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Aliases for MIR660 Gene

Subcategory (RNA class) for MIR660 Gene


Quality Score for this RNA gene is


Aliases for MIR660 Gene

  • MicroRNA 660 2 3 5
  • Hsa-Mir-660 3
  • Mir-660 3
  • MIRN660 3

External Ids for MIR660 Gene

ORGUL Members for MIR660 Gene

Previous HGNC Symbols for MIR660 Gene

  • MIRN660

Previous GeneCards Identifiers for MIR660 Gene

  • GC0XP049668
  • GC0XP049777

Summaries for MIR660 Gene

Entrez Gene Summary for MIR660 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR660 Gene

MIR660 (MicroRNA 660) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR660 Gene

Genomics for MIR660 Gene

Genomic Location for MIR660 Gene

50,013,241 bp from pter
50,013,337 bp from pter
97 bases
Plus strand

Genomic View for MIR660 Gene

Genes around MIR660 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR660 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR660 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR660 Gene

No data available for Regulatory Elements for MIR660 Gene

Proteins for MIR660 Gene

Post-translational modifications for MIR660 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR660 Gene

Domains & Families for MIR660 Gene

Gene Families for MIR660 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR660: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR660 Gene

Function for MIR660 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR660 Gene

Localization for MIR660 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR660 Gene

Pathways & Interactions for MIR660 Gene

SuperPathways for MIR660 Gene

No Data Available

Interacting Proteins for MIR660 Gene

Gene Ontology (GO) - Biological Process for MIR660 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR660 Gene

Transcripts for MIR660 Gene

mRNA/cDNA for MIR660 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR660 Gene

No ASD Table

Relevant External Links for MIR660 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR660 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR660 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR660 Gene:

genes like me logo Genes that share expression patterns with MIR660: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR660 Gene

Orthologs for MIR660 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR660 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ptr-mir-660 35
  • 100 (a)
(Bos Taurus)
Mammalia bta-mir-660 35
  • 89 (a)
Species where no ortholog for MIR660 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR660 Gene

Gene Tree for MIR660 (if available)
Gene Tree for MIR660 (if available)

Paralogs for MIR660 Gene

No data available for Paralogs for MIR660 Gene

Variants for MIR660 Gene

Sequence variations from dbSNP and Humsavar for MIR660 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs111504692 -- 50,013,009(+) TCCAC(C/T)TCCTC intron-variant, upstream-variant-2KB
rs113268982 -- 50,013,670(+) CACAC(A/C)CACTC intron-variant, downstream-variant-500B, upstream-variant-2KB
rs138811624 -- 50,012,429(+) TATGG(C/T)CATAG intron-variant, upstream-variant-2KB
rs142931336 -- 50,013,734(+) CTAGC(C/G)TTGCA intron-variant, downstream-variant-500B, upstream-variant-2KB
rs145629523 -- 50,011,425(+) ATGAA(A/G)TAGAT intron-variant, upstream-variant-2KB

Relevant External Links for MIR660 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR660 Gene

Disorders for MIR660 Gene

Relevant External Links for MIR660

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR660 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR660 Gene

Publications for MIR660 Gene

  1. Identification of cardiac-related circulating microRNA profile in human chronic heart failure. (PMID: 26683101) Li H. … Wang D.W. (Oncotarget 2016) 3 64
  2. Combination of serum miRNAs with Cyfra21-1 for the diagnosis of non-small cell lung cancer. (PMID: 26213369) Zhou C. … He J. (Cancer Lett. 2015) 3 64
  3. Next generation sequencing profiling identifies miR-574-3p and miR-660-5p as potential novel prognostic markers for breast cancer. (PMID: 26416693) Krishnan P. … Damaraju S. (BMC Genomics 2015) 3 64
  4. Sex differences in the genome-wide DNA methylation pattern and impact on gene expression, microRNA levels and insulin secretion in human pancreatic islets. (PMID: 25517766) Hall E. … Ling C. (Genome Biol. 2014) 3 64
  5. Mir-660 is downregulated in lung cancer patients and its replacement inhibits lung tumorigenesis by targeting MDM2-p53 interaction. (PMID: 25501825) Fortunato O. … Sozzi G. (Cell Death Dis 2014) 3 64

Products for MIR660 Gene

Sources for MIR660 Gene

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