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Aliases for MIR655 Gene

Subcategory (RNA class) for MIR655 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR655 Gene

  • MicroRNA 655 2 3 5
  • Hsa-Mir-655 3
  • Mir-655 3
  • MIRN655 3

External Ids for MIR655 Gene

ORGUL Members for MIR655 Gene

Previous HGNC Symbols for MIR655 Gene

  • MIRN655

Previous GeneCards Identifiers for MIR655 Gene

  • GC14P100829
  • GC14P100919
  • GC14P101520
  • GC14P101549
  • GC14P101584
  • GC14P101623
  • GC14P101651
  • GC14P101684
  • GC14P101721
  • GC14P101763
  • GC14P101821
  • GC14P101961
  • GC14P102158
  • GC14P101261
  • GC14P101872
  • GC14P102192
  • GC14P102360
  • GC14P102531
  • GC14P102710

Summaries for MIR655 Gene

Entrez Gene Summary for MIR655 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR655 Gene

MIR655 (MicroRNA 655) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR655 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR655 Gene

Genomics for MIR655 Gene

Regulatory Elements for MIR655 Gene

Enhancers for MIR655 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14H101287 1 ENCODE 9.4 +239.4 239371 2 FOXA2 ATF1 MLX ZFP64 ARID4B YY1 SP5 ZHX2 NFYC REST MEG3 MIR1185-2 MIR381 MIR487B MIR539 MIR544A MIR889 MIR655 MIR1185-1 MIR300
GH14H101004 0.8 Ensembl ENCODE 10.9 -44.5 -44466 1 GATA3 MNT MYC TCF7L2 MIR134 MIR487A MIR154 MIR323B MIR485 MIR377 MIR496 MIR376C MIR1185-1 MIR1185-2
GH14H101096 0.8 FANTOM5 ENCODE 10.7 +48.8 48798 3 POLR2A JUN MAFK RTL1 LOC105370670 MEG9 MIR369 MIR409 MIR410 MIR412 MIR541 MIR656 MIR154
GH14H101330 0.9 ENCODE 8.9 +281.3 281305 0 ELF3 FOXA2 MLX ARID4B RAD21 THRB ZSCAN9 RARA CREM MIXL1 MIR1185-1 MIR1185-2 MIR300 MIR381 MIR487B MIR539 MIR544A MIR655 MIR889 MIR376C
GH14H101333 0.9 ENCODE 8.9 +285.5 285507 2 ELF3 FOXA2 ARID4B ZSCAN9 RAD21 RARA YY1 CREM MIXL1 THAP11 MIR381 MIR487B MIR539 MIR544A MIR655 MIR889 MIR376C MIR1185-1 MIR1185-2 MIR300
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR655 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR655 Gene

Chromosome:
14
Start:
101,049,550 bp from pter
End:
101,049,646 bp from pter
Size:
97 bases
Orientation:
Plus strand

Genomic View for MIR655 Gene

Genes around MIR655 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR655 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR655 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR655 Gene

Proteins for MIR655 Gene

Post-translational modifications for MIR655 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR655 Gene

Domains & Families for MIR655 Gene

Gene Families for MIR655 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR655: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR655 Gene

Function for MIR655 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR655
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR655 Gene

Localization for MIR655 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR655 Gene

Pathways & Interactions for MIR655 Gene

SuperPathways for MIR655 Gene

No Data Available

Interacting Proteins for MIR655 Gene

Gene Ontology (GO) - Biological Process for MIR655 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR655 Gene

Drugs & Compounds for MIR655 Gene

No Compound Related Data Available

Transcripts for MIR655 Gene

mRNA/cDNA for MIR655 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR655
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR655 Gene

No ASD Table

Relevant External Links for MIR655 Gene

GeneLoc Exon Structure for
MIR655
ECgene alternative splicing isoforms for
MIR655

Expression for MIR655 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR655 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR655 Gene:

MIR655
genes like me logo Genes that share expression patterns with MIR655: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR655 Gene

Orthologs for MIR655 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR655 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-655 34
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-655 34
  • 93 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 34
  • 93 (a)
OneToOne
Species where no ortholog for MIR655 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR655 Gene

ENSEMBL:
Gene Tree for MIR655 (if available)
TreeFam:
Gene Tree for MIR655 (if available)

Paralogs for MIR655 Gene

No data available for Paralogs for MIR655 Gene

Variants for MIR655 Gene

Sequence variations from dbSNP and Humsavar for MIR655 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs1000110976 -- 101,049,759(+) GGCTG(A/G)TGGAG intron-variant, downstream-variant-500B
rs1001499669 -- 101,048,356(+) GTATG(A/G)AACAC intron-variant, downstream-variant-500B, upstream-variant-2KB
rs1003276587 -- 101,049,769(+) GGGAA(C/G)AGCCC intron-variant, downstream-variant-500B
rs1005375970 -- 101,048,031(+) GGGGA(C/T)ATTGG intron-variant, downstream-variant-500B, upstream-variant-2KB
rs1006180383 -- 101,049,701(+) TGAGC(C/T)GAGAG intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR655 Gene

Variant ID Type Subtype PubMed ID
esv3635521 CNV gain 21293372
nsv1040993 CNV gain 25217958
nsv565859 CNV gain 21841781
nsv565860 CNV gain 21841781

Relevant External Links for MIR655 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR655

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR655 Gene

Disorders for MIR655 Gene

Relevant External Links for MIR655

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR655

No disorders were found for MIR655 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR655 Gene

Publications for MIR655 Gene

  1. miR-655 suppresses epithelial-to-mesenchymal transition by targeting Prrx1 in triple-negative breast cancer. (PMID: 26820102) Lv ZD … Wang HB (Journal of cellular and molecular medicine 2016) 3 60
  2. The PTTG1-targeting miRNAs miR-329, miR-300, miR-381, and miR-655 inhibit pituitary tumor cell tumorigenesis and are involved in a p53/PTTG1 regulation feedback loop. (PMID: 26320179) Liang HQ … Zhang S (Oncotarget 2015) 3 60
  3. MiR-134/487b/655 cluster regulates TGF-β-induced epithelial-mesenchymal transition and drug resistance to gefitinib by targeting MAGI2 in lung adenocarcinoma cells. (PMID: 24258346) Kitamura K … Gemma A (Molecular cancer therapeutics 2014) 3 60
  4. Birth and expression evolution of mammalian microRNA genes. (PMID: 23034410) Meunier J … Kaessmann H (Genome research 2013) 3 60
  5. Mir-655 up-regulation suppresses cell invasion by targeting pituitary tumor-transforming gene-1 in esophageal squamous cell carcinoma. (PMID: 24314023) Wang Y … Zhao G (Journal of translational medicine 2013) 3 60

Products for MIR655 Gene

Sources for MIR655 Gene

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