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Aliases for MIR664B Gene

Subcategory (RNA class) for MIR664B Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR664B Gene

  • MicroRNA 664b 2 3 5
  • MicroRNA 644b 2 3
  • Hsa-Mir-644b 3
  • Hsa-Mir-664b 3
  • Mir-664b 3
  • MIR644B 3

External Ids for MIR664B Gene

Previous HGNC Symbols for MIR664B Gene

  • MIR644B

Previous GeneCards Identifiers for MIR664B Gene

  • GC0XU902007

Summaries for MIR664B Gene

Entrez Gene Summary for MIR664B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR664B Gene

MIR664B (MicroRNA 664b) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR664B include Dyskeratosis Congenita, X-Linked. Among its related pathways are rRNA processing in the nucleus and cytosol and Gene Expression.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR664B Gene

Genomics for MIR664B Gene

Genomic Location for MIR664B Gene

Chromosome:
X
Start:
154,768,596 bp from pter
End:
154,768,656 bp from pter
Size:
61 bases
Orientation:
Plus strand

Genomic View for MIR664B Gene

Genes around MIR664B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR664B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR664B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR664B Gene

No data available for Regulatory Elements for MIR664B Gene

Proteins for MIR664B Gene

Post-translational modifications for MIR664B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR664B Gene

Domains & Families for MIR664B Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR664B Gene

Function for MIR664B Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR664B Gene

Localization for MIR664B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR664B Gene

Pathways & Interactions for MIR664B Gene

genes like me logo Genes that share pathways with MIR664B: view

Pathways by source for MIR664B Gene

Interacting Proteins for MIR664B Gene

Gene Ontology (GO) - Biological Process for MIR664B Gene

None

No data available for SIGNOR curated interactions for MIR664B Gene

Drugs & Compounds for MIR664B Gene

No Compound Related Data Available

Transcripts for MIR664B Gene

mRNA/cDNA for MIR664B Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR664B Gene

No ASD Table

Relevant External Links for MIR664B Gene

GeneLoc Exon Structure for
MIR664B
ECgene alternative splicing isoforms for
MIR664B

Expression for MIR664B Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR664B Gene:

MIR664B
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR664B Gene

Orthologs for MIR664B Gene

Evolution for MIR664B Gene

ENSEMBL:
Gene Tree for MIR664B (if available)
TreeFam:
Gene Tree for MIR664B (if available)

No data available for Orthologs for MIR664B Gene

Paralogs for MIR664B Gene

No data available for Paralogs for MIR664B Gene

Variants for MIR664B Gene

Sequence variations from dbSNP and Humsavar for MIR664B Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs199422246 Pathogenic 154,767,020(+) TTGTC(C/T)GGCTG nc-transcript-variant, upstream-variant-2KB, reference, missense
rs1004384016 -- 154,768,329(+) GGCTG(A/G)CACCT nc-transcript-variant, upstream-variant-2KB, reference, missense
rs1008049790 -- 154,767,923(+) TCGGC(C/T)CACTG intron-variant, upstream-variant-2KB
rs1009940831 -- 154,766,837(+) CCCAC(A/G)TCATC intron-variant, nc-transcript-variant, upstream-variant-2KB
rs1014457257 -- 154,767,820(+) AAATT(A/C)TGCTA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR664B Gene

Variant ID Type Subtype PubMed ID
esv33784 CNV gain+loss 17666407

Relevant External Links for MIR664B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR664B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR664B Gene

Disorders for MIR664B Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR664B Gene - From: GeneCards

Disorder Aliases PubMed IDs
dyskeratosis congenita, x-linked
  • hhs
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for MIR664B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR664B
genes like me logo Genes that share disorders with MIR664B: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR664B Gene

Publications for MIR664B Gene

  1. Mir-664 promotes osteosarcoma cells proliferation via downregulating of FOXO4. (PMID: 26463624) Chen B. … Chen J. (Biomed. Pharmacother. 2015) 3 64
  2. miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. (PMID: 21911355) FriedlAonder M.R. … Rajewsky N. (Nucleic Acids Res. 2012) 3 64
  3. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR664B Gene

Sources for MIR664B Gene

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