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Aliases for MIR6506 Gene

Subcategory (RNA class) for MIR6506 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR6506 Gene

  • MicroRNA 6506 2 3 5
  • MicroRNA Mir-6506 3
  • Hsa-Mir-6506 3

External Ids for MIR6506 Gene

Previous GeneCards Identifiers for MIR6506 Gene

  • GC16U901692

Summaries for MIR6506 Gene

Entrez Gene Summary for MIR6506 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6506 Gene

MIR6506 (MicroRNA 6506) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR6506 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR6506 Gene

Genomics for MIR6506 Gene

Regulatory Elements for MIR6506 Gene

Enhancers for MIR6506 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH16H015610 0.9 ENCODE 0.7 +0.5 450 1 ELF3 FOXA2 ARID4B RAD21 ZSCAN9 RARA CREM MIXL1 THAP11 SP5 MIR6506 ENSG00000257769
GH16H015638 1.7 FANTOM5 ENCODE dbSUPER 0.3 -31.9 -31893 9 HDGF PKNOX1 FOXA2 MLX ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 ENSG00000263335 ENSG00000183458 PKD1P1 LOC100505915 PKD1P6 ENSG00000227827 NPIPP1 ENSG00000277920 C16orf45 ENSG00000263065
GH16H015628 1.2 ENCODE dbSUPER 0.4 -18.3 -18287 1 FOXA2 MLX ARID4B DMAP1 SLC30A9 FOS SP5 MXD4 MIER2 PPARG ENSG00000263335 MARF1 MIR6506
GH16H015635 1.5 FANTOM5 Ensembl ENCODE dbSUPER 0.3 -25.6 -25581 3 ZNF687 TBL1XR1 CBFB ELF1 EBF1 FOXK2 IKZF1 NBN ZBTB33 ATF7 NDE1 ENSG00000263335 C16orf45 MARF1 ENSG00000183458 MIR6506
GH16H015609 0.4 ENCODE 0.7 +1.4 1406 0 ZNF24 MIR6506 ENSG00000257769
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR6506 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR6506 Gene

Chromosome:
16
Start:
15,611,030 bp from pter
End:
15,611,095 bp from pter
Size:
66 bases
Orientation:
Minus strand

Genomic View for MIR6506 Gene

Genes around MIR6506 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR6506 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6506 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6506 Gene

Proteins for MIR6506 Gene

Post-translational modifications for MIR6506 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6506 Gene

Domains & Families for MIR6506 Gene

Gene Families for MIR6506 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR6506: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR6506 Gene

Function for MIR6506 Gene

Animal Model Products

miRNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6506 Gene

Localization for MIR6506 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6506 Gene

Pathways & Interactions for MIR6506 Gene

SuperPathways for MIR6506 Gene

No Data Available

Interacting Proteins for MIR6506 Gene

Gene Ontology (GO) - Biological Process for MIR6506 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR6506 Gene

Drugs & Compounds for MIR6506 Gene

No Compound Related Data Available

Transcripts for MIR6506 Gene

mRNA/cDNA for MIR6506 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6506 Gene

No ASD Table

Relevant External Links for MIR6506 Gene

GeneLoc Exon Structure for
MIR6506
ECgene alternative splicing isoforms for
MIR6506

Expression for MIR6506 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR6506 Gene:

MIR6506
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6506 Gene

Orthologs for MIR6506 Gene

Evolution for MIR6506 Gene

ENSEMBL:
Gene Tree for MIR6506 (if available)
TreeFam:
Gene Tree for MIR6506 (if available)

No data available for Orthologs for MIR6506 Gene

Paralogs for MIR6506 Gene

No data available for Paralogs for MIR6506 Gene

Variants for MIR6506 Gene

Sequence variations from dbSNP and Humsavar for MIR6506 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs1000797549 -- 15,611,967(+) CAGTC(G/T)TTGAG intron-variant, upstream-variant-2KB
rs1001124285 -- 15,610,553(+) AAATT(A/T)GAAAG intron-variant, downstream-variant-500B
rs1002123195 -- 15,612,084(+) TTTAG(C/T)GAGTG intron-variant, upstream-variant-2KB
rs1002539641 -- 15,611,301(+) AAAAA(C/T)AGAAA intron-variant, upstream-variant-2KB
rs1004062584 -- 15,611,731(+) TCCAA(C/G)AATCT nc-transcript-variant, upstream-variant-2KB, reference, missense

Structural Variations from Database of Genomic Variants (DGV) for MIR6506 Gene

Variant ID Type Subtype PubMed ID
dgv4924n54 CNV gain 21841781
esv2714015 CNV deletion 23290073
esv3638034 CNV gain 21293372
esv3638038 CNV gain 21293372
nsv1047898 CNV loss 25217958
nsv1049647 CNV gain+loss 25217958
nsv1125134 CNV deletion 24896259
nsv435664 CNV deletion 17901297
nsv457428 CNV gain 19166990
nsv469626 CNV loss 16826518
nsv819327 CNV loss 19587683

Relevant External Links for MIR6506 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6506

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR6506 Gene

Disorders for MIR6506 Gene

Relevant External Links for MIR6506

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR6506

No disorders were found for MIR6506 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6506 Gene

Publications for MIR6506 Gene

  1. Deep sequencing of small RNAs from human skin reveals major alterations in the psoriasis miRNAome. (PMID: 21807764) Joyce CE … Bowcock AM (Human molecular genetics 2011) 3 60
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR6506 Gene

Sources for MIR6506 Gene

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