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Aliases for MIR6745 Gene

Subcategory (RNA class) for MIR6745 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR6745 Gene

  • MicroRNA 6745 2 3 5
  • MicroRNA Mir-6745 3
  • Hsa-Mir-6745 3

External Ids for MIR6745 Gene

Previous GeneCards Identifiers for MIR6745 Gene

  • GC11U902153
  • GC11M047274
  • GC11M047944
  • GC11M050796
  • GC11M051591
  • GC11M052253
  • GC11M052913

Summaries for MIR6745 Gene

Entrez Gene Summary for MIR6745 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6745 Gene

MIR6745 (MicroRNA 6745) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR6745 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR6745 Gene

Genomics for MIR6745 Gene

Regulatory Elements for MIR6745 Gene

Enhancers for MIR6745 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11H047175 1.4 ENCODE dbSUPER 0.7 +2.0 1998 4 HNRNPUL1 HDGF PKNOX1 ARNT ARID4B SIN3A DMAP1 ZNF2 ZBTB7B YY1 NUP160 LRP4 PACSIN3 FNBP4 DDB2 RPS10P19 ENSG00000200090 ENSG00000270060 CELF1 KBTBD4
GH11H047182 2 FANTOM5 Ensembl ENCODE dbSUPER 0.4 -6.6 -6632 8 PKNOX1 FOXA2 MLX ZFP64 ARID4B SIN3A DMAP1 ZNF2 ZBTB7B YY1 ENSG00000271350 PACSIN3 LRP4 CELF1 C11orf49 MADD NR1H3 MIR6745
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR6745 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR6745 Gene

Chromosome:
11
Start:
47,179,611 bp from pter
End:
47,179,737 bp from pter
Size:
127 bases
Orientation:
Minus strand

Genomic View for MIR6745 Gene

Genes around MIR6745 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR6745 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6745 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6745 Gene

ORGUL Member Location for MIR6745 Gene

ORGUL Member Location for MIR6745 gene

Proteins for MIR6745 Gene

Post-translational modifications for MIR6745 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6745 Gene

Domains & Families for MIR6745 Gene

Gene Families for MIR6745 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR6745: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR6745 Gene

Function for MIR6745 Gene

Animal Model Products

miRNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6745 Gene

Localization for MIR6745 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6745 Gene

Pathways & Interactions for MIR6745 Gene

SuperPathways for MIR6745 Gene

No Data Available

Interacting Proteins for MIR6745 Gene

Gene Ontology (GO) - Biological Process for MIR6745 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR6745 Gene

Drugs & Compounds for MIR6745 Gene

No Compound Related Data Available

Transcripts for MIR6745 Gene

mRNA/cDNA for MIR6745 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6745 Gene

No ASD Table

Relevant External Links for MIR6745 Gene

GeneLoc Exon Structure for
MIR6745
ECgene alternative splicing isoforms for
MIR6745

Expression for MIR6745 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR6745 Gene:

MIR6745
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6745 Gene

Orthologs for MIR6745 Gene

Evolution for MIR6745 Gene

ENSEMBL:
Gene Tree for MIR6745 (if available)
TreeFam:
Gene Tree for MIR6745 (if available)

No data available for Orthologs for MIR6745 Gene

Paralogs for MIR6745 Gene

No data available for Paralogs for MIR6745 Gene

Variants for MIR6745 Gene

Sequence variations from dbSNP and Humsavar for MIR6745 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1000843883 -- 47,181,044(+) GATCA(C/T)AAGGT intron-variant, upstream-variant-2KB
rs1001294397 -- 47,180,903(+) CATTG(C/T)CAACA intron-variant, upstream-variant-2KB
rs1002424855 -- 47,181,679(+) ATTAG(C/T)CAAGT intron-variant, upstream-variant-2KB
rs1002637413 -- 47,179,781(+) TATAA(A/G)AGAGT intron-variant, upstream-variant-2KB
rs1002689739 -- 47,179,378(+) ACTAC(C/T)CCAGA intron-variant, downstream-variant-500B, upstream-variant-2KB

Relevant External Links for MIR6745 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6745

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR6745 Gene

Disorders for MIR6745 Gene

Relevant External Links for MIR6745

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR6745

No disorders were found for MIR6745 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6745 Gene

Publications for MIR6745 Gene

  1. Discovery of hundreds of mirtrons in mouse and human small RNA data. (PMID: 22955976) Ladewig E … Lai EC (Genome research 2012) 3 60
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR6745 Gene

Sources for MIR6745 Gene

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