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MIR642B Gene(RNA Gene)

MicroRNA 642b

GCID:
GC19M045674
GIFtS:
10
Genes Participants
UDN Logo

Aliases for MIR642B Gene

Subcategory (RNA class) for MIR642B Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR642B Gene

  • MicroRNA 642b 2 3 5
  • Hsa-Mir-642b 3
  • Mir-642b 3

External Ids for MIR642B Gene

ORGUL Members for MIR642B Gene

Previous GeneCards Identifiers for MIR642B Gene

  • GC19U901469
  • GC19M046181

Summaries for MIR642B Gene

Entrez Gene Summary for MIR642B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR642B Gene

MIR642B (MicroRNA 642b) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR642B Gene

Genomics for MIR642B Gene

Products:

  1. Regulatory Element

Regulatory Elements for MIR642B Gene

Enhancers for MIR642B Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19G045677 0.9 ENCODE 0.7 -2.5 -2518 1.4 ELF3 HDGF ATF1 PKNOX1 AGO1 RAD21 ZBTB7B ZNF335 EGR1 ZNF143 GIPR PNMA8A GC19M045670 MIR642B
GH19G045676 0.6 ENCODE 0.7 -1.8 -1765 0.1 ZBTB49 MXI1 POLR2A BACH1 PRDM10 RBFOX2 EZH2 SUPT5H GC19M045670 MIR642B
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR642B on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR642B Gene

Chromosome:
19
Start:
45,674,932 bp from pter
End:
45,675,008 bp from pter
Size:
77 bases
Orientation:
Minus strand

Genomic View for MIR642B Gene

Genes around MIR642B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR642B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR642B Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for MIR642B Gene

ORGUL Member Location for MIR642B Gene

ORGUL Member Location for MIR642B gene

Proteins for MIR642B Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for MIR642B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR642B Gene

Domains & Families for MIR642B Gene

Gene Families for MIR642B Gene

HGNC:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR642B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR642B Gene

Function for MIR642B Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line
  7. Flow Cytometry

Animal Model Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR642B Gene

Localization for MIR642B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR642B Gene

Pathways & Interactions for MIR642B Gene

SuperPathways for MIR642B Gene

PathCards logo More details on SuperPathways for MIR642B
No Data Available

Interacting Proteins for MIR642B Gene

Gene Ontology (GO) - Biological Process for MIR642B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR642B Gene

Drugs & Compounds for MIR642B Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for MIR642B Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone
  5. Flow Cytometry

mRNA/cDNA for MIR642B Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR642B Gene

No ASD Table

Relevant External Links for MIR642B Gene

GeneLoc Exon Structure for
MIR642B
ECgene alternative splicing isoforms for
MIR642B

Expression for MIR642B Gene

Products:

  1. Primer

NURSA nuclear receptor signaling pathways regulating expression of MIR642B Gene:

MIR642B
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR642B Gene

Orthologs for MIR642B Gene

Evolution for MIR642B Gene

ENSEMBL:
Gene Tree for MIR642B (if available)
TreeFam:
Gene Tree for MIR642B (if available)

No data available for Orthologs for MIR642B Gene

Paralogs for MIR642B Gene

No data available for Paralogs for MIR642B Gene

Variants for MIR642B Gene

Sequence variations from dbSNP and Humsavar for MIR642B Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1000773495 -- 45,674,830(+) AGGTG(A/G)GCATC intron-variant, downstream-variant-500B, upstream-variant-2KB
rs1002804291 -- 45,676,502(+) AATCT(A/C/G)GGCTC intron-variant, upstream-variant-2KB
rs1003079576 -- 45,676,152(+) GAGCC(A/G)AGATC intron-variant, upstream-variant-2KB
rs1004805419 -- 45,675,827(+) AGGCT(A/G)CAGTG intron-variant, upstream-variant-2KB
rs1004926418 -- 45,675,450(+) GACAC(C/T)TGTAA intron-variant, downstream-variant-500B, upstream-variant-2KB

Relevant External Links for MIR642B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR642B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR642B Gene

Disorders for MIR642B Gene

Relevant External Links for MIR642B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR642B

No disorders were found for MIR642B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR642B Gene

Publications for MIR642B Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Ultra-high throughput sequencing-based small RNA discovery and discrete statistical biomarker analysis in a collection of cervical tumours and matched controls. (PMID: 20459774) Witten D. … Lui W.O. (BMC Biol. 2010) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR642B Gene

Sources for MIR642B Gene

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