Aliases for MIR665 Gene
Subcategory (RNA class) for MIR665 Gene
miRNA
Quality Score for this RNA gene is
3
External Ids for MIR665 Gene
- HGNC: 33662
- Entrez Gene: 100126315
- Ensembl: ENSG00000283159
- miRBase: hsa-mir-665
Previous HGNC Symbols for MIR665 Gene
- MIRN665
Previous GeneCards Identifiers for MIR665 Gene
- GC14P100415
- GC14P101343
- GC14P101344
- GC14P101357
- GC14P102120
- GC14P101222
- GC14P101376
- GC14P102054
- GC14P102327
Summaries for MIR665 Gene
-
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
GeneCards Summary for MIR665 Gene
MIR665 (MicroRNA 665) is an RNA Gene, and is affiliated with the miRNA class.
No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR665 Gene
Genomics for MIR665 Gene
Regulatory Elements for MIR665 Gene
Enhancers for MIR665 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH14F100880 | 0.2 | ENCODE | 0.4 | +5.8 | 5808 | 1.0 | GC14P102660 MIR665 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around MIR665 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for MIR665 Gene
- Chromosome:
- 14
- Start:
- 100,875,033 bp from pter
- End:
- 100,875,104 bp from pter
- Size:
- 72 bases
- Orientation:
- Plus strand
Genomic View for MIR665 Gene
Genes around MIR665 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 14q32.2 by Ensembl
- 14q32.2 by Entrez Gene
- 14q32.2 by HGNC
MIR665 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MIR665 Gene
Proteins for MIR665 Gene
Post-translational modifications for MIR665 Gene
No Post-translational modifications
Antibody Products
- Search GeneTex for Antibodies for MIR665
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR665
- Origene Custom Protein Services for MIR665
- Search GeneTex for Proteins for MIR665
Assay Products
No data available for DME Specific Peptides for MIR665 Gene
Domains & Families for MIR665 Gene
Gene Families for MIR665 Gene
- HGNC:
Graphical View of Domain Structure for InterPro Entry
No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR665 Gene
Function for MIR665 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR665
-
- Search ViGene Biosciences for MIR665
CRISPR Products
- Browse CRISPR knockouts for MIR665
miRNA Products
- Search ViGene Biosciences for MIR665
-
Origene geneexpression products in human, mouse, rat for MIR665
- Browse OriGene miRNA Products For MIR665
Inhibitory RNA Products
- Search ViGene Biosciences for MIR665
Clone Products
- GenScript: Custom all cDNA clones Services for MIR665
- VectorBuilder custom plasmid, inducible vectors for MIR665
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR665
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
- Search ViGene Biosciences for MIR665
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR665 Gene
Localization for MIR665 Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR665 Gene
Transcripts for MIR665 Gene
mRNA/cDNA for MIR665 Gene
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
- Browse CRISPR knockouts for MIR665
miRNA Products
- Search ViGene Biosciences for MIR665
-
Origene geneexpression products in human, mouse, rat for MIR665
- Browse OriGene miRNA Products For MIR665
Inhibitory RNA Products
- Search ViGene Biosciences for MIR665
Clone Products
- GenScript: Custom all cDNA clones Services for MIR665
- VectorBuilder custom plasmid, inducible vectors for MIR665
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR665
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for MIR665 Gene
NURSA nuclear receptor signaling pathways regulating expression of MIR665 Gene:
MIR665
No Expression Related Data Available
Primer Products
No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR665 Gene
Orthologs for MIR665 Gene
No data available for Orthologs for MIR665 Gene
Paralogs for MIR665 Gene
No data available for Paralogs for MIR665 Gene
Variants for MIR665 Gene
| SNP ID | Clin | Chr 14 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1077411 | -- | 100,874,235(+) | CCCCA(C/T)CCTCC | upstream-variant-2KB | |
| rs1077412 | -- | 100,874,297(+) | GGCCC(A/G)GGCCC | upstream-variant-2KB | |
| rs111300421 | -- | 100,873,341(+) | ACTAA(C/T)CCCCC | upstream-variant-2KB | |
| rs11160610 | -- | 100,873,433(+) | CTTCC(C/T)CCACC | upstream-variant-2KB | |
| rs112035429 | -- | 100,874,698(+) | TCTCT(C/T)TCTCT | downstream-variant-500B, upstream-variant-2KB |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv509549 | CNV | insertion | 20534489 |
| esv3635518 | CNV | gain | 21293372 |
| esv1002231 | CNV | insertion | 20482838 |
Relevant External Links for MIR665 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- MIR665
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR665 Gene
Disorders for MIR665 Gene
Relevant External Links for MIR665
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- MIR665
No disorders were found for MIR665 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR665 Gene
Publications for MIR665 Gene
- Identification of cardiac-related circulating microRNA profile in human chronic heart failure. (PMID: 26683101) Li H. … Wang D.W. (Oncotarget 2016) 3 64
- Screening of differential microRNA expression in gastric signet ring cell carcinoma and gastric adenocarcinoma and target gene prediction. (PMID: 25964059) Chen J. … Jiang L. (Oncol. Rep. 2015) 3 64
- MicroRNA 665 Regulates Dentinogenesis through MicroRNA-Mediated Silencing and Epigenetic Mechanisms. (PMID: 26124283) Heair H.M. … Hassan M.Q. (Mol. Cell. Biol. 2015) 3 64
- MicroRNA-665 is involved in the regulation of the expression of the cardioprotective cannabinoid receptor CB2 in patients with severe heart failure. (PMID: 25111814) MAPhnle P. … Kreth S. (Biochem. Biophys. Res. Commun. 2014) 3 64
- miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
Products for MIR665 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
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- Browse ELISpot/FluoroSpot Kits and Development Modules
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- Browse Immunoprecipitation Assays
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- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR665
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- Browse CRISPR knockouts for MIR665
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Origene geneexpression products in human, mouse, rat for MIR665
- Browse OriGene miRNA Products For MIR665
- GenScript: Custom all cDNA clones Services for MIR665
- GenScript Custom Purified and Recombinant Proteins Services for MIR665
- GenScript Custom Assay Services for MIR665
- GenScript Custom overexpressing Cell Line Services for MIR665
- Browse GenScript CRISPR for MIR665
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
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- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
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- Browse Sino Biological cDNA Clones
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- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Search ViGene Biosciences for MIR665
- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR665
- VectorBuilder custom plasmid, inducible vectors for MIR665
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR665
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for MIR665 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
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- (122) diseasecard
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- (141) ENCODE
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- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
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- (150) St John's Lab