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Aliases for MIR663A Gene

Subcategory (RNA class) for MIR663A Gene


Quality Score for this RNA gene is


Aliases for MIR663A Gene

  • MicroRNA 663a 2 3
  • MicroRNA 663 2 3
  • MIR663A Host Gene 5
  • Hsa-Mir-663a 3
  • Hsa-Mir-663 3
  • MIR663AHG 5
  • Mir-663a 3
  • MIRN663 3
  • MIR663 3

External Ids for MIR663A Gene

Previous HGNC Symbols for MIR663A Gene

  • MIRN663
  • MIR663

Summaries for MIR663A Gene

Entrez Gene Summary for MIR663A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR663A Gene

MIR663A (MicroRNA 663a) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR663A Gene

Genomics for MIR663A Gene

Genomic Location for MIR663A Gene

26,186,920 bp from pter
26,251,526 bp from pter
64,607 bases
Minus strand

Genomic View for MIR663A Gene

Genes around MIR663A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR663A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR663A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR663A Gene

No data available for Regulatory Elements for MIR663A Gene

Proteins for MIR663A Gene

Post-translational modifications for MIR663A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR663A Gene

Domains & Families for MIR663A Gene

Gene Families for MIR663A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR663A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR663A Gene

Function for MIR663A Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR663A Gene

Localization for MIR663A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR663A Gene

Pathways & Interactions for MIR663A Gene

SuperPathways for MIR663A Gene

No Data Available

Interacting Proteins for MIR663A Gene

Gene Ontology (GO) - Biological Process for MIR663A Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR663A Gene

Transcripts for MIR663A Gene

mRNA/cDNA for MIR663A Gene

(38) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR663A Gene

No ASD Table

Relevant External Links for MIR663A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR663A Gene

mRNA differential expression in normal tissues according to GTEx for MIR663A Gene

This gene is overexpressed in Testis (x47.2).

NURSA nuclear receptor signaling pathways regulating expression of MIR663A Gene:


No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR663A Gene

Orthologs for MIR663A Gene

Evolution for MIR663A Gene

Gene Tree for MIR663A (if available)
Gene Tree for MIR663A (if available)

No data available for Orthologs for MIR663A Gene

Paralogs for MIR663A Gene

No data available for Paralogs for MIR663A Gene

Variants for MIR663A Gene

Sequence variations from dbSNP and Humsavar for MIR663A Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type
rs10153996 -- 26,209,230(+) CCCAA(A/G)CCCAC nc-transcript-variant, upstream-variant-2KB
rs10432759 -- 26,209,037(+) TCGCG(G/T)TCAGG intron-variant, upstream-variant-2KB
rs11087546 -- 26,209,188(+) AACGG(C/T)AGCCC nc-transcript-variant, upstream-variant-2KB
rs111569479 -- 26,208,574(+) GAACG(C/G)TGCGC intron-variant, upstream-variant-2KB
rs111662604 -- 26,209,623(+) CAGGA(A/G)GCGAG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR663A Gene

Variant ID Type Subtype PubMed ID
nsv9799 CNV gain 18304495
nsv585776 CNV loss 21841781
nsv585774 CNV gain 21841781
nsv585761 CNV gain 21841781
nsv470545 CNV gain 18288195
nsv458959 CNV loss 19166990
nsv1062308 CNV gain 25217958
nsv1060178 CNV gain 25217958
esv3893329 CNV gain 25118596
esv3893328 CNV gain 25118596
esv3645613 CNV gain 21293372
esv33036 CNV gain 17666407
esv2763226 CNV gain 21179565
esv2758790 CNV gain+loss 17122850
dgv7526n54 CNV gain 21841781
dgv509n27 CNV gain 19166990
dgv4292n100 CNV gain 25217958

Relevant External Links for MIR663A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR663A Gene

Disorders for MIR663A Gene

Relevant External Links for MIR663A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR663A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR663A Gene

Publications for MIR663A Gene

  1. MicroRNA-663 inhibits the proliferation, migration and invasion of glioblastoma cells via targeting TGF-I^1. (PMID: 26717894) Li Q. … Jiang B. (Oncol. Rep. 2016) 3 64
  2. MicroRNA-663 activates the canonical Wnt signaling through the adenomatous polyposis coli suppression. (PMID: 26028359) Miao C.G. … Li J. (Immunol. Lett. 2015) 3 64
  3. miR-663 Suppresses Oncogenic Function of CXCR4 in Glioblastoma. (PMID: 26023083) Shi Y. … Bian X.W. (Clin. Cancer Res. 2015) 3 64
  4. miR-663 attenuates tumor growth and invasiveness by targeting eEF1A2 in pancreatic cancer. (PMID: 25744894) Zang W. … Zhao G. (Mol. Cancer 2015) 3 64
  5. APP intracellular domain acts as a transcriptional regulator of miR-663 suppressing neuronal differentiation. (PMID: 25695604) Shu R. … Xiao Z.C. (Cell Death Dis 2015) 3 64

Products for MIR663A Gene

Sources for MIR663A Gene

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