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Aliases for MIR676 Gene

Subcategory (RNA class) for MIR676 Gene


Quality Score for this RNA gene is


Aliases for MIR676 Gene

  • MicroRNA 676 2 3 5
  • Hsa-Mir-676 3
  • Mir-676 3

External Ids for MIR676 Gene

ORGUL Members for MIR676 Gene

Previous GeneCards Identifiers for MIR676 Gene

  • GC0XU901685
  • GC0XP069243

Summaries for MIR676 Gene

Entrez Gene Summary for MIR676 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR676 Gene

MIR676 (MicroRNA 676) is an RNA Gene, and is affiliated with the undefined RNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR676 Gene

Genomics for MIR676 Gene

Regulatory Elements for MIR676 Gene

Enhancers for MIR676 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH0XG070022 0.5 ENCODE 0.7 +0.8 756 2.5 NFIC JUND HNF4A RARA MIR676 AWAT2
GH0XG070013 0.7 ENCODE 0.4 -9.0 -9045 1.5 CTCF TAL1 DPF2 ZKSCAN1 ZNF664 TCF12 ARID1B NFIC NCOR1 PBX2 MIR676 CNOT7P1
GH0XG070029 0.7 ENCODE 0.4 +7.3 7331 0.9 ZNF263 SCRT1 CTCF ZNF654 TRIM22 REST RAD21 SCRT2 ZNF143 SMC3 MIR676 AWAT2
GH0XG069994 0.4 ENCODE 0.3 -27.6 -27592 1.8 EGR2 MIR676 CNOT7P1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR676 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR676 Gene

70,022,857 bp from pter
70,022,923 bp from pter
67 bases
Plus strand

Genomic View for MIR676 Gene

Genes around MIR676 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR676 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR676 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR676 Gene

Proteins for MIR676 Gene

Post-translational modifications for MIR676 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR676 Gene

Domains & Families for MIR676 Gene

Gene Families for MIR676 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR676: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR676 Gene

Function for MIR676 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR676 Gene

Localization for MIR676 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR676 Gene

Pathways & Interactions for MIR676 Gene

SuperPathways for MIR676 Gene

No Data Available

Interacting Proteins for MIR676 Gene

Gene Ontology (GO) - Biological Process for MIR676 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR676 Gene

Drugs & Compounds for MIR676 Gene

No Compound Related Data Available

Transcripts for MIR676 Gene

mRNA/cDNA for MIR676 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR676 Gene

No ASD Table

Relevant External Links for MIR676 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR676 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR676 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR676 Gene

Orthologs for MIR676 Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for MIR676 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ptr-mir-676 35
  • 100 (a)
(Mus musculus)
Mammalia Mir676 35
  • 69 (a)
Species where no ortholog for MIR676 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR676 Gene

Gene Tree for MIR676 (if available)
Gene Tree for MIR676 (if available)

Paralogs for MIR676 Gene

No data available for Paralogs for MIR676 Gene

Variants for MIR676 Gene

Sequence variations from dbSNP and Humsavar for MIR676 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs397516664 Likely pathogenic 70,023,246(+) GGTAA(G/T)TTCCT intron-variant, downstream-variant-500B
rs1000549229 -- 70,021,613(+) AATTC(A/G)TAAAG intron-variant, upstream-variant-2KB
rs1001847749 -- 70,023,077(+) GGATC(A/C)TTGCC intron-variant, downstream-variant-500B
rs1003391493 -- 70,021,677(+) GAGAA(A/G)GAAAA intron-variant, upstream-variant-2KB
rs1003943697 -- 70,020,979(+) GCATG(C/T)GTTTA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR676 Gene

Variant ID Type Subtype PubMed ID
esv1584074 OTHER inversion 17803354

Relevant External Links for MIR676 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR676 Gene

Disorders for MIR676 Gene

Relevant External Links for MIR676

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR676 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR676 Gene

Publications for MIR676 Gene

  1. Transcription factors are targeted by differentially expressed miRNAs in primates. (PMID: 22454130) Dannemann M. … Kelso J. (Genome Biol Evol 2012) 3 64
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  3. Deep sequencing of human nuclear and cytoplasmic small RNAs reveals an unexpectedly complex subcellular distribution of miRNAs and tRNA 3' trailers. (PMID: 20498841) Liao J.Y. … Qu L.H. (PLoS ONE 2010) 3 64
  4. Discovery of novel microRNAs in female reproductive tract using next generation sequencing. (PMID: 20224791) Creighton C.J. … Gunaratne P.H. (PLoS ONE 2010) 3 64
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR676 Gene

Sources for MIR676 Gene

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