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Aliases for MIR6766 Gene

Subcategory (RNA class) for MIR6766 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR6766 Gene

  • MicroRNA 6766 2 3 5
  • MicroRNA Mir-6766 3
  • Hsa-Mir-6766 3

External Ids for MIR6766 Gene

Previous GeneCards Identifiers for MIR6766 Gene

  • GC15U901717

Summaries for MIR6766 Gene

Entrez Gene Summary for MIR6766 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6766 Gene

MIR6766 (MicroRNA 6766) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR6766 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR6766 Gene

Genomics for MIR6766 Gene

Regulatory Elements for MIR6766 Gene

Enhancers for MIR6766 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH15H089332 1.2 ENCODE 0.4 -7.9 -7906 3 DMAP1 YY1 SLC30A9 ZNF143 SP3 NFYC MEF2D SSRP1 ZNF610 GLIS1 POLG LOC100631255 ENSG00000173867 TRR-TCG1-1 MIR6766
GH15H089328 0.5 ENCODE 0.7 -3.1 -3059 2 HIC1 POLR2A SPI1 POLG MIR6766
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR6766 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR6766 Gene

Chromosome:
15
Start:
89,326,739 bp from pter
End:
89,326,810 bp from pter
Size:
72 bases
Orientation:
Minus strand

Genomic View for MIR6766 Gene

Genes around MIR6766 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR6766 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6766 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6766 Gene

ORGUL Member Location for MIR6766 Gene

ORGUL Member Location for MIR6766 gene

Proteins for MIR6766 Gene

Post-translational modifications for MIR6766 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6766 Gene

Domains & Families for MIR6766 Gene

Gene Families for MIR6766 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR6766: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR6766 Gene

Function for MIR6766 Gene

Animal Model Products

miRNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6766 Gene

Localization for MIR6766 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6766 Gene

Pathways & Interactions for MIR6766 Gene

SuperPathways for MIR6766 Gene

No Data Available

Interacting Proteins for MIR6766 Gene

Gene Ontology (GO) - Biological Process for MIR6766 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR6766 Gene

Drugs & Compounds for MIR6766 Gene

No Compound Related Data Available

Transcripts for MIR6766 Gene

mRNA/cDNA for MIR6766 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6766 Gene

No ASD Table

Relevant External Links for MIR6766 Gene

GeneLoc Exon Structure for
MIR6766
ECgene alternative splicing isoforms for
MIR6766

Expression for MIR6766 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR6766 Gene:

MIR6766
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6766 Gene

Orthologs for MIR6766 Gene

Evolution for MIR6766 Gene

ENSEMBL:
Gene Tree for MIR6766 (if available)
TreeFam:
Gene Tree for MIR6766 (if available)

No data available for Orthologs for MIR6766 Gene

Paralogs for MIR6766 Gene

No data available for Paralogs for MIR6766 Gene

Variants for MIR6766 Gene

Sequence variations from dbSNP and Humsavar for MIR6766 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs113994095 Pathogenic 89,327,201(-) ATCTG(A/G)CCAAT upstream-variant-2KB, reference, missense
rs121918052 Pathogenic 89,327,006(-) AAGCA(A/C/G)AAGAA upstream-variant-2KB, reference, synonymous-codon, missense
rs121918055 Pathogenic 89,326,965(-) AGCCA(A/G)CAAGT upstream-variant-2KB, reference, missense
rs199759055 Pathogenic 89,328,699(+) CTCAC(A/G)AATGT upstream-variant-2KB, reference, missense
rs61752783 Pathogenic 89,326,947(+) CAGCC(A/C)CCTCG upstream-variant-2KB, reference, missense

Structural Variations from Database of Genomic Variants (DGV) for MIR6766 Gene

Variant ID Type Subtype PubMed ID
nsv1038140 CNV gain 25217958
nsv833086 CNV loss 17160897

Relevant External Links for MIR6766 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6766

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR6766 Gene

Disorders for MIR6766 Gene

Relevant External Links for MIR6766

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR6766

No disorders were found for MIR6766 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6766 Gene

Publications for MIR6766 Gene

  1. Discovery of hundreds of mirtrons in mouse and human small RNA data. (PMID: 22955976) Ladewig E … Lai EC (Genome research 2012) 3 60
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR6766 Gene

Sources for MIR6766 Gene

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