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Aliases for MIR642A Gene

Subcategory (RNA class) for MIR642A Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR642A Gene

  • MicroRNA 642a 2 3 5
  • MicroRNA 642 2 3
  • MicroRNA Mir-642a 3
  • Hsa-Mir-642a 3
  • Hsa-Mir-642 3
  • Mir-642a 3
  • MIRN642 3
  • MIR642 3

External Ids for MIR642A Gene

ORGUL Members for MIR642A Gene

Previous HGNC Symbols for MIR642A Gene

  • MIRN642
  • MIR642

Previous GeneCards Identifiers for MIR642A Gene

  • GC19P046179

Summaries for MIR642A Gene

Entrez Gene Summary for MIR642A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR642A Gene

MIR642A (MicroRNA 642a) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR642A Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR642A Gene

Genomics for MIR642A Gene

Regulatory Elements for MIR642A Gene

Enhancers for MIR642A Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19H045567 1.4 Ensembl ENCODE dbSUPER 11.4 -105.7 -105738 2 PKNOX1 RB1 INSM2 KLF17 SIN3A FEZF1 ZBTB40 RAD21 ZEB1 YY1 CCDC61 SYMPK OPA3 CLASRP BLOC1S3 VASP ENSG00000269148 FBXO46 RTN2 PPM1N
GH19H045706 0.8 ENCODE 11.9 +32.1 32075 1 PKNOX1 TBL1XR1 RB1 ZNF143 ZNF207 ATF7 RUNX3 IKZF2 CREM SMARCA5 FBXO46 MIR642A FOXA3 SYMPK DMWD PNMA8A PIR45336 SNRPD2
GH19H045571 0.2 dbSUPER 11.4 -103.3 -103281 0 VASP EML2 RN7SL836P GIPR RTN2 PPM1N MIR330 MIR642A ERCC1 PPP1R13L
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR642A on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR642A Gene

Chromosome:
19
Start:
45,674,928 bp from pter
End:
45,675,024 bp from pter
Size:
97 bases
Orientation:
Plus strand

Genomic View for MIR642A Gene

Genes around MIR642A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR642A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR642A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR642A Gene

Proteins for MIR642A Gene

Post-translational modifications for MIR642A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR642A Gene

Domains & Families for MIR642A Gene

Gene Families for MIR642A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR642A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR642A Gene

Function for MIR642A Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR642A
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR642A Gene

Localization for MIR642A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR642A Gene

Pathways & Interactions for MIR642A Gene

SuperPathways for MIR642A Gene

No Data Available

Interacting Proteins for MIR642A Gene

Gene Ontology (GO) - Biological Process for MIR642A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR642A Gene

Drugs & Compounds for MIR642A Gene

No Compound Related Data Available

Transcripts for MIR642A Gene

mRNA/cDNA for MIR642A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR642A
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR642A Gene

No ASD Table

Relevant External Links for MIR642A Gene

GeneLoc Exon Structure for
MIR642A
ECgene alternative splicing isoforms for
MIR642A

Expression for MIR642A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR642A Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR642A Gene:

MIR642A
genes like me logo Genes that share expression patterns with MIR642A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR642A Gene

Orthologs for MIR642A Gene

Evolution for MIR642A Gene

ENSEMBL:
Gene Tree for MIR642A (if available)
TreeFam:
Gene Tree for MIR642A (if available)

No data available for Orthologs for MIR642A Gene

Paralogs for MIR642A Gene

No data available for Paralogs for MIR642A Gene

Variants for MIR642A Gene

Sequence variations from dbSNP and Humsavar for MIR642A Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1000773495 -- 45,674,830(+) AGGTG(A/G)GCATC intron-variant, downstream-variant-500B, upstream-variant-2KB
rs1001102881 -- 45,673,739(+) CGCAC(C/G)TGTAG intron-variant, upstream-variant-2KB
rs1004917287 -- 45,674,056(+) CTTCC(C/T)CTTCT intron-variant, upstream-variant-2KB
rs1004926418 -- 45,675,450(+) GACAC(C/T)TGTAA intron-variant, downstream-variant-500B, upstream-variant-2KB
rs1005147066 -- 45,674,562(+) TGATT(A/G)TGTCA intron-variant, downstream-variant-500B, upstream-variant-2KB

Relevant External Links for MIR642A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR642A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR642A Gene

Disorders for MIR642A Gene

Relevant External Links for MIR642A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR642A

No disorders were found for MIR642A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR642A Gene

Publications for MIR642A Gene

  1. A novel biomarker Linc00974 interacting with KRT19 promotes proliferation and metastasis in hepatocellular carcinoma. (PMID: 25476897) Tang J … Sun B (Cell death & disease 2014) 3 60
  2. A microRNA signature defines chemoresistance in ovarian cancer through modulation of angiogenesis. (PMID: 23697367) Vecchione A … Croce CM (Proceedings of the National Academy of Sciences of the United States of America 2013) 3 60
  3. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 60
  4. Small RNA sequencing reveals miR-642a-3p as a novel adipocyte-specific microRNA and miR-30 as a key regulator of human adipogenesis. (PMID: 21767385) Zaragosi LE … Barbry P (Genome biology 2011) 3 60
  5. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P … Tuschl T (Cell 2007) 3 60

Products for MIR642A Gene

Sources for MIR642A Gene

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