Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR6500 Gene

Subcategory (RNA class) for MIR6500 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR6500 Gene

  • MicroRNA 6500 2 3 5
  • MicroRNA Mir-6500 3
  • Hsa-Mir-6500 3

External Ids for MIR6500 Gene

Previous GeneCards Identifiers for MIR6500 Gene

  • GC01U904015

Summaries for MIR6500 Gene

Entrez Gene Summary for MIR6500 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6500 Gene

MIR6500 (MicroRNA 6500) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR6500 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR6500 Gene

Genomics for MIR6500 Gene

Regulatory Elements for MIR6500 Gene

Enhancers for MIR6500 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01H051062 0.6 ENCODE 0.7 +3.1 3088 1.6 JUND JUN CEBPB FOS EP300 ATF2 MIR6500 C1orf185
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR6500 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR6500 Gene

Genomic Locations for MIR6500 Gene
chr1:51,060,018-51,060,103
(GRCh38/hg38)
Size:
86 bases
Orientation:
Plus strand

Genomic View for MIR6500 Gene

Genes around MIR6500 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR6500 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6500 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6500 Gene

Proteins for MIR6500 Gene

Post-translational modifications for MIR6500 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6500 Gene

Domains & Families for MIR6500 Gene

Gene Families for MIR6500 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR6500: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR6500 Gene

Function for MIR6500 Gene

Phenotypes From GWAS Catalog for MIR6500 Gene

Animal Model Products

miRNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6500 Gene

Localization for MIR6500 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6500 Gene

Pathways & Interactions for MIR6500 Gene

SuperPathways for MIR6500 Gene

No Data Available

Interacting Proteins for MIR6500 Gene

Gene Ontology (GO) - Biological Process for MIR6500 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR6500 Gene

Drugs & Compounds for MIR6500 Gene

No Compound Related Data Available

Transcripts for MIR6500 Gene

mRNA/cDNA for MIR6500 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6500 Gene

No ASD Table

Relevant External Links for MIR6500 Gene

GeneLoc Exon Structure for
MIR6500
ECgene alternative splicing isoforms for
MIR6500

Expression for MIR6500 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR6500 Gene:

MIR6500
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6500 Gene

Orthologs for MIR6500 Gene

Evolution for MIR6500 Gene

ENSEMBL:
Gene Tree for MIR6500 (if available)
TreeFam:
Gene Tree for MIR6500 (if available)

No data available for Orthologs for MIR6500 Gene

Paralogs for MIR6500 Gene

No data available for Paralogs for MIR6500 Gene

Variants for MIR6500 Gene

Sequence variations from dbSNP and Humsavar for MIR6500 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000792973 -- 51,058,669(+) ATGGC(C/T)GTAGA upstream-variant-2KB
rs1002770765 -- 51,059,452(+) CTGTA(A/G)GCAAA upstream-variant-2KB
rs1002834085 -- 51,058,248(+) AATTT(C/T)TTTCT upstream-variant-2KB
rs1003418212 -- 51,059,099(+) CCTAA(C/G)AAGTC upstream-variant-2KB
rs1005899350 -- 51,059,858(+) CTGAG(A/G)GTTGA nc-transcript-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR6500 Gene

Variant ID Type Subtype PubMed ID
nsv947428 CNV duplication 23825009

Relevant External Links for MIR6500 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6500

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR6500 Gene

Disorders for MIR6500 Gene

Relevant External Links for MIR6500

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR6500

No disorders were found for MIR6500 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6500 Gene

Publications for MIR6500 Gene

  1. Deep sequencing of small RNAs from human skin reveals major alterations in the psoriasis miRNAome. (PMID: 21807764) Joyce CE … Bowcock AM (Human molecular genetics 2011) 3 60
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60
  3. Downregulation of miR-137 and miR-6500-3p promotes cell proliferation in pediatric high-grade gliomas. (PMID: 26933822) Liang ML … Wang HW (Oncotarget 2016) 3

Products for MIR6500 Gene

Sources for MIR6500 Gene

Content
Loading form....