Aliases for MIR642B Gene
Subcategory (RNA class) for MIR642B Gene
miRNA
Quality Score for this RNA gene is
8
External Ids for MIR642B Gene
- HGNC: 38902
- Entrez Gene: 100500845
- Ensembl: ENSG00000283212
- miRBase: hsa-mir-642b
ORGUL Members for MIR642B Gene
Previous GeneCards Identifiers for MIR642B Gene
- GC19U901469
- GC19M046181
Summaries for MIR642B Gene
-
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
GeneCards Summary for MIR642B Gene
MIR642B (MicroRNA 642b) is an RNA Gene, and is affiliated with the miRNA class.
Additional gene information for MIR642B Gene
No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR642B Gene
Genomics for MIR642B Gene
GeneHancer (GH) Regulatory Elements for MIR642B Gene
Promoters and enhancers for MIR642B Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH19I045676 | Enhancer | 0.5 | ENCODE | 550.8 | -1.8 | -1765 | 0.1 | ZBTB49 POLR2B BACH1 PRDM10 SUPT5H EZH2 | GC19P045675 GC19P045676 MIR642A MIR642B CLASRP CCDC61 SYMPK FBXO46 ENSG00000268810 ENSG00000269148 | |
| GH19I045677 | Promoter/Enhancer | 1.3 | Ensembl ENCODE | 0.8 | -2.5 | -2517 | 1.4 | HDGF ELF3 CTCF PKNOX1 ZNF449 BACH1 SIN3A ZBTB7B TEAD3 ZFHX2 | SNRPD2 CCDC61 GIPR PNMA8A GC19M045670 MIR642B GC19P045665 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around MIR642B on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for MIR642B Gene
Genomic Locations for MIR642B Gene
- chr19:45,674,932-45,675,008
- (GRCh38/hg38)
- Size:
- 77 bases
- Orientation:
- Minus strand
- chr19:46,178,190-46,178,266
- (GRCh37/hg19)
Genomic View for MIR642B Gene
Genes around MIR642B on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19q13.32 by Ensembl
- 19q13.32 by Entrez Gene
- 19q13.32 by HGNC
MIR642B Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MIR642B Gene
ORGUL Member Location for MIR642B Gene
Proteins for MIR642B Gene
Post-translational modifications for MIR642B Gene
No Post-translational modifications
Antibody Products
- Search GeneTex for Antibodies for MIR642B
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR642B
- Origene Custom Protein Services for MIR642B
- Search GeneTex for Proteins for MIR642B
No data available for DME Specific Peptides for MIR642B Gene
Domains & Families for MIR642B Gene
Gene Families for MIR642B Gene
- HGNC:
Graphical View of Domain Structure for InterPro Entry
No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR642B Gene
Function for MIR642B Gene
Phenotypes From GWAS Catalog for MIR642B Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR642B
-
- Search ViGene Biosciences for MIR642B
CRISPR Products
- Browse CRISPR knockouts for MIR642B
- Applied Biological Materials CRISPR for MIR642B
-
Vectors and viruses for KO, Activation, Repression, and more
miRNA Products
- Search ViGene Biosciences for MIR642B
Inhibitory RNA Products
- Search ViGene Biosciences for MIR642B
Clone Products
- GenScript: Custom all cDNA clones Services for MIR642B
- VectorBuilder custom plasmid, inducible vectors for MIR642B
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR642B
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for MIR642B
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR642B Gene
Localization for MIR642B Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR642B Gene
Transcripts for MIR642B Gene
mRNA/cDNA for MIR642B Gene
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
- Browse CRISPR knockouts for MIR642B
- Applied Biological Materials CRISPR for MIR642B
-
Vectors and viruses for KO, Activation, Repression, and more
miRNA Products
- Search ViGene Biosciences for MIR642B
Inhibitory RNA Products
- Search ViGene Biosciences for MIR642B
Clone Products
- GenScript: Custom all cDNA clones Services for MIR642B
- VectorBuilder custom plasmid, inducible vectors for MIR642B
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR642B
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for MIR642B
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for MIR642B Gene
NURSA nuclear receptor signaling pathways regulating expression of MIR642B Gene:
MIR642B
No Expression Related Data Available
Primer Products
No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR642B Gene
Orthologs for MIR642B Gene
No data available for Orthologs for MIR642B Gene
Paralogs for MIR642B Gene
No data available for Paralogs for MIR642B Gene
Variants for MIR642B Gene
| SNP ID | Clin | Chr 19 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000773495 | -- | 45,674,830(-) | G/A | downstream_transcript_variant | |
| rs1002804291 | -- | 45,676,502(-) | C/A/G | upstream_transcript_variant | |
| rs1003079576 | -- | 45,676,152(-) | G/A | upstream_transcript_variant | |
| rs1004805419 | -- | 45,675,827(-) | G/A | upstream_transcript_variant | |
| rs1004926418 | -- | 45,675,450(-) | C/T | upstream_transcript_variant |
Additional Variant Information for MIR642B Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- MIR642B
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR642B Gene
Disorders for MIR642B Gene
Additional Disease Information for MIR642B
No disorders were found for MIR642B Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR642B Gene
Publications for MIR642B Gene
- MicroRNA expression profiling in Guillain-Barré syndrome. (PMID: 27836180) Lv Z … Wang Y (Journal of neuroimmunology 2016) 3 58
- miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
- Ultra-high throughput sequencing-based small RNA discovery and discrete statistical biomarker analysis in a collection of cervical tumours and matched controls. (PMID: 20459774) Witten D … Lui WO (BMC biology 2010) 3 58
- miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58
Products for MIR642B Gene
- Browse R&D Systems for Antibodies
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- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
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- Custom Assay Services
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- Novus Biologicals
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- Browse Antibodies at Cloud-Clone Corp.
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- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR642B
- VectorBuilder custom plasmid, inducible vectors for MIR642B
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR642B
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneTex for Antibodies for MIR642B
- Search GeneTex for Proteins for MIR642B
Sources for MIR642B Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew