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Aliases for MIR665 Gene

Subcategory (RNA class) for MIR665 Gene


Quality Score for this RNA gene is


Aliases for MIR665 Gene

  • MicroRNA 665 2 3
  • Hsa-Mir-665 3
  • MIRN665 3

External Ids for MIR665 Gene

ORGUL Members for MIR665 Gene

Previous HGNC Symbols for MIR665 Gene

  • MIRN665

Previous GeneCards Identifiers for MIR665 Gene

  • GC14P100415
  • GC14P101343
  • GC14P101344
  • GC14P101357
  • GC14P102120

Summaries for MIR665 Gene

Entrez Gene Summary for MIR665 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR665 Gene

MIR665 (MicroRNA 665) is an RNA Gene, and is affiliated with the undefined RNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR665 Gene

Genomics for MIR665 Gene

Genomic Location for MIR665 Gene

100,875,025 bp from pter
100,875,115 bp from pter
91 bases
Plus strand

Genomic View for MIR665 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR665 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR665 Gene

No data available for Regulatory Elements for MIR665 Gene

Proteins for MIR665 Gene

Post-translational modifications for MIR665 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR665 Gene

Domains for MIR665 Gene

Gene Families for MIR665 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR665: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR665 Gene

Function for MIR665 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR665 Gene

Localization for MIR665 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR665 Gene

Pathways for MIR665 Gene

SuperPathways for MIR665 Gene

No Data Available

Interacting Proteins for MIR665 Gene

Gene Ontology (GO) - Biological Process for MIR665 Gene


No data available for Pathways by source for MIR665 Gene

Transcripts for MIR665 Gene

mRNA/cDNA for MIR665 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR665 Gene

No ASD Table

Relevant External Links for MIR665 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR665 Gene

No Expression Related Data Available

Primer Products

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR665 Gene

Orthologs for MIR665 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR665 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia bta-mir-665 36
  • 69 (a)
(Canis familiaris)
Mammalia cfa-mir-665 36
  • 78 (a)
(Mus musculus)
Mammalia Mir665 36
  • 68 (a)
(Pan troglodytes)
Mammalia ptr-mir-665 36
  • 74 (a)
Species with no ortholog for MIR665:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR665 Gene

Gene Tree for MIR665 (if available)
Gene Tree for MIR665 (if available)

Paralogs for MIR665 Gene

No data available for Paralogs for MIR665 Gene

Variants for MIR665 Gene

Sequence variations from dbSNP and Humsavar for MIR665 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type MAF
rs576841463 -- 100,875,116(+) CTCTC(G/T)CCTTA downstream-variant-500B
rs575491659 -- 100,875,447(+) TGTGG(A/G)GAGAG downstream-variant-500B
rs572980704 -- 100,875,572(+) ATGCA(A/C)CCCTT downstream-variant-500B
rs571117183 -- 100,875,462(+) CTTGC(-/AGT)AGCTG downstream-variant-500B
rs569255987 -- 100,875,371(+) TATTG(G/T)CATCA downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR665 Gene

Variant ID Type Subtype PubMed ID
nsv902240 CNV Loss 21882294
nsv509549 CNV Insertion 20534489
nsv902241 CNV Loss 21882294
esv1002231 CNV Insertion 20482838

Relevant External Links for MIR665 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MIR665 Gene

Disorders for MIR665 Gene

No disorders were found for MIR665 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MIR665 Gene

Publications for MIR665 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  3. MicroRNA-665 is involved in the regulation of the expression of the cardioprotective cannabinoid receptor CB2 in patients with severe heart failure. (PMID: 25111814) MAPhnle P. … Kreth S. (Biochem. Biophys. Res. Commun. 2014) 3
  4. Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis. (PMID: 16954537) Berezikov E. … Cuppen E. (Genome Res. 2006) 3

Products for MIR665 Gene

Sources for MIR665 Gene

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