrez Gene Summary for MIR7-2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR7-2 Gene

MIR7-2 (MicroRNA 7-2) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR7-2 Gene

Genomics for MIR7-2 Gene

Genomic Location for MIR7-2 Gene

Chromosome:
15
Start:
88,611,825 bp from pter
End:
88,611,934 bp from pter
Size:
110 bases
Orientation:
Plus strand

Genomic View for MIR7-2 Gene

Genes around MIR7-2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR7-2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR7-2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR7-2 Gene

No data available for Regulatory Elements for MIR7-2 Gene

Proteins for MIR7-2 Gene

Post-translational modifications for MIR7-2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR7-2 Gene

Domains & Families for MIR7-2 Gene

Gene Families for MIR7-2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR7-2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR7-2 Gene

Function for MIR7-2 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR7-2 Gene

Localization for MIR7-2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR7-2 Gene

Pathways & Interactions for MIR7-2 Gene

SuperPathways for MIR7-2 Gene

Superpath Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR7-2: view

Pathways by source for MIR7-2 Gene

1 KEGG pathway for MIR7-2 Gene

Interacting Proteins for MIR7-2 Gene

Gene Ontology (GO) - Biological Process for MIR7-2 Gene

None

No data available for SIGNOR curated interactions for MIR7-2 Gene

Drugs & Compounds for MIR7-2 Gene

No Compound Related Data Available

Transcripts for MIR7-2 Gene

mRNA/cDNA for MIR7-2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR7-2 Gene

No ASD Table

Relevant External Links for MIR7-2 Gene

GeneLoc Exon Structure for
MIR7-2
ECgene alternative splicing isoforms for
MIR7-2

Expression for MIR7-2 Gene

mRNA expression in normal human tissues for MIR7-2 Gene

genes like me logo Genes that share expression patterns with MIR7-2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR7-2 Gene

Orthologs for MIR7-2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR7-2 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia bta-mir-7-1 36
  • 84 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 68 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir7-2 36
  • 77 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-7-2 36
  • 63 (a)
OneToMany
oan-mir-7-3 36
  • 80 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-7-2 36
  • 99 (a)
OneToOne
chicken
(Gallus gallus)
Aves gga-mir-7-2 36
  • 71 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-7-3 36
  • 59 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dre-mir-7a-1 36
  • 65 (a)
OneToMany
dre-mir-7a-2 36
  • 53 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea csa-mir-7 36
  • 51 (a)
OneToMany
Species with no ortholog for MIR7-2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR7-2 Gene

ENSEMBL:
Gene Tree for MIR7-2 (if available)
TreeFam:
Gene Tree for MIR7-2 (if available)

Paralogs for MIR7-2 Gene

No data available for Paralogs for MIR7-2 Gene

Variants for MIR7-2 Gene

Relevant External Links for MIR7-2 Gene

HapMap Linkage Disequilibrium report
MIR7-2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR7-2 Gene

Disorders for MIR7-2 Gene

Relevant External Links for MIR7-2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR7-2

No disorders were found for MIR7-2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR7-2 Gene

Publications for MIR7-2 Gene

  1. MicroRNA-7 Promotes Glycolysis to Protect against 1-Methyl-4-phenylpyridinium-induced Cell Death. (PMID: 25814668) Chaudhuri A.D. … Junn E. (J. Biol. Chem. 2015) 3 67
  2. miR-7-5p suppresses cell proliferation and induces apoptosis of breast cancer cells mainly by targeting REGI^. (PMID: 25511742) Shi Y. … Ren G. (Cancer Lett. 2015) 3
  3. miR-7 modulates chemoresistance of small cell lung cancer by repressing MRP1/ABCC1. (PMID: 26108539) Liu H. … Guo L. (Int J Exp Pathol 2015) 3
  4. miR-7 inhibits the invasion and metastasis of gastric cancer cells by suppressing epidermal growth factor receptor expression. (PMID: 24573489) Xie J. … Li G.Q. (Oncol. Rep. 2014) 3
  5. miR-7 inhibits glioblastoma growth by simultaneously interfering with the PI3K/ATK and Raf/MEK/ERK pathways. (PMID: 24603851) Liu Z. … Liu X. (Int. J. Oncol. 2014) 3

Products for MIR7-2 Gene

Sources for MIR7-2 Gene

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