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Aliases for MIR653 Gene

Subcategory (RNA class) for MIR653 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR653 Gene

  • MicroRNA 653 2 3
  • Hsa-Mir-653 3
  • MIRN653 3

External Ids for MIR653 Gene

Previous HGNC Symbols for MIR653 Gene

  • MIRN653

Previous GeneCards Identifiers for MIR653 Gene

  • GC07M092952
  • GC07M093112

Summaries for MIR653 Gene

Entrez Gene Summary for MIR653 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR653 Gene

MIR653 (MicroRNA 653) is an RNA Gene, and is affiliated with the miRNA class.

fRNAdb sequence ontologies for MIR653 Gene

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR653

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR653 Gene

Genomics for MIR653 Gene

Genomic Location for MIR653 Gene

Start:
93,482,760 bp from pter
End:
93,482,855 bp from pter
Size:
96 bases
Orientation:
Minus strand

Genomic View for MIR653 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR653 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR653 Gene

ORGUL Member Location for MIR653 Gene

ORGUL Member Location for MIR653 gene

No data available for Regulatory Elements for MIR653 Gene

Proteins for MIR653 Gene

Post-translational modifications for MIR653 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR653 Gene

Domains for MIR653 Gene

Gene Families for MIR653 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR653: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR653 Gene

Function for MIR653 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR653 Gene

Localization for MIR653 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR653 Gene

Pathways for MIR653 Gene

SuperPathways for MIR653 Gene

No Data Available

Interacting Proteins for MIR653 Gene

Gene Ontology (GO) - Biological Process for MIR653 Gene

None

No data available for Pathways by source for MIR653 Gene

Transcripts for MIR653 Gene

fRNAdb Secondary structures for MIR653 Gene

  • hsa-mir-653_MI0003674_Homo_sapiens_miR-653_stem-loop_hairpin

mRNA/cDNA for MIR653 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR653 Gene

No ASD Table

Relevant External Links for MIR653 Gene

GeneLoc Exon Structure for
MIR653
ECgene alternative splicing isoforms for
MIR653

Expression for MIR653 Gene

mRNA expression in normal human tissues for MIR653 Gene

genes like me logo Genes that share expressions with MIR653: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR653 Gene

Orthologs for MIR653 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR653 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-653 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-653 36
  • 87 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-653 36
  • 92 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir653 36
  • 85 (a)
OneToOne
Species with no ortholog for MIR653:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR653 Gene

ENSEMBL:
Gene Tree for MIR653 (if available)
TreeFam:
Gene Tree for MIR653 (if available)

Paralogs for MIR653 Gene

No data available for Paralogs for MIR653 Gene

Variants for MIR653 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR653 Gene

Variant ID Type Subtype PubMed ID
nsv888737 CNV Loss 21882294

Relevant External Links for MIR653 Gene

HapMap Linkage Disequilibrium report
MIR653

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for MIR653 Gene

Disorders for MIR653 Gene

No disorders were found for MIR653 Gene.

No data available for UniProtKB/Swiss-Prot for MIR653 Gene

Publications for MIR653 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. The colorectal microRNAome. (PMID: 16505370) Cummins J.M. … Velculescu V.E. (Proc. Natl. Acad. Sci. U.S.A. 2006) 3
  3. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  4. Birth and expression evolution of mammalian microRNA genes. (PMID: 23034410) Meunier J. … Kaessmann H. (Genome Res. 2013) 3

Products for MIR653 Gene

Sources for MIR653 Gene

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