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Aliases for MIR641 Gene

Subcategory (RNA class) for MIR641 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR641 Gene

  • MicroRNA 641 2 3
  • Hsa-Mir-641 3
  • MIRN641 3

External Ids for MIR641 Gene

Previous HGNC Symbols for MIR641 Gene

  • MIRN641

Previous GeneCards Identifiers for MIR641 Gene

  • GC19M045481
  • GC19M040788

Summaries for MIR641 Gene

Entrez Gene Summary for MIR641 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR641 Gene

MIR641 (MicroRNA 641) is an RNA Gene, and is affiliated with the miRNA class.

fRNAdb sequence ontologies for MIR641 Gene - the ORGUL cluster for this gene includes several descriptions:

  • miRNA: Small, ~22-nt, RNA molecule that is the endogenous transcript of a miRNA gene. Micro RNAs are produced from precursor molecules (SO:0000647) that can form local hairpin structures, which ordinarily are processed (via the Dicer pathway) such that a single miRNA molecule accumulates from one arm of a hairpin precursor molecule. Micro RNAs may trigger the cleavage of their target molecules or act as translational repressors.

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR641

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR641 Gene

Genomics for MIR641 Gene

Genomic Location for MIR641 Gene

Start:
40,282,543 bp from pter
End:
40,282,641 bp from pter
Size:
99 bases
Orientation:
Minus strand

Genomic View for MIR641 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR641 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR641 Gene

ORGUL Member Location for MIR641 Gene

ORGUL Member Location for MIR641 gene

No data available for Regulatory Elements for MIR641 Gene

Proteins for MIR641 Gene

Post-translational modifications for MIR641 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR641 Gene

Domains for MIR641 Gene

Gene Families for MIR641 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR641: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR641 Gene

Function for MIR641 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR641 Gene

Localization for MIR641 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR641 Gene

Pathways for MIR641 Gene

SuperPathways for MIR641 Gene

No Data Available

Interacting Proteins for MIR641 Gene

Gene Ontology (GO) - Biological Process for MIR641 Gene

None

No data available for Pathways by source for MIR641 Gene

Transcripts for MIR641 Gene

fRNAdb Secondary structures for MIR641 Gene

  • hsa-mir-641_MI0003656_Homo_sapiens_miR-641_stem-loop_hairpin

mRNA/cDNA for MIR641 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MIR641

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR641 Gene

No ASD Table

Relevant External Links for MIR641 Gene

GeneLoc Exon Structure for
MIR641
ECgene alternative splicing isoforms for
MIR641

Expression for MIR641 Gene

mRNA expression in normal human tissues for MIR641 Gene

genes like me logo Genes that share expressions with MIR641: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR641 Gene

Orthologs for MIR641 Gene

Evolution for MIR641 Gene

ENSEMBL:
Gene Tree for MIR641 (if available)
TreeFam:
Gene Tree for MIR641 (if available)

No data available for Orthologs for MIR641 Gene

Paralogs for MIR641 Gene

No data available for Paralogs for MIR641 Gene

Variants for MIR641 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR641 Gene

Variant ID Type Subtype PubMed ID
dgv1083e1 CNV Complex 17122850
nsv911699 CNV Loss 21882294
esv1005660 CNV Deletion 20482838

Relevant External Links for MIR641 Gene

HapMap Linkage Disequilibrium report
MIR641

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for MIR641 Gene

Disorders for MIR641 Gene

No disorders were found for MIR641 Gene.

No data available for UniProtKB/Swiss-Prot for MIR641 Gene

Publications for MIR641 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. The colorectal microRNAome. (PMID: 16505370) Cummins J.M. … Velculescu V.E. (Proc. Natl. Acad. Sci. U.S.A. 2006) 3

Products for MIR641 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate MIR641
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for MIR641
    • Block miRNA regulation of MIR641 using miScript Target Protectors

    Sources for MIR641 Gene

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