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Aliases for MIR661 Gene

Subcategory (RNA class) for MIR661 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR661 Gene

  • MicroRNA 661 2 3
  • MIRN661 3 6
  • Hsa-Mir-661 3

External Ids for MIR661 Gene

Previous Symbols for MIR661 Gene

  • MIRN661

Summaries for MIR661 Gene

Entrez Gene Summary for MIR661 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR661 Gene

MIR661 (MicroRNA 661) is a RNA Gene, and belongs to miRNA RNA class.

fRNAdb sequence ontologies for MIR661 Gene

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR661

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR661 Gene

Genomics for MIR661 Gene

Genomic Location for MIR661 Gene

Start:
143,945,191 bp from pter
End:
143,945,279 bp from pter
Size:
89 bases
Orientation:
Minus strand

Genomic View for MIR661 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR661 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR661 Gene

ORGUL Member Location for MIR661 Gene

ORGUL Member Location for MIR661 gene

No data available for Regulatory Elements for MIR661 Gene

Proteins for MIR661 Gene

Post-translational modifications for MIR661 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR661 Gene

Domains for MIR661 Gene

Gene Families for MIR661 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs
genes like me logo Genes that share domains with MIR661: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for MIR661 Gene

Function for MIR661 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR661 Gene

Localization for MIR661 Gene

No data available for Gene Ontology (GO) - Cellular Components for MIR661 Gene

Pathways for MIR661 Gene

SuperPathways for MIR661 Gene

No Data Available

Interacting Proteins for MIR661 Gene

Gene Ontology (GO) - Biological Process for MIR661 Gene

None

No data available for Pathways by source for MIR661 Gene

Transcripts for MIR661 Gene

fRNAdb Secondary structures for MIR661 Gene

  • FR311315

mRNA/cDNA for MIR661 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR661 Gene

No ASD Table

Relevant External Links for MIR661 Gene

GeneLoc Exon Structure for
MIR661
ECgene alternative splicing isoforms for
MIR661

Expression for MIR661 Gene

mRNA expression in normal human tissues for MIR661 Gene

genes like me logo Genes that share expressions with MIR661: view

Orthologs for MIR661 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR661 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-661 37
  • 91 (a)
OneToOne
Species with no ortholog for MIR661:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR661 Gene

ENSEMBL:
Gene Tree for MIR661 (if available)
TreeFam:
Gene Tree for MIR661 (if available)

Paralogs for MIR661 Gene

No data available for Paralogs for MIR661 Gene

Variants for MIR661 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR661 Gene

Variant ID Type Subtype PubMed ID
dgv7935n71 CNV Loss 21882294
dgv7940n71 CNV Loss 21882294
dgv7943n71 CNV Loss 21882294
nsv891766 CNV Loss 21882294
dgv906n27 CNV Loss 19166990
nsv470249 CNV Loss 18288195
dgv7947n71 CNV Loss 21882294
dgv7948n71 CNV Loss 21882294
dgv7949n71 CNV Loss 21882294
dgv7950n71 CNV Loss 21882294
dgv7951n71 CNV Gain+Loss 21882294
nsv891787 CNV Gain+Loss 21882294
nsv515809 CNV Gain+Loss 19592680
dgv7952n71 CNV Loss 21882294
nsv824794 CNV Gain 20364138
nsv470250 CNV Gain 18288195

Relevant External Links for MIR661 Gene

HapMap Linkage Disequilibrium report
MIR661

No data available for Sequence variations from dbSNP and Humsavar for MIR661 Gene

Disorders for MIR661 Gene

No disorders were found for MIR661 Gene.

No data available for UniProtKB/Swiss-Prot for MIR661 Gene

Publications for MIR661 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. The colorectal microRNAome. (PMID: 16505370) Cummins J.M. … Velculescu V.E. (Proc. Natl. Acad. Sci. U.S.A. 2006) 3
  3. MicroRNA-661, a c/EBPalpha target, inhibits metastatic tumor antigen 1 and regulates its functions. (PMID: 19584269) Reddy S.D. … Kumar R. (Cancer Res. 2009) 3
  4. miR-661 expression in SNAI1-induced epithelial to mesenchymal transition contributes to breast cancer cell invasion by targeting Nectin-1 and StarD10 messengers. (PMID: 20543867) Vetter G. … Friederich E. (Oncogene 2010) 3
  5. Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease. (PMID: 23969696) Sabater-Lleal M. … O'Donnell C.J. (Circulation 2013) 3

Products for MIR661 Gene

Sources for MIR661 Gene

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