Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR664A Gene

Subcategory (RNA class) for MIR664A Gene

snoRNA

Quality Score for this RNA gene is

8

Aliases for MIR664A Gene

  • MicroRNA 664a 2 3 5
  • MicroRNA 664 2 3
  • Hsa-Mir-664a 3
  • Hsa-Mir-664 3
  • Mir-664a 3
  • MIRN664 3
  • MIR664 3

External Ids for MIR664A Gene

Previous HGNC Symbols for MIR664A Gene

  • MIRN664
  • MIR664

Previous GeneCards Identifiers for MIR664A Gene

  • GC01M220378

Summaries for MIR664A Gene

Entrez Gene Summary for MIR664A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR664A Gene

MIR664A (MicroRNA 664a) is an RNA Gene, and is affiliated with the snoRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR664A Gene

Genomics for MIR664A Gene

Genomic Location for MIR664A Gene

Chromosome:
1
Start:
220,200,538 bp from pter
End:
220,200,619 bp from pter
Size:
82 bases
Orientation:
Minus strand

Genomic View for MIR664A Gene

Genes around MIR664A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR664A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR664A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR664A Gene

ORGUL Member Location for MIR664A Gene

ORGUL Member Location for MIR664A gene

No data available for Regulatory Elements for MIR664A Gene

Proteins for MIR664A Gene

Post-translational modifications for MIR664A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR664A Gene

Domains & Families for MIR664A Gene

Gene Families for MIR664A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR664A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR664A Gene

Function for MIR664A Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR664A Gene

Localization for MIR664A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR664A Gene

Pathways & Interactions for MIR664A Gene

SuperPathways for MIR664A Gene

No Data Available

Interacting Proteins for MIR664A Gene

Gene Ontology (GO) - Biological Process for MIR664A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR664A Gene

Drugs & Compounds for MIR664A Gene

No Compound Related Data Available

Transcripts for MIR664A Gene

mRNA/cDNA for MIR664A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR664A Gene

No ASD Table

Relevant External Links for MIR664A Gene

GeneLoc Exon Structure for
MIR664A
ECgene alternative splicing isoforms for
MIR664A

Expression for MIR664A Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR664A Gene:

MIR664A
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR664A Gene

Orthologs for MIR664A Gene

Evolution for MIR664A Gene

ENSEMBL:
Gene Tree for MIR664A (if available)
TreeFam:
Gene Tree for MIR664A (if available)

No data available for Orthologs for MIR664A Gene

Paralogs for MIR664A Gene

No data available for Paralogs for MIR664A Gene

Variants for MIR664A Gene

Sequence variations from dbSNP and Humsavar for MIR664A Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs797045103 Likely pathogenic 220,202,376(-) TTGGT(A/G)GCTGC upstream-variant-2KB, splice-acceptor-variant
rs76473498 Likely benign 220,202,386(+) AAGAT(A/G)AAATA intron-variant, upstream-variant-2KB
rs576411922 Uncertain significance 220,202,313(+) TCTTG(C/T)AGACC upstream-variant-2KB, reference, synonymous-codon
rs1003229364 -- 220,201,853(+) GTCTC(A/T)CTAAA intron-variant, upstream-variant-2KB
rs1004621918 -- 220,201,140(+) CAGTA(C/T)CTAAC intron-variant, upstream-variant-2KB

Relevant External Links for MIR664A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR664A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR664A Gene

Disorders for MIR664A Gene

Relevant External Links for MIR664A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR664A

No disorders were found for MIR664A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR664A Gene

Publications for MIR664A Gene

  1. Overexpression of miR-664 is associated with enhanced osteosarcoma cell migration and invasion ability via targeting SOX7. (PMID: 26515813) Bao Y. … Chen J. (Clin. Exp. Med. 2017) 3 64
  2. High-throughput qRT-PCR validation of blood microRNAs in non-small cell lung cancer. (PMID: 26672767) Leidinger P. … Keller A. (Oncotarget 2016) 3 64
  3. miR-664 negatively regulates PLP2 and promotes cell proliferation and invasion in T-cell acute lymphoblastic leukaemia. (PMID: 25735976) Zhu H. … Shao X.J. (Biochem. Biophys. Res. Commun. 2015) 3 64
  4. Loss of MiR-664 Expression Enhances Cutaneous Malignant Melanoma Proliferation by Upregulating PLP2. (PMID: 26287415) Ding Z. … Zhou M. (Medicine (Baltimore) 2015) 3 64
  5. Mir-664 promotes osteosarcoma cells proliferation via downregulating of FOXO4. (PMID: 26463624) Chen B. … Chen J. (Biomed. Pharmacother. 2015) 3 64

Products for MIR664A Gene

Sources for MIR664A Gene

Content
Loading form....