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Aliases for MIR640 Gene

Subcategory (RNA class) for MIR640 Gene


Quality Score for this RNA gene is


Aliases for MIR640 Gene

  • MicroRNA 640 2 3 5
  • Hsa-Mir-640 3
  • MIRN640 3

External Ids for MIR640 Gene

ORGUL Members for MIR640 Gene

Previous HGNC Symbols for MIR640 Gene

  • MIRN640

Previous GeneCards Identifiers for MIR640 Gene

  • GC19P019545

Summaries for MIR640 Gene

Entrez Gene Summary for MIR640 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR640 Gene

MIR640 (MicroRNA 640) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR640 Gene

Genomics for MIR640 Gene

Regulatory Elements for MIR640 Gene

Enhancers for MIR640 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19F019384 1.1 ENCODE 12.9 -47.7 -47719 5.3 HDGF PKNOX1 ARID4B SIN3A FEZF1 ZNF207 ZNF143 FOS KLF13 CEBPZ NDUFA13 GATAD2A MIR640 ENSG00000267234
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR640 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR640 Gene

19,435,063 bp from pter
19,435,158 bp from pter
96 bases
Plus strand

Genomic View for MIR640 Gene

Genes around MIR640 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR640 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR640 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR640 Gene

Proteins for MIR640 Gene

Post-translational modifications for MIR640 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR640 Gene

Domains & Families for MIR640 Gene

Gene Families for MIR640 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR640: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR640 Gene

Function for MIR640 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR640 Gene

Localization for MIR640 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR640 Gene

Pathways & Interactions for MIR640 Gene

SuperPathways for MIR640 Gene

No Data Available

Interacting Proteins for MIR640 Gene

Gene Ontology (GO) - Biological Process for MIR640 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR640 Gene

Transcripts for MIR640 Gene

mRNA/cDNA for MIR640 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR640 Gene

No ASD Table

Relevant External Links for MIR640 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR640 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR640 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR640 Gene:

genes like me logo Genes that share expression patterns with MIR640: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR640 Gene

Orthologs for MIR640 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR640 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ptr-mir-640 35
  • 99 (a)
Species where no ortholog for MIR640 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR640 Gene

Gene Tree for MIR640 (if available)
Gene Tree for MIR640 (if available)

Paralogs for MIR640 Gene

No data available for Paralogs for MIR640 Gene

Variants for MIR640 Gene

Sequence variations from dbSNP and Humsavar for MIR640 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs10413582 -- 19,433,914(+) caggt(A/G)cacgc intron-variant, upstream-variant-2KB
rs111726405 -- 19,435,123(+) TGGGC(A/G)TGATC intron-variant, nc-transcript-variant
rs113564583 -- 19,434,833(+) TCTGG(A/G)CAGCA intron-variant, upstream-variant-2KB
rs116539162 -- 19,433,655(+) AAACA(A/G)CAACT intron-variant, upstream-variant-2KB
rs117868357 -- 19,433,434(+) ACTTC(C/T)GTGTA intron-variant, upstream-variant-2KB

Relevant External Links for MIR640 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR640 Gene

Disorders for MIR640 Gene

Relevant External Links for MIR640

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR640 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR640 Gene

Publications for MIR640 Gene

  1. Hydrogen sulfide promotes angiogenesis by downregulating miR-640 via the VEGFR2/mTOR pathway. (PMID: 26879375) Zhou Y. … Zhu Y.C. (Am. J. Physiol., Cell Physiol. 2016) 3 64
  2. Genome-wide association analysis identifies 13 new risk loci for schizophrenia. (PMID: 23974872) Ripke S. … Sullivan P.F. (Nat. Genet. 2013) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64
  4. The colorectal microRNAome. (PMID: 16505370) Cummins J.M. … Velculescu V.E. (Proc. Natl. Acad. Sci. U.S.A. 2006) 3 64

Products for MIR640 Gene

Sources for MIR640 Gene

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