Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR665 Gene

Subcategory (RNA class) for MIR665 Gene

undefined

Quality Score for this RNA gene is

3

Aliases for MIR665 Gene

  • MicroRNA 665 2 3
  • Hsa-Mir-665 3
  • MIRN665 3

External Ids for MIR665 Gene

ORGUL Members for MIR665 Gene

Previous Symbols for MIR665 Gene

  • MIRN665

Summaries for MIR665 Gene

Entrez Gene Summary for MIR665 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR665 Gene

MIR665 (MicroRNA 665) is a RNA Gene, and belongs to undefined RNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR665 Gene

Genomics for MIR665 Gene

Genomic Location for MIR665 Gene

Start:
100,875,025 bp from pter
End:
100,875,115 bp from pter
Size:
91 bases
Orientation:
Plus strand

Genomic View for MIR665 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR665 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR665 Gene

No data available for Regulatory Elements for MIR665 Gene

Proteins for MIR665 Gene

Post-translational modifications for MIR665 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR665 Gene

Domains for MIR665 Gene

Gene Families for MIR665 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs
genes like me logo Genes that share domains with MIR665: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for MIR665 Gene

Function for MIR665 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR665 Gene

Localization for MIR665 Gene

No data available for Gene Ontology (GO) - Cellular Components for MIR665 Gene

Pathways for MIR665 Gene

SuperPathways for MIR665 Gene

No Data Available

Interacting Proteins for MIR665 Gene

Gene Ontology (GO) - Biological Process for MIR665 Gene

None

No data available for Pathways by source for MIR665 Gene

Transcripts for MIR665 Gene

mRNA/cDNA for MIR665 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR665 Gene

No ASD Table

Relevant External Links for MIR665 Gene

GeneLoc Exon Structure for
MIR665
ECgene alternative splicing isoforms for
MIR665

Expression for MIR665 Gene

No Expression Related Data Available

Orthologs for MIR665 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR665 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-665 37
  • 74 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-665 37
  • 69 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-665 37
  • 78 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir665 37
  • 68 (a)
OneToOne
Species with no ortholog for MIR665:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR665 Gene

ENSEMBL:
Gene Tree for MIR665 (if available)
TreeFam:
Gene Tree for MIR665 (if available)

Paralogs for MIR665 Gene

No data available for Paralogs for MIR665 Gene

Variants for MIR665 Gene

Sequence variations from dbSNP and Humsavar for MIR665 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type MAF
rs1884536 -- 100,875,439(+) GCAGC(C/G)AGTGT downstream-variant-500B
rs3935861 -- 100,875,563(+) TCCTT(C/T)CCCAT downstream-variant-500B
rs114760652 -- 100,875,234(+) GGGTA(A/C)CTGAG downstream-variant-500B
rs375720309 -- 100,875,118(+) CTCTC(C/G)TTAAA downstream-variant-500B
rs377444243 -- 100,875,305(+) TCTTC(C/T)GCCTC downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR665 Gene

Variant ID Type Subtype PubMed ID
nsv902240 CNV Loss 21882294
nsv509549 CNV Insertion 20534489
nsv902241 CNV Loss 21882294
esv1002231 CNV Insertion 20482838

Relevant External Links for MIR665 Gene

HapMap Linkage Disequilibrium report
MIR665

Disorders for MIR665 Gene

No disorders were found for MIR665 Gene.

No data available for UniProtKB/Swiss-Prot for MIR665 Gene

Publications for MIR665 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis. (PMID: 16954537) Berezikov E. … Cuppen E. (Genome Res. 2006) 3
  3. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  4. MicroRNA-665 is involved in the regulation of the expression of the cardioprotective cannabinoid receptor CB2 in patients with severe heart failure. (PMID: 25111814) MAPhnle P. … Kreth S. (Biochem. Biophys. Res. Commun. 2014) 3

Products for MIR665 Gene

Sources for MIR665 Gene

Back to Top

Content