Aliases for MIR665 Gene
Subcategory (RNA class) for MIR665 Gene
miRNA
Quality Score for this RNA gene is
3
External Ids for MIR665 Gene
- HGNC: 33662
- Entrez Gene: 100126315
- Ensembl: ENSG00000283159
- miRBase: hsa-mir-665
Previous HGNC Symbols for MIR665 Gene
- MIRN665
Previous GeneCards Identifiers for MIR665 Gene
- GC14P100415
- GC14P101343
- GC14P101344
- GC14P101357
- GC14P102120
- GC14P101222
- GC14P101376
- GC14P102054
- GC14P102327
- GC14P102497
- GC14P102673
- GC14P102845
Summaries for MIR665 Gene
-
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
GeneCards Summary for MIR665 Gene
MIR665 (MicroRNA 665) is an RNA Gene, and is affiliated with the miRNA class.
Additional gene information for MIR665 Gene
No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR665 Gene
Genomics for MIR665 Gene
GeneHancer (GH) Regulatory Elements for MIR665 Gene
Promoters and enhancers for MIR665 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH14I100880 | Enhancer | 0.2 | ENCODE | 0.4 | +5.8 | 5808 | 1 | GC14P103221 MIR431 MIR433 GC14P103199 RTL1 MIR665 ENSG00000258399 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around MIR665 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for MIR665 Gene
Genomic Locations for MIR665 Gene
- chr14:100,875,033-100,875,104
- (GRCh38/hg38)
- Size:
- 72 bases
- Orientation:
- Plus strand
- chr14:101,341,370-101,341,441
- (GRCh37/hg19)
Genomic View for MIR665 Gene
Genes around MIR665 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 14q32.2 by Ensembl
- 14q32.2 by Entrez Gene
- 14q32.2 by HGNC
MIR665 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MIR665 Gene
Proteins for MIR665 Gene
Post-translational modifications for MIR665 Gene
No Post-translational modifications
Antibody Products
- Search GeneTex for Antibodies for MIR665
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR665
- Origene Custom Protein Services for MIR665
- Search GeneTex for Proteins for MIR665
No data available for DME Specific Peptides for MIR665 Gene
Domains & Families for MIR665 Gene
Gene Families for MIR665 Gene
- HGNC:
Graphical View of Domain Structure for InterPro Entry
No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR665 Gene
Function for MIR665 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Search ViGene Biosciences for MIR665
CRISPR Products
- Browse CRISPR knockouts for MIR665
- Applied Biological Materials CRISPR for MIR665
-
Vectors and viruses for KO, Activation, Repression, and more
Inhibitory RNA Products
- Search ViGene Biosciences for MIR665
Clone Products
- GenScript: Custom all cDNA clones Services for MIR665
- Applied Biological Materials Clones for MIR665
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR665 Gene
Localization for MIR665 Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR665 Gene
Transcripts for MIR665 Gene
mRNA/cDNA for MIR665 Gene
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
- Browse CRISPR knockouts for MIR665
- Applied Biological Materials CRISPR for MIR665
-
Vectors and viruses for KO, Activation, Repression, and more
Inhibitory RNA Products
- Search ViGene Biosciences for MIR665
Clone Products
- GenScript: Custom all cDNA clones Services for MIR665
- Applied Biological Materials Clones for MIR665
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for MIR665 Gene
NURSA nuclear receptor signaling pathways regulating expression of MIR665 Gene:
MIR665
No Expression Related Data Available
Primer Products
No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR665 Gene
Orthologs for MIR665 Gene
No data available for Orthologs for MIR665 Gene
Paralogs for MIR665 Gene
No data available for Paralogs for MIR665 Gene
Variants for MIR665 Gene
| SNP ID | Clin | Chr 14 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000819601 | -- | 100,875,591(+) | G/A | downstream_transcript_variant | |
| rs1001470689 | -- | 100,874,321(+) | A/G | upstream_transcript_variant | |
| rs1001918225 | -- | 100,875,380(+) | A/C | downstream_transcript_variant | |
| rs1003087952 | -- | 100,875,271(+) | G/A | downstream_transcript_variant | |
| rs1003549805 | -- | 100,875,448(+) | G/A | downstream_transcript_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv1002231 | CNV | insertion | 20482838 |
| esv3635518 | CNV | gain | 21293372 |
| nsv509549 | CNV | insertion | 20534489 |
Additional Variant Information for MIR665 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- MIR665
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR665 Gene
Disorders for MIR665 Gene
Additional Disease Information for MIR665
No disorders were found for MIR665 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR665 Gene
Publications for MIR665 Gene
- Upregulation of miR-665 promotes apoptosis and colitis in inflammatory bowel disease by repressing the endoplasmic reticulum stress components XBP1 and ORMDL3. (PMID: 28333149) Li M … Chen M (Cell death & disease 2017) 3 58
- ΔNp63α Silences a miRNA Program to Aberrantly Initiate a Wound-Healing Program That Promotes TGFβ-Induced Metastasis. (PMID: 26988989) Rodriguez Calleja L … Ory B (Cancer research 2016) 3 58
- Identification of cardiac-related circulating microRNA profile in human chronic heart failure. (PMID: 26683101) Li H … Wang DW (Oncotarget 2016) 3 58
- MicroRNA 665 Regulates Dentinogenesis through MicroRNA-Mediated Silencing and Epigenetic Mechanisms. (PMID: 26124283) Heair HM … Hassan MQ (Molecular and cellular biology 2015) 3 58
- Screening of differential microRNA expression in gastric signet ring cell carcinoma and gastric adenocarcinoma and target gene prediction. (PMID: 25964059) Chen J … Jiang L (Oncology reports 2015) 3 58
Products for MIR665 Gene
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- Cloud-Clone Corp. disease models service
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- Search GeneTex for Antibodies for MIR665
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Sources for MIR665 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew