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MIR647 Gene(RNA Gene)

MicroRNA 647

GCID:
GC20M063942
GIFtS:
15
Genes Participants
UDN Logo

Aliases for MIR647 Gene

Subcategory (RNA class) for MIR647 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR647 Gene

  • MicroRNA 647 2 3 5
  • Hsa-Mir-647 3
  • MIRN647 3

External Ids for MIR647 Gene

ORGUL Members for MIR647 Gene

Previous HGNC Symbols for MIR647 Gene

  • MIRN647

Previous GeneCards Identifiers for MIR647 Gene

  • GC20M062045
  • GC20M062573

Summaries for MIR647 Gene

Entrez Gene Summary for MIR647 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR647 Gene

MIR647 (MicroRNA 647) is an RNA Gene, and is affiliated with the miRNA class.

fRNAdb sequence ontologies for MIR647 Gene - the ORGUL cluster for this gene includes several descriptions:

  • miRNA: Small, ~22-nt, RNA molecule that is the endogenous transcript of a miRNA gene. Micro RNAs are produced from precursor molecules (SO:0000647) that can form local hairpin structures, which ordinarily are processed (via the Dicer pathway) such that a single miRNA molecule accumulates from one arm of a hairpin precursor molecule. Micro RNAs may trigger the cleavage of their target molecules or act as translational repressors.

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR647 Gene

Genomics for MIR647 Gene

Products:

  1. Regulatory Element

Regulatory Elements for MIR647 Gene

Enhancers for MIR647 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MIR647 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR647 Gene

Chromosome:
20
Start:
63,942,631 bp from pter
End:
63,942,726 bp from pter
Size:
96 bases
Orientation:
Minus strand

Genomic View for MIR647 Gene

Genes around MIR647 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR647 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR647 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for MIR647 Gene

ORGUL Member Location for MIR647 Gene

ORGUL Member Location for MIR647 gene

Proteins for MIR647 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for MIR647 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR647 Gene

Domains & Families for MIR647 Gene

Gene Families for MIR647 Gene

HGNC:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR647: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR647 Gene

Function for MIR647 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line
  7. Flow Cytometry

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR647 Gene

Localization for MIR647 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR647 Gene

Pathways & Interactions for MIR647 Gene

SuperPathways for MIR647 Gene

PathCards logoMore details on SuperPathways for MIR647
No Data Available

Interacting Proteins for MIR647 Gene

Gene Ontology (GO) - Biological Process for MIR647 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR647 Gene

Drugs & Compounds for MIR647 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for MIR647 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone
  5. Flow Cytometry

mRNA/cDNA for MIR647 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR647 Gene

No ASD Table

Relevant External Links for MIR647 Gene

GeneLoc Exon Structure for
MIR647
ECgene alternative splicing isoforms for
MIR647

Expression for MIR647 Gene

Products:

  1. Primer

mRNA expression in normal human tissues for MIR647 Gene

mRNA expression in normal human tissues for MIR647 Gene
mRNA expression by GTEx for MIR647 Gene
genes like me logo Genes that share expression patterns with MIR647: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR647 Gene

Orthologs for MIR647 Gene

Evolution for MIR647 Gene

ENSEMBL:
Gene Tree for MIR647 (if available)
TreeFam:
Gene Tree for MIR647 (if available)

No data available for Orthologs for MIR647 Gene

Paralogs for MIR647 Gene

No data available for Paralogs for MIR647 Gene

Variants for MIR647 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR647 Gene

Variant ID Type Subtype PubMed ID
nsv913190 CNV Loss 21882294
nsv428381 CNV Gain+Loss 18775914
nsv913250 CNV Loss 21882294
nsv509784 CNV Insertion 20534489
nsv913269 CNV Loss 21882294
nsv469773 CNV Gain 16826518
nsv913270 CNV Loss 21882294
dgv4652n71 CNV Loss 21882294
dgv4653n71 CNV Loss 21882294
dgv4654n71 CNV Loss 21882294
dgv4655n71 CNV Loss 21882294
dgv4656n71 CNV Loss 21882294
nsv913285 CNV Gain 21882294

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Variation tolerance and Relevant External Links for MIR647 Gene

Disorders for MIR647 Gene

Relevant External Links for MIR647

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR647

No disorders were found for MIR647 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR647 Gene

Publications for MIR647 Gene

  1. Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. (PMID: 23535732) Eeles R.A. … Easton D.F. (Nat. Genet. 2013) 3 67
  2. The colorectal microRNAome. (PMID: 16505370) Cummins J.M. … Velculescu V.E. (Proc. Natl. Acad. Sci. U.S.A. 2006) 1 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3

Products for MIR647 Gene

Sources for MIR647 Gene

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