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Aliases for MIR643 Gene

Subcategory (RNA class) for MIR643 Gene


Quality Score for this RNA gene is


Aliases for MIR643 Gene

  • MicroRNA 643 2 3 5
  • Hsa-Mir-643 3
  • Mir-643 3
  • MIRN643 3

External Ids for MIR643 Gene

ORGUL Members for MIR643 Gene

Previous HGNC Symbols for MIR643 Gene

  • MIRN643

Previous GeneCards Identifiers for MIR643 Gene

  • GC19P057478
  • GC19P052785

Summaries for MIR643 Gene

Entrez Gene Summary for MIR643 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR643 Gene

MIR643 (MicroRNA 643) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR643 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR643 Gene

Genomics for MIR643 Gene

Genomic Locations for MIR643 Gene

Genomic Locations for MIR643 Gene
97 bases
Plus strand

Genomic View for MIR643 Gene

Genes around MIR643 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR643 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR643 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR643 Gene

No data available for GeneHancer (GH) Regulatory Elements for MIR643 Gene

Proteins for MIR643 Gene

Post-translational modifications for MIR643 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR643 Gene

Domains & Families for MIR643 Gene

Gene Families for MIR643 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR643: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR643 Gene

Function for MIR643 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR643 Gene

Localization for MIR643 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR643 Gene

Pathways & Interactions for MIR643 Gene

SuperPathways for MIR643 Gene

No Data Available

Interacting Proteins for MIR643 Gene

Gene Ontology (GO) - Biological Process for MIR643 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR643 Gene

Drugs & Compounds for MIR643 Gene

No Compound Related Data Available

Transcripts for MIR643 Gene

mRNA/cDNA for MIR643 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR643 Gene

No ASD Table

Relevant External Links for MIR643 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR643 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR643 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR643 Gene:

genes like me logo Genes that share expression patterns with MIR643: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR643 Gene

Orthologs for MIR643 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR643 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ptr-mir-643 34
  • 98 (a)
Species where no ortholog for MIR643 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR643 Gene

Gene Tree for MIR643 (if available)
Gene Tree for MIR643 (if available)

Paralogs for MIR643 Gene

No data available for Paralogs for MIR643 Gene

Variants for MIR643 Gene

Sequence variations from dbSNP and Humsavar for MIR643 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1004003939 -- 52,280,453(+) G/A/C/T upstream_transcript_variant
rs1004420829 -- 52,280,249(+) T/G upstream_transcript_variant
rs1004665830 -- 52,280,293(+) A/G upstream_transcript_variant
rs1005683069 -- 52,281,350(+) C/T upstream_transcript_variant
rs1006310657 -- 52,281,421(+) A/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR643 Gene

Variant ID Type Subtype PubMed ID
nsv1140251 OTHER inversion 24896259
nsv960862 CNV duplication 23825009

Additional Variant Information for MIR643 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR643 Gene

Disorders for MIR643 Gene

Additional Disease Information for MIR643

No disorders were found for MIR643 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR643 Gene

Publications for MIR643 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58
  3. The colorectal microRNAome. (PMID: 16505370) Cummins JM … Velculescu VE (Proceedings of the National Academy of Sciences of the United States of America 2006) 3 58

Products for MIR643 Gene

Sources for MIR643 Gene

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