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Aliases for MIR665 Gene

Subcategory (RNA class) for MIR665 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR665 Gene

  • MicroRNA 665 2 3 5
  • Hsa-Mir-665 3
  • Mir-665 3
  • MIRN665 3

External Ids for MIR665 Gene

ORGUL Members for MIR665 Gene

Previous HGNC Symbols for MIR665 Gene

  • MIRN665

Previous GeneCards Identifiers for MIR665 Gene

  • GC14P100415
  • GC14P101343
  • GC14P101344
  • GC14P101357
  • GC14P102120
  • GC14P101222
  • GC14P101376
  • GC14P102054

Summaries for MIR665 Gene

Entrez Gene Summary for MIR665 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR665 Gene

MIR665 (MicroRNA 665) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR665 Gene

Genomics for MIR665 Gene

Regulatory Elements for MIR665 Gene

Enhancers for MIR665 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around MIR665 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR665 Gene

Chromosome:
14
Start:
100,875,033 bp from pter
End:
100,875,104 bp from pter
Size:
72 bases
Orientation:
Plus strand

Genomic View for MIR665 Gene

Genes around MIR665 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR665 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR665 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR665 Gene

Proteins for MIR665 Gene

Post-translational modifications for MIR665 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR665 Gene

Domains & Families for MIR665 Gene

Gene Families for MIR665 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR665: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR665 Gene

Function for MIR665 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR665 Gene

Localization for MIR665 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR665 Gene

Pathways & Interactions for MIR665 Gene

SuperPathways for MIR665 Gene

No Data Available

Interacting Proteins for MIR665 Gene

Gene Ontology (GO) - Biological Process for MIR665 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR665 Gene

Drugs & Compounds for MIR665 Gene

No Compound Related Data Available

Transcripts for MIR665 Gene

mRNA/cDNA for MIR665 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR665 Gene

No ASD Table

Relevant External Links for MIR665 Gene

GeneLoc Exon Structure for
MIR665
ECgene alternative splicing isoforms for
MIR665

Expression for MIR665 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR665 Gene:

MIR665
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR665 Gene

Orthologs for MIR665 Gene

Evolution for MIR665 Gene

ENSEMBL:
Gene Tree for MIR665 (if available)
TreeFam:
Gene Tree for MIR665 (if available)

No data available for Orthologs for MIR665 Gene

Paralogs for MIR665 Gene

No data available for Paralogs for MIR665 Gene

Variants for MIR665 Gene

Sequence variations from dbSNP and Humsavar for MIR665 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs1884536 -- 100,875,439(+) GCAGC(C/G)AGTGT downstream-variant-500B
rs3935861 -- 100,875,563(+) TCCTT(C/T)CCCAT downstream-variant-500B
rs114760652 -- 100,875,234(+) GGGTA(A/C)CTGAG downstream-variant-500B
rs529806824 -- 100,875,274(+) ACGGC(C/T)GTGGC downstream-variant-500B
rs377444243 -- 100,875,305(+) TCTTC(C/T)GCCTC downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR665 Gene

Variant ID Type Subtype PubMed ID
esv1002231 CNV insertion 20482838
esv3635518 CNV gain 21293372
nsv509549 CNV insertion 20534489

Relevant External Links for MIR665 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR665

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR665 Gene

Disorders for MIR665 Gene

Relevant External Links for MIR665

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR665

No disorders were found for MIR665 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR665 Gene

Publications for MIR665 Gene

  1. Screening of differential microRNA expression in gastric signet ring cell carcinoma and gastric adenocarcinoma and target gene prediction. (PMID: 25964059) Chen J. … Jiang L. (Oncol. Rep. 2015) 3 65
  2. MicroRNA 665 Regulates Dentinogenesis through MicroRNA-Mediated Silencing and Epigenetic Mechanisms. (PMID: 26124283) Heair H.M. … Hassan M.Q. (Mol. Cell. Biol. 2015) 3 65
  3. MicroRNA-665 is involved in the regulation of the expression of the cardioprotective cannabinoid receptor CB2 in patients with severe heart failure. (PMID: 25111814) MAPhnle P. … Kreth S. (Biochem. Biophys. Res. Commun. 2014) 3 65
  4. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 65
  5. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3 65

Products for MIR665 Gene

Sources for MIR665 Gene

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