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Aliases for MIR7-1 Gene

Subcategory (RNA class) for MIR7-1 Gene


Quality Score for this RNA gene is


Aliases for MIR7-1 Gene

  • MicroRNA 7-1 2 3 5
  • Hsa-Mir-7-1 3
  • MiR-7-5p 3
  • Mir-7-1 3
  • MIRN7-1 3

External Ids for MIR7-1 Gene

Previous HGNC Symbols for MIR7-1 Gene

  • MIRN7-1

Previous GeneCards Identifiers for MIR7-1 Gene

  • GC09M085776
  • GC09M086584

Summaries for MIR7-1 Gene

Entrez Gene Summary for MIR7-1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR7-1 Gene

MIR7-1 (MicroRNA 7-1) is an RNA Gene, and is affiliated with the undefined RNA class. Among its related pathways are mRNA Splicing - Major Pathway and SUMOylation.

fRNAdb sequence ontologies for MIR7-1 Gene

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

View fRNAdb secondary structures for MIR7-1

Additional gene information for MIR7-1 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR7-1 Gene

Genomics for MIR7-1 Gene

Regulatory Elements for MIR7-1 Gene

Enhancers for MIR7-1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09H083965 1 Ensembl ENCODE 0.7 +4.3 4269 1.2 HDAC1 PKNOX1 RB1 CEBPG ZNF324 CTBP1 POLR2A ZNF600 ATF7 PAF1 KIF27 LOC105376116 IDNK ENSG00000231616 MIR7-1 C9orf64
GH09H083961 0.9 ENCODE 0.4 +7.4 7375 1.3 TBP INSM2 FEZF1 YY1 KLF7 ZNF362 CEBPB ELF1 ZEB2 ZNF518A KIF27 LOC105376116 RMI1 MIR7-1 C9orf64
GH09H083959 0.6 ENCODE 0.4 +10.6 10627 0.2 ZNF384 TEAD3 JUND MAFF ZNF629 PRDM10 WT1 ZXDB C9orf64 MIR7-1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR7-1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR7-1 Gene

Genomic Locations for MIR7-1 Gene
110 bases
Minus strand

Genomic View for MIR7-1 Gene

Genes around MIR7-1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR7-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR7-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR7-1 Gene

ORGUL Member Location for MIR7-1 Gene

ORGUL Member Location for MIR7-1 gene

Proteins for MIR7-1 Gene

Post-translational modifications for MIR7-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR7-1 Gene

Domains & Families for MIR7-1 Gene

Gene Families for MIR7-1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR7-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR7-1 Gene

Function for MIR7-1 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR7-1 Gene

Localization for MIR7-1 Gene

Gene Ontology (GO) - Cellular Components for MIR7-1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 18766170
genes like me logo Genes that share ontologies with MIR7-1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR7-1 Gene

Pathways & Interactions for MIR7-1 Gene

genes like me logo Genes that share pathways with MIR7-1: view

Pathways by source for MIR7-1 Gene

1 KEGG pathway for MIR7-1 Gene

Interacting Proteins for MIR7-1 Gene

Gene Ontology (GO) - Biological Process for MIR7-1 Gene


No data available for SIGNOR curated interactions for MIR7-1 Gene

Drugs & Compounds for MIR7-1 Gene

No Compound Related Data Available

Transcripts for MIR7-1 Gene

fRNAdb Secondary structures for MIR7-1 Gene

  • FR244379

mRNA/cDNA for MIR7-1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR7-1 Gene

No ASD Table

Relevant External Links for MIR7-1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR7-1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR7-1 Gene

genes like me logo Genes that share expression patterns with MIR7-1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR7-1 Gene

Orthologs for MIR7-1 Gene

Evolution for MIR7-1 Gene

Gene Tree for MIR7-1 (if available)
Gene Tree for MIR7-1 (if available)

No data available for Orthologs for MIR7-1 Gene

Paralogs for MIR7-1 Gene

No data available for Paralogs for MIR7-1 Gene

Variants for MIR7-1 Gene

Sequence variations from dbSNP and Humsavar for MIR7-1 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs767454980 Pathogenic 83,970,273(+) CTCCC(A/G/T)ACTCA upstream-variant-2KB, reference, missense, stop-gained
rs1002519950 -- 83,969,629(+) TAAAT(C/T)GGACA intron-variant, downstream-variant-500B
rs1003514753 -- 83,969,638(+) CATTA(A/G)TAGAA intron-variant, downstream-variant-500B
rs1006188137 -- 83,970,973(+) TACTT(A/T)AAAAA intron-variant, upstream-variant-2KB
rs1006460187 -- 83,971,517(+) AATCC(C/T)CCAGC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR7-1 Gene

Variant ID Type Subtype PubMed ID
nsv972408 CNV duplication 23825009
nsv8541 CNV gain 18304495
nsv831644 CNV gain 17160897
nsv469859 CNV gain 16826518
nsv436717 OTHER inversion 17901297
nsv1043703 CNV gain 25217958
esv3620911 CNV gain 21293372
esv2759701 CNV gain 17122850

Relevant External Links for MIR7-1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR7-1 Gene

Disorders for MIR7-1 Gene

Relevant External Links for MIR7-1

Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR7-1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR7-1 Gene

Publications for MIR7-1 Gene

  1. TWEAK-stimulated macrophages inhibit metastasis of epithelial ovarian cancer via exosomal shuttling of microRNA. (PMID: 28216373) Hu Y … Qiu L (Cancer letters 2017) 3 60
  2. Breviscapine suppresses the growth of non-small cell lung cancer by enhancing microRNA-7 expression. (PMID: 28229971) Zeng J … Cai S (Journal of biosciences 2017) 3 60
  3. Significance and Function of MicroRNA-7 in Oesophageal Squamous Cell Carcinoma. (PMID: 28314263) Hara K … Kuwano H (Anticancer research 2017) 3 60
  4. microRNA-7 impairs autophagy-derived pools of glucose to suppress pancreatic cancer progression. (PMID: 28450156) Gu DN … Tian L (Cancer letters 2017) 3 60
  5. Role of microRNA-7 and selenoprotein P in hepatocellular carcinoma. (PMID: 28459371) Tarek M … Montasser IF (Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017) 3 60

Products for MIR7-1 Gene

Sources for MIR7-1 Gene

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