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Aliases for MIR663A Gene

Subcategory (RNA class) for MIR663A Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR663A Gene

  • MicroRNA 663a 2 3
  • MicroRNA 663 2 3
  • Hsa-Mir-663a 3
  • Hsa-Mir-663 3
  • Mir-663a 3
  • MIRN663 3
  • MIR663 3

External Ids for MIR663A Gene

Previous HGNC Symbols for MIR663A Gene

  • MIRN663
  • MIR663

Summaries for MIR663A Gene

Entrez Gene Summary for MIR663A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR663A Gene

MIR663A (MicroRNA 663a) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR663A Gene

Genomics for MIR663A Gene

Genomic Location for MIR663A Gene

Chromosome:
20
Start:
26,208,186 bp from pter
End:
26,208,278 bp from pter
Size:
93 bases
Orientation:
Minus strand

Genomic View for MIR663A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR663A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR663A Gene

No data available for Regulatory Elements for MIR663A Gene

Proteins for MIR663A Gene

Post-translational modifications for MIR663A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR663A Gene

Domains & Families for MIR663A Gene

Gene Families for MIR663A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR663A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR663A Gene

Function for MIR663A Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR663A Gene

Localization for MIR663A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR663A Gene

Pathways & Interactions for MIR663A Gene

SuperPathways for MIR663A Gene

No Data Available

Interacting Proteins for MIR663A Gene

Gene Ontology (GO) - Biological Process for MIR663A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR663A Gene

Drugs & Compounds for MIR663A Gene

No Compound Related Data Available

Transcripts for MIR663A Gene

mRNA/cDNA for MIR663A Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR663A Gene

No ASD Table

Relevant External Links for MIR663A Gene

GeneLoc Exon Structure for
MIR663A
ECgene alternative splicing isoforms for
MIR663A

Expression for MIR663A Gene

mRNA differential expression in normal tissues according to GTEx for MIR663A Gene

This gene is overexpressed in Testis (x47.2).

Primer Products

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR663A Gene

Orthologs for MIR663A Gene

Evolution for MIR663A Gene

ENSEMBL:
Gene Tree for MIR663A (if available)
TreeFam:
Gene Tree for MIR663A (if available)

No data available for Orthologs for MIR663A Gene

Paralogs for MIR663A Gene

No data available for Paralogs for MIR663A Gene

Variants for MIR663A Gene

Relevant External Links for MIR663A Gene

HapMap Linkage Disequilibrium report
MIR663A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR663A Gene

Disorders for MIR663A Gene

Relevant External Links for MIR663A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR663A
genes like me logo Genes that share disorders with MIR663A: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR663A Gene

Publications for MIR663A Gene

  1. Waltonitone induces apoptosis through mir-663-induced Bcl-2 downregulation in non-small cell lung cancer. (PMID: 25301444) Zhang Y. … He P. (Tumour Biol. 2015) 67
  2. miR-663 induces castration-resistant prostate cancer transformation and predicts clinical recurrence. (PMID: 24243035) Jiao L. … Sun Y. (J. Cell. Physiol. 2014) 67
  3. MicroRNA-663 induction upon oxidative stress in cultured human fibroblasts depends on the chronological age of the donor. (PMID: 24664125) Waaijer M.E. … Maier A.B. (Biogerontology 2014) 67
  4. Primate-specific miR-663 functions as a tumor suppressor by targeting PIK3CD and predicts the prognosis of human glioblastoma. (PMID: 24523440) Shi Y. … Bian X.W. (Clin. Cancer Res. 2014) 67
  5. MicroRNA-663 regulates human vascular smooth muscle cell phenotypic switch and vascular neointimal formation. (PMID: 24014830) Li P. … Sun J. (Circ. Res. 2013) 67

Products for MIR663A Gene

Sources for MIR663A Gene

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