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Aliases for MIR645 Gene

Subcategory (RNA class) for MIR645 Gene


Quality Score for this RNA gene is


Aliases for MIR645 Gene

  • MicroRNA 645 2 3
  • Hsa-Mir-645 3
  • MIRN645 3

External Ids for MIR645 Gene

ORGUL Members for MIR645 Gene

Previous HGNC Symbols for MIR645 Gene

  • MIRN645

Previous GeneCards Identifiers for MIR645 Gene

  • GC20P048636
  • GC20P049202

Summaries for MIR645 Gene

Entrez Gene Summary for MIR645 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR645 Gene

MIR645 (MicroRNA 645) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR645 Gene

Genomics for MIR645 Gene

Genomic Location for MIR645 Gene

50,585,786 bp from pter
50,585,879 bp from pter
94 bases
Plus strand

Genomic View for MIR645 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR645 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR645 Gene

No data available for Regulatory Elements for MIR645 Gene

Proteins for MIR645 Gene

Post-translational modifications for MIR645 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR645 Gene

Domains & Families for MIR645 Gene

Gene Families for MIR645 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR645: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR645 Gene

Function for MIR645 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR645 Gene

Localization for MIR645 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR645 Gene

Pathways & Interactions for MIR645 Gene

SuperPathways for MIR645 Gene

No Data Available

Interacting Proteins for MIR645 Gene

Gene Ontology (GO) - Biological Process for MIR645 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR645 Gene

Drugs & Compounds for MIR645 Gene

No Compound Related Data Available

Transcripts for MIR645 Gene

mRNA/cDNA for MIR645 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR645 Gene

No ASD Table

Relevant External Links for MIR645 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR645 Gene

mRNA expression in normal human tissues for MIR645 Gene

genes like me logo Genes that share expression patterns with MIR645: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR645 Gene

Orthologs for MIR645 Gene

Evolution for MIR645 Gene

Gene Tree for MIR645 (if available)
Gene Tree for MIR645 (if available)

No data available for Orthologs for MIR645 Gene

Paralogs for MIR645 Gene

No data available for Paralogs for MIR645 Gene

Variants for MIR645 Gene

Sequence variations from dbSNP and Humsavar for MIR645 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type MAF
rs112736998 -- 50,585,537(+) GAACC(A/G)GTTCC upstream-variant-2KB
rs533688475 -- 50,585,511(+) CGGTC(C/G)CCAAC upstream-variant-2KB
rs542551541 -- 50,585,359(+) AGGCC(C/T)AGGCT upstream-variant-2KB
rs560282938 -- 50,585,536(+) GGAAC(C/T)GGTTC upstream-variant-2KB
rs575172181 -- 50,585,301(+) AGTAC(A/G)AAGAG upstream-variant-2KB

Relevant External Links for MIR645 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR645 Gene

Disorders for MIR645 Gene

Relevant External Links for MIR645

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with MIR645: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR645 Gene

Publications for MIR645 Gene

  1. MicroRNA-645, up-regulated in human adencarcinoma of gastric esophageal junction, inhibits apoptosis by targeting tumor suppressor IFIT2. (PMID: 25174799) Feng X. … Gao S. (BMC Cancer 2014) 67
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 67
  3. The colorectal microRNAome. (PMID: 16505370) Cummins J.M. … Velculescu V.E. (Proc. Natl. Acad. Sci. U.S.A. 2006) 67

Products for MIR645 Gene

Sources for MIR645 Gene

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