Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR658 Gene

Subcategory (RNA class) for MIR658 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR658 Gene

  • MicroRNA 658 2 3
  • Hsa-Mir-658 3
  • MIRN658 3

External Ids for MIR658 Gene

Previous HGNC Symbols for MIR658 Gene

  • MIRN658

Previous GeneCards Identifiers for MIR658 Gene

  • GC22M036571
  • GC22M038241
  • GC22M038314
  • GC22M039043
  • GC22M039413
  • GC22M040091

Summaries for MIR658 Gene

Entrez Gene Summary for MIR658 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR658 Gene

MIR658 (MicroRNA 658) is an RNA Gene, and is affiliated with the miRNA class.

fRNAdb sequence ontologies for MIR658 Gene - the ORGUL cluster for this gene includes several descriptions:

  • miRNA: Small, ~22-nt, RNA molecule that is the endogenous transcript of a miRNA gene. Micro RNAs are produced from precursor molecules (SO:0000647) that can form local hairpin structures, which ordinarily are processed (via the Dicer pathway) such that a single miRNA molecule accumulates from one arm of a hairpin precursor molecule. Micro RNAs may trigger the cleavage of their target molecules or act as translational repressors.

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR658

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR658 Gene

Genomics for MIR658 Gene

Genomic Location for MIR658 Gene

Start:
37,844,272 bp from pter
End:
37,844,371 bp from pter
Size:
100 bases
Orientation:
Minus strand

Genomic View for MIR658 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR658 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR658 Gene

ORGUL Member Location for MIR658 Gene

ORGUL Member Location for MIR658 gene

No data available for Regulatory Elements for MIR658 Gene

Proteins for MIR658 Gene

Post-translational modifications for MIR658 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR658 Gene

Domains for MIR658 Gene

Gene Families for MIR658 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR658: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR658 Gene

Function for MIR658 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR658 Gene

Localization for MIR658 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR658 Gene

Pathways for MIR658 Gene

SuperPathways for MIR658 Gene

No Data Available

Interacting Proteins for MIR658 Gene

Gene Ontology (GO) - Biological Process for MIR658 Gene

None

No data available for Pathways by source for MIR658 Gene

Transcripts for MIR658 Gene

fRNAdb Secondary structures for MIR658 Gene

  • hsa-miR-658_MIMAT0003336_Homo_sapiens_miR-658_mature

mRNA/cDNA for MIR658 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR658 Gene

No ASD Table

Relevant External Links for MIR658 Gene

GeneLoc Exon Structure for
MIR658
ECgene alternative splicing isoforms for
MIR658

Expression for MIR658 Gene

mRNA expression in normal human tissues for MIR658 Gene

genes like me logo Genes that share expressions with MIR658: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR658 Gene

Orthologs for MIR658 Gene

Evolution for MIR658 Gene

ENSEMBL:
Gene Tree for MIR658 (if available)
TreeFam:
Gene Tree for MIR658 (if available)

No data available for Orthologs for MIR658 Gene

Paralogs for MIR658 Gene

No data available for Paralogs for MIR658 Gene

Variants for MIR658 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR658 Gene

Variant ID Type Subtype PubMed ID
dgv4965n71 CNV Loss 21882294
nsv915035 CNV Loss 21882294
dgv1406e1 CNV Complex 17122850
dgv4966n71 CNV Loss 21882294
esv2666189 CNV Deletion 23128226

Relevant External Links for MIR658 Gene

HapMap Linkage Disequilibrium report
MIR658

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for MIR658 Gene

Disorders for MIR658 Gene

No disorders were found for MIR658 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MIR658 Gene

Publications for MIR658 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. The colorectal microRNAome. (PMID: 16505370) Cummins J.M. … Velculescu V.E. (Proc. Natl. Acad. Sci. U.S.A. 2006) 3

Products for MIR658 Gene

Sources for MIR658 Gene

Back to Top

Content